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Laxative

Comparing 2L Bi-Pegyte to 4L PegLyte Regiments for Outpatient Colonic Preparation

N/A
Waitlist Available
Led By Robert A Enns, MD
Research Sponsored by University of British Columbia
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up 30 minutes
Awards & highlights
All Individual Drugs Already Approved
No Placebo-Only Group
Approved for 5 Other Conditions

Summary

The investigators wish to compare the efficacy and patient tolerability of a preparation consisting of 2L Bi-Peglyte plus 15mg of bisacodyl vs the standard preparation of 4L Peglyte. The investigators hypothesize that 2L Bi-Peglyte with 15mg bisacodyl will show higher efficacy and tolerability.

Eligible Conditions
  • No changes made.
  • Bowel Prep Efficacy

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~30 minutes
This trial's timeline: 3 weeks for screening, Varies for treatment, and 30 minutes for reporting.

Treatment Details

Study Objectives

Study objectives can provide a clearer picture of what you can expect from a treatment.
Primary study objectives
Difference in Boston Bowel Preparation Scale between the two groups
Secondary study objectives
Difference in the absolute number/percentage of participants in the two groups who find the bowel prep experience easy, acceptable, difficult, very difficult, or unable to complete.
Difference in the number of participants who develop distress symptoms from bowel prep (and the type) between the two groups

Awards & Highlights

All Individual Drugs Already Approved
Therapies where all constituent drugs have already been approved are likely to have better-understood side effect profiles.
No Placebo-Only Group
All patients enrolled in this study will receive some form of active treatment.
Approved for 5 Other Conditions
This treatment demonstrated efficacy for 5 other conditions.

Trial Design

2Treatment groups
Experimental Treatment
Active Control
Group I: 2L Bi-PeglyteExperimental Treatment1 Intervention
Subjects will be asked to take 2L Bi-Peglyte + 15mg bisacodyl for bowel prep the day before colonoscopy.
Group II: Standard bowel prepActive Control1 Intervention
Subject will receive standard bowel prep prior to colonoscopy.
Treatment
First Studied
Drug Approval Stage
How many patients have taken this drug
Bisacodyl
FDA approved

Find a Location

Who is running the clinical trial?

University of British ColumbiaLead Sponsor
1,476 Previous Clinical Trials
2,493,323 Total Patients Enrolled
Robert A Enns, MDPrincipal InvestigatorThe University of British Columbia
~22 spots leftby Dec 2025
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