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Kinase Inhibitor

Sorafenib plus VT-122 for Hepatocellular Carcinoma

Phase 2
Waitlist Available
Research Sponsored by Vicus Therapeutics
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up up to 5 years
Awards & highlights
All Individual Drugs Already Approved
Approved for 5 Other Conditions

Summary

This trial is testing if VT-122, a combination of two drugs, can help patients with advanced liver cancer who have severe symptoms. The goal is to see if it can reduce inflammation and improve their ability to handle their main cancer treatment, possibly leading to better health and longer life.

Eligible Conditions
  • Hepatocellular Carcinoma

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~up to 5 years
This trial's timeline: 3 weeks for screening, Varies for treatment, and up to 5 years for reporting.

Treatment Details

Awards & Highlights

All Individual Drugs Already Approved
Therapies where all constituent drugs have already been approved are likely to have better-understood side effect profiles.
Approved for 5 Other Conditions
This treatment demonstrated efficacy for 5 other conditions.

Trial Design

2Treatment groups
Experimental Treatment
Placebo Group
Group I: Sorafenib plus VT-122Experimental Treatment2 Interventions
Group II: Sorafenib with placeboPlacebo Group2 Interventions
Participants randomized to the Control Arm (sorafenib with placebo) receive sorafenib as the standard of care, and placebo for the same periods as participants randomized to the Treatment Arm (sorafenib plus VT-122). Participants randomized to the Control Arm will undergo the same visits and procedures as would the participants randomized to the Treatment Arm.
Treatment
First Studied
Drug Approval Stage
How many patients have taken this drug
Sorafenib
FDA approved

Find a Location

Who is running the clinical trial?

Vicus TherapeuticsLead Sponsor
2 Previous Clinical Trials
72 Total Patients Enrolled
~1 spots leftby Dec 2025
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