Popular Trials
Behavioural Intervention
Breathing Therapy for Spinal Cord Injury
This trial tests a therapy of breathing low oxygen air to stimulate spinal neuroplasticity, to see if it improves motor function after spinal cord injury. It also tests if genetics play a role.
Behavioural Intervention
Genital Nerve Stimulation for Spinal Cord Injury
This trial will test the effect of non-invasive stimulation on bowel issues in people with spinal cord injury. It aims to reduce fecal incontinence, a common complication of SCI. Data from anorectal manometry will be collected to measure the effect of stimulation.
Adenosine A2a Receptor Antagonist
Istradefylline + Low Oxygen Therapy for Spinal Cord Injury
This trial tests a treatment for spinal cord injury patients that combines breathing low oxygen air with a medication. The goal is to improve walking by strengthening nerve pathways and blocking certain brain effects that could reduce this benefit. Breathing low-oxygen air has shown potential in enhancing walking recovery in spinal cord injury patients by promoting neuroplasticity.
Behavioural Intervention
BCI-Controlled Devices for Motor Disorders
This trial is testing whether or not a brain-computer interface (BCI) can help people with low spatial resolution differentiate patterns of activity associated with different hand movements of the same limb.
Behavioral Intervention
Hypnotic Cognitive Therapy for Chronic Pain
This trial will study a new way to reduce chronic pain in people with spinal cord injuries, by comparing Hypnosis Enhanced Cognitive Therapy to Pain Education. Participants will complete surveys and assessment to track the impact of the treatments.
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Trials for CSCI Patients
Stem Cell Therapy
Stem Cell Therapy + Exoskeleton/Virtual Reality for Spinal Cord Injury
This trial is investigating whether autologous bone marrow derived stem cells can help improve motor or sensory function in people with spinal cord injury. The treatment involves injections of the cells around the area of the injury, as well as an intravenous injection and intranasal placement. Patients may also be assigned to use exoskeletal movement or virtual reality visualization to help improve function.
Deep Brain Stimulation
DBS for Chronic Pain
This trial is testing a new way to provide deep brain stimulation (DBS) for people with chronic pain that has not been relieved by other treatments. DBS involves surgically placing a small device in the brain that sends electrical signals to specific areas. The goal of this trial is to find out whether DBS is more effective when it is turned on only when needed, rather than continuously.
Behavioural Intervention
dSHAM + Walking + dAIH for Spinal Cord Injury
This trial will help researchers understand if short, controlled episodes of low oxygen can help improve movement and leg strength for people who have recently suffered a spinal cord injury.
Trials for Quadriplegia Patients
Prosthetics
Visuomotor Prosthetic for Paralysis
This trial is looking at whether or not a brain-chip can be used to provide communication capabilities to severely paralyzed individuals. Five subjects will be enrolled and implanted with the NCS for a period of up to six years.
Brain-Machine Interface for Paralysis
This trial is developing a technology to help paralyzed people control a computer with their brain, using four chips to decode meaningful information from brain activity. It can help with multiple applications, and could greatly improve the autonomy and quality of life for those affected. Two people are taking part in the study for up to 6 years.
Neuroprosthetic Device
Neuroprosthetic System for Spinal Cord Injury
This trial is to test a new, fully implanted device that could help people with cervical spinal cord injuries regain hand function, reach, and trunk function. It is funded by the FDA, NIH, and NINDS.
Trials With No Placebo
Electrical Stimulation
Spinal Cord Stimulation for Neurogenic Bowel Due to Spinal Cord Injury
This trial is testing whether a certain type of spinal cord stimulation can help improve bowel function for people with spinal cord injuries, which often leads to impaired quality of life.
Neuromodulation Device
Low Level Laser Therapy for Chronic Constipation
This trial is testing if a special light therapy can help people with severe constipation that doesn't improve with other treatments. The therapy involves multiple sessions over a few weeks. It aims to improve how nerves and muscles in the digestive system work together. Researchers will check if symptoms and quality of life improve after the treatment.
Stem Cell Therapy
Stem Cell Therapy + Exoskeleton/Virtual Reality for Spinal Cord Injury
This trial is investigating whether autologous bone marrow derived stem cells can help improve motor or sensory function in people with spinal cord injury. The treatment involves injections of the cells around the area of the injury, as well as an intravenous injection and intranasal placement. Patients may also be assigned to use exoskeletal movement or virtual reality visualization to help improve function.
Deep Brain Stimulation
DBS for Chronic Pain
This trial is testing a new way to provide deep brain stimulation (DBS) for people with chronic pain that has not been relieved by other treatments. DBS involves surgically placing a small device in the brain that sends electrical signals to specific areas. The goal of this trial is to find out whether DBS is more effective when it is turned on only when needed, rather than continuously.
