Seconal Sodium

Insomnia, Anesthetic premedication therapy
Treatment
2 FDA approvals
1 Active Study for Seconal Sodium

What is Seconal Sodium

SecobarbitalThe Generic name of this drug
Treatment SummarySecobarbital is a sedative-hypnotic drug used to treat insomnia and other sleeping disorders. It is sold under the brand names Seconal and Tuinal by Eli Lilly and Company, and known as quinalbarbitone in the United Kingdom. Secobarbital is a barbiturate, a type of drug that produces anesthetic, anticonvulsant, sedative and hypnotic effects.
Seconal Sodiumis the brand name
Seconal Sodium Overview & Background
Brand Name
Generic Name
First FDA Approval
How many FDA approvals?
Seconal Sodium
Secobarbital
1983
3

Approved as Treatment by the FDA

Secobarbital, also known as Seconal Sodium, is approved by the FDA for 2 uses such as Insomnia and Anesthetic premedication therapy .
Insomnia
Anesthetic premedication therapy

Effectiveness

How Seconal Sodium Affects PatientsSecobarbital is a type of barbiturate used to put someone to sleep before an operation or procedure. It does not provide much pain relief, and can even make pain worse if it is used while someone is in pain.
How Seconal Sodium works in the bodySecobarbital helps the brain to relax by increasing the amount of time that chloride ions can flow through the GABA receptor. This leads to a greater calming effect on the brain, especially in the thalamus.

When to interrupt dosage

The suggested dose of Seconal Sodium is contingent upon the diagnosed condition, such as Anesthetic premedication therapy, Insomnia and Preanesthetic Medication. The quantity of dosage is contingent upon the approach of delivery (e.g. Capsule - Oral or Oral) specified in the table below.
Condition
Dosage
Administration
Insomnia
, 100.0 mg, 50.0 mg
, Oral, Capsule, Capsule - Oral
Anesthetic premedication therapy
, 100.0 mg, 50.0 mg
, Oral, Capsule, Capsule - Oral

Warnings

Seconal Sodium Contraindications
Condition
Risk Level
Notes
Shortness of Breath
Do Not Combine
Porphyrias
Do Not Combine
Liver Diseases
Do Not Combine
history of respiratory disease
Do Not Combine
Severe Hypersensitivity Reactions
Do Not Combine
Secobarbital may interact with Pulse Frequency
There are 20 known major drug interactions with Seconal Sodium.
Common Seconal Sodium Drug Interactions
Drug Name
Risk Level
Description
Abemaciclib
Major
The metabolism of Abemaciclib can be increased when combined with Secobarbital.
Acalabrutinib
Major
The metabolism of Acalabrutinib can be increased when combined with Secobarbital.
Alectinib
Major
The metabolism of Alectinib can be increased when combined with Secobarbital.
Almotriptan
Major
The metabolism of Almotriptan can be increased when combined with Secobarbital.
Alpelisib
Major
The metabolism of Alpelisib can be increased when combined with Secobarbital.
Seconal Sodium Toxicity & Overdose RiskOverdosing on this drug can cause sluggishness, confusion, difficulty thinking, slow speech, impaired judgement, drowsiness, shallow breathing, and staggering. In extreme cases, it may lead to coma or death.
image of a doctor in a lab doing drug, clinical research

Seconal Sodium Novel Uses: Which Conditions Have a Clinical Trial Featuring Seconal Sodium?

82 active studies are currently assessing the use of Seconal Sodium for Anesthetic premedication therapy, Preanesthetic Medication and Insomnia relief.
Condition
Clinical Trials
Trial Phases
Anesthetic premedication therapy
0 Actively Recruiting
Insomnia
1 Actively Recruiting
Not Applicable

Seconal Sodium Reviews: What are patients saying about Seconal Sodium?

5Patient Review
12/27/2014
Seconal Sodium for Severe Anxiety
This medication always works well for me and I've never had any problems with it.
5Patient Review
2/8/2011
Seconal Sodium for Chronic Trouble Sleeping
This medication helps me sleep better and feel more relaxed during the day.
4.7Patient Review
8/20/2010
Seconal Sodium for Chronic Trouble Sleeping
I found this drug to be much more effective than the other options I had tried previously. If you've been disappointed with other medications in this category, I would highly recommend giving this one a try.
4.7Patient Review
3/6/2011
Seconal Sodium for Chronic Trouble Sleeping
This medication can be really helpful for those having trouble sleeping, as long as it's used correctly and not abused.
4Patient Review
11/9/2010
Seconal Sodium for Chronic Trouble Sleeping
This treatment is effective and I would recommend it.
image of drug pills surrounding a glass of water symbolizing drug consumption

Patient Q&A Section about seconal sodium

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Is Seconal still made?

"What is the status of Seconal (secobarbital)?

It is no longer available in the US."

Answered by AI

What is seconal sodium used for?

"This medication is used to calm you just before surgery. It is a barbiturate hypnotic and works by affecting certain parts of the brain to calm you."

Answered by AI

What is the street name for Seconal?

"While secobarbital is no longer widely used as a sleeping pill, it was at one point commonly abused, to the point where it earned nicknames like "red devils" or "reds.""

Answered by AI

How does Seconal make you feel?

"The psychoactive effects of Seconal are similar to those of alcohol. Individuals taking Seconal may feel less inhibited, more talkative and relaxed. As addiction progresses, the perceived pleasurable effects of the drug decreases, but the depressant effects on the central nervous system remain."

Answered by AI

Clinical Trials for Seconal Sodium