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LY3556050 + Metformin + Iohexol for Healthy Subjects

Phase 1
Waitlist Available
Research Sponsored by Eli Lilly and Company
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up predose on day 1 through 13 days postdose
Awards & highlights

Study Summary

The main purpose of this study is to evaluate how much Metformin gets into the bloodstream and how long the body takes to get rid of it when it is administered orally in combination with LY3556050 in healthy participants. Iohexol will be administered to evaluate kidney function. Each enrolled participant will remain in the study for up to 7 weeks including the screening period.

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~predose on day 1 through 13 days postdose
This trial's timeline: 3 weeks for screening, Varies for treatment, and predose on day 1 through 13 days postdose for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Metformin
Metformin

Trial Design

1Treatment groups
Experimental Treatment
Group I: LY3556050 + Metformin + IohexolExperimental Treatment3 Interventions
LY3556050 administered orally in combination with metformin given orally and iohexol given intravenously (IV).
Treatment
First Studied
Drug Approval Stage
How many patients have taken this drug
LY3556050
2021
Completed Phase 2
~520
Iohexol
2016
Completed Phase 4
~1920
Metformin
2006
Completed Phase 4
~2430

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Logistics

Participation is compensated

You will be compensated for participating in this trial.

Who is running the clinical trial?

Eli Lilly and CompanyLead Sponsor
2,624 Previous Clinical Trials
3,216,906 Total Patients Enrolled
Study DirectorEli Lilly and Company
1,349 Previous Clinical Trials
415,662 Total Patients Enrolled
~7 spots leftby May 2025
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