~6 spots leftby Mar 2026

Contrasting the Brain Effects of Risperidone and Invega With Functional Magnetic Resonance Imaging (fMRI) and Positron Emission Tomography (PET) Scanning

Palo Alto (17 mi)
Overseen bySteven G Potkin, M.D.
Age: 18 - 65
Sex: Any
Travel: May be covered
Time Reimbursement: Varies
Trial Phase: Phase 4
Waitlist Available
Sponsor: University of California, Irvine
No Placebo Group
Prior Safety Data

Trial Summary

What is the purpose of this trial?The purpose of this study is to better understand brain function and psychiatric and neurological illness when taking Invega or Risperdal. The objective is to compare the brain effects of Invega to Risperdal in patients with Schizophrenia. This comparison will be evaluated with PET imaging, fMRI, and neurological ratings and assessments.

Eligibility Criteria

Treatment Details

2Treatment groups
Experimental Treatment
Group I: RisperdalExperimental Treatment1 Intervention
Risperdal 2-8mg per day
Group II: InvegaExperimental Treatment1 Intervention
Invega 6-12mg per day

Find a clinic near you

Research locations nearbySelect from list below to view details:
UC IrvineIrvine, CA
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Who is running the clinical trial?

University of California, IrvineLead Sponsor
Janssen, LPIndustry Sponsor

References