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Corticosteroid

Assessing the Cortical Response to Noxious and Auditory Stimuli Using Near Infrared Spectroscopy in Subjects Under General Anesthesia

N/A
Waitlist Available
Led By Barry D Kussman, MBBCh
Research Sponsored by Boston Children's Hospital
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be younger than 65 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up up to 5 years
Awards & highlights
Approved for 5 Other Conditions
All Individual Drugs Already Approved

Summary

The primary aim is to utilize near-infrared spectroscopy (NIRS) in patients under general anesthesia to measure changes in brain blood flow in the bilateral somatosensory cortices and the prefrontal cortices in response to noxious stimulation.

Eligible Conditions
  • Anesthesia
  • Pain

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~up to 5 years
This trial's timeline: 3 weeks for screening, Varies for treatment, and up to 5 years for reporting.

Treatment Details

Awards & Highlights

Approved for 5 Other Conditions
This treatment demonstrated efficacy for 5 other conditions.
All Individual Drugs Already Approved
Therapies where all constituent drugs have already been approved are likely to have better-understood side effect profiles.

Trial Design

3Treatment groups
Active Control
Placebo Group
Group I: Drug lower doseActive Control1 Intervention
Remifentanil infusion
Group II: Drug higher doseActive Control1 Intervention
Remifentanil infusion
Group III: PlaceboPlacebo Group1 Intervention
Normal saline infusion

Find a Location

Who is running the clinical trial?

Boston Children's HospitalLead Sponsor
788 Previous Clinical Trials
5,582,517 Total Patients Enrolled
Barry D Kussman, MBBChPrincipal InvestigatorBoston Children's Hospital
~6 spots leftby Dec 2025