VTX2735 for Pericarditis

Park Ridge, IL

Phase 2

Recruiting

Research Sponsored by Zomagen Biosciences Ltd.

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

Previously had an index episode of pericarditis meeting the criteria for an acute pericarditis event

Participants are male or female aged 18 to 75 years

Must not have

Current or prior diagnosis of pericarditis secondary to specific prohibited causes such as tuberculosis, blunt trauma, tumor, myocarditis, or systemic autoimmune diseases

History of clinically significant immunosuppressive disorder, autoimmune/autoinflammatory disorder, or primary or secondary immunodeficiency

Timeline

Screening 3 weeks

Treatment Varies

Follow Up day 1 of treatment period through study completion, up to 15 weeks

Awards & highlights

No Placebo-Only Group

Summary

This trial aims to determine if VTX2735 is safe and effective for patients with Recurrent Pericarditis. Around 30 patients will be given VTX2735 in different stages of the

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Who is the study for?

This trial is for individuals with Recurrent Pericarditis, which means they've had multiple episodes of pericarditis. Participants must pass a screening to qualify and be willing to take the study drug VTX2735 over several weeks.Check my eligibility

What is being tested?

The trial is testing the safety and effectiveness of a medication called VTX2735 in treating Recurrent Pericarditis. Patients will receive this drug during an initial treatment period followed by an extension phase if they meet certain criteria.See study design

What are the potential side effects?

Since this summary does not provide specific side effects for VTX2735, it's important to note that potential side effects will be monitored throughout the study given its pilot nature.

Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below

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I have had a previous episode of acute pericarditis.

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I am between 18 and 75 years old.

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Exclusion Criteria

You may be eligible for the trial if you check “No” for criteria below:

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I have had pericarditis not caused by TB, injury, cancer, heart inflammation, or autoimmune diseases.

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I have a history of significant immune system disorders.

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Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ day 1 of treatment period through study completion, up to 15 weeks

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~day 1 of treatment period through study completion, up to 15 weeks

This trial's timeline: 3 weeks for screening, Varies for treatment, and day 1 of treatment period through study completion, up to 15 weeks for reporting.