Novel by Upper Airway Respiratory Muscle Training to Treat OSA in Chronic SCI (NOURMT-OSA Trial)
Recruiting in Palo Alto (17 mi)
Overseen ByAbdulghani Sankari, MD PhD
Age: 18+
Sex: Any
Travel: May be covered
Time Reimbursement: Varies
Trial Phase: Academic
Waitlist Available
Sponsor: VA Office of Research and Development
No Placebo Group
Trial Summary
What is the purpose of this trial?It is estimated that spinal cord injury (SCI) affects approximately 12,000 new individuals every year in the United States, with the majority are cervical and/or upper thoracic injuries. Despite this high prevalence of obstructive sleep apnea (OSA) in chronic SCI population minority of patients are treated and are adherent to standard therapy (CPAP). This proposal addresses a new therapeutic intervention for OSA in SCI. The investigators hypothesized that combined oropharyngeal and respiratory muscle exercises improve respiratory symptoms and alleviate OSA in patients with chronic SCI. The investigators will perform a pilot randomized, sham-controlled study to examine the impact of combined daily exercises (\~30 min) for 1 and 3 months durations among Veterans with SCI. The investigators believe that this novel approach to treating OSA and will yield significant new knowledge that improves the health and quality of life of these patients.
Eligibility Criteria
Participant Groups
2Treatment groups
Active Control
Placebo Group
Group I: Intervention exercise armActive Control1 Intervention
daily oropharyngeal and respiratory muscle exercises
Group II: Control armPlacebo Group1 Intervention
Daily sham exercises
Find A Clinic Near You
Research locations nearbySelect from list below to view details:
John D. Dingell VA Medical Center, Detroit, MIDetroit, MI
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Who is running the clinical trial?
VA Office of Research and DevelopmentLead Sponsor
Louis Stokes VA Medical CenterCollaborator