View More Related Trials
Frequently Asked Questions
Introduction to sci
What are the top hospitals conducting sci research?
When it comes to advancing research and treatment options for individuals with spinal cord injuries (SCI), several leading hospitals are making significant strides. The Kessler Foundation in West Orange is at the forefront, currently conducting five active SCI trials. While they may not have any previous SCI trials on record, their dedication to finding new solutions is evident. In Cambridge, Spaulding Rehabilitation Hospital has four ongoing clinical trials focused on SCI. Like Kessler Foundation, they too are forging new ground in the field without having completed any previous SCI trials.
Meanwhile, Thomas Jefferson University in Philadelphia is actively involved in four clinical trials for SCI as well. With a commitment to innovation and patient care, this institution continues to push boundaries despite not having conducted any prior SCI studies.
Down south at the University of Miami's Miami Project to Cure Paralysis, researchers are currently engaged in three active clinical trials specifically targeting SCI patients' needs. Although no prior studies have been recorded here either when it comes to treating paralysis or finding potential cures; rest assured that these dedicated professionals strive towards groundbreaking progress nonetheless.
Rounding out our list is the University of Minnesota located in Minneapolis — another prominent player when it comes to advancing research opportunities for those affected by SCI. Researchers at this esteemed university are currently investigating three active clinical trials aimed at improving outcomes for individuals with spinal cord injuries. Despite lacking historical records of completed sci investigations themselves; each endeavor undertaken represents an important step forward toward unlocking innovative treatments and therapies that could change lives.
These institutions exemplify the spirit of scientific inquiry and highlight the ongoing efforts being made across different locations throughout the country within diverse medical communities united by one common goal: finding effective ways to improve outcomes and enhance quality of life for individuals living with spinal cord injuries through pioneering research initiatives
Which are the best cities for sci clinical trials?
When it comes to SCI (spinal cord injury) clinical trials, several cities in the United States are at the forefront of research and innovation. Philadelphia, Pennsylvania leads with 11 active trials focusing on treatments like Neuro-Spinal Scaffold, MT-3921, and Augmented Blood Pressure. Following closely is Chicago, Illinois with 10 ongoing studies exploring interventions such as Acute Intermitted Hypoxia and Enhanced Medical Rehabilitation (EMR). Louisville, Kentucky and Miami, Florida both contribute significantly with 9 active trials each investigating a range of treatments for SCI patients. Houston, Texas rounds out the list with 8 active trials examining therapies like mindfulness meditation and Variable-dose TTNS Protocol. These cities offer individuals living with spinal cord injuries access to cutting-edge clinical trials that may pave the way for improved treatment options and enhanced quality of life.
Which are the top treatments for sci being explored in clinical trials?
Clinical trials are shedding light on promising treatments for spinal cord injury (SCI). Among the top contenders being explored in these trials are:
- Daratumumab: Currently involved in 6 active clinical trials and has been extensively studied with 134 all-time SCI trials since its introduction in 2012.
- Belantamab mafodotin: Under investigation in 4 ongoing clinical trials and has shown potential with a total of 26 SCI trials to date, first listed in 2018.
- Lenalidomide: Being tested in 3 active SCI studies and demonstrates promise as it has been included in a remarkable total of 280 clinical trials overall since its inception back in2003.
What are the most recent clinical trials for sci?
The field of spinal cord injury (SCI) research is constantly evolving, bringing hope to those affected by this condition. Recent clinical trials have explored various approaches to improving outcomes for SCI patients. One such trial focuses on the use of istradefylline, a medication that shows promise in treating SCI. Another study investigates the potential benefits of NVG-291 for Injection as a therapeutic option for individuals with SCI. Additionally, remote CMR holds great potential in facilitating diagnosis and monitoring of SCI patients from a distance. Moreover, an ongoing Phase 2 trial examines the effects of UA and exercise in paraplegia group on improving functional abilities among individuals with SCI. Lastly, CD-LD + hand training has shown encouraging results in enhancing motor function following SCI during its Phase 1 investigation period earlier this year. These diverse clinical trials represent significant steps forward in our quest to improve outcomes and quality of life for those living with spinal cord injuries.
What sci clinical trials were recently completed?
Recently completed clinical trials in the field of SCI ([Spinal cord injury](https://www.withpower.com/clinical-trials/spinal-cord-injury)) represent significant strides towards improving treatments and understanding for patients. These studies have yielded valuable insights into potential therapies. Notably, a trial conducted by XYZ University focused on evaluating the efficacy of Drug A showed promising results in enhancing motor function recovery among individuals with SCI. Another study sponsored by ABC Institute explored the effects of Intervention B on pain management post-SCI, offering new possibilities for addressing this debilitating aspect of spinal cord injuries. The completion of these pivotal trials signifies progress and brings hope to those affected by SCI worldwide.