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Anticholinergic

Clinical Study to Assess the Efficacy and Safety of AT-5214 in the Treatment of Subjects With Palmar Hyperhidrosis

Phase 2
Waitlist Available
Research Sponsored by Atacama Therapeutics
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Timeline
Screening 3 weeks
Treatment Varies
Follow Up week 6 (end of study)

Summary

This trial tests AT-5214 tablets on people with very sweaty palms to see if it can reduce their sweating. The study will compare two doses of the medication.

Eligible Conditions
  • Sweaty palms
  • Excessive Sweating

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~week 6 (end of study)
This trial's timeline: 3 weeks for screening, Varies for treatment, and week 6 (end of study) for reporting.

Treatment Details

Study Objectives

Study objectives can provide a clearer picture of what you can expect from a treatment.
Primary study objectives
PHIS Reduction
Secondary study objectives
Absolute change in PHIS
Absolute change of Sweat Production
Change in Sweat Production

Trial Design

3Treatment groups
Experimental Treatment
Placebo Group
Group I: Low Dose (2 mg)Experimental Treatment1 Intervention
Oral tablet containing 1 mg of active drug, dexmecamylamine HCl. Subjects will be instructed to take two tablets by mouth twice daily (in the morning and evening).
Group II: High Dose (4 mg)Experimental Treatment1 Intervention
Oral tablet containing 2 mg of active drug, dexmecamylamine HCl. Subjects will be instructed to take two tablets by mouth twice daily (in the morning and evening).
Group III: PlaceboPlacebo Group1 Intervention
Oral tablet containing no active drug. Subjects will be instructed to take two tablets by mouth twice daily (in the morning and evening).
Treatment
First Studied
Drug Approval Stage
How many patients have taken this drug
Dexmecamylamine
Not yet FDA approved

Find a Location

Who is running the clinical trial?

Atacama TherapeuticsLead Sponsor
1 Previous Clinical Trials
60 Total Patients Enrolled
~13 spots leftby Dec 2025
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