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Procedure

Inter-fascial Plane Between the SArtorius Muscle and FEmoral Artery (ISAFE) (ISAFE Trial)

N/A
Waitlist Available
Research Sponsored by University of Toronto
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up 24 and 48 hours
Awards & highlights
No Placebo-Only Group

Summary

This trial tests a new method for placing a pain relief tube in patients undergoing knee replacement surgery. The new method aims to provide better and longer-lasting pain relief by positioning the tube between a thigh muscle and an artery. This placement helps keep the tube in place and avoids complications.

Eligible Conditions
  • Conduction Anesthesia
  • Knee Replacement Surgery

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~24 and 48 hours
This trial's timeline: 3 weeks for screening, Varies for treatment, and 24 and 48 hours for reporting.

Treatment Details

Study Objectives

Study objectives can provide a clearer picture of what you can expect from a treatment.
Primary study objectives
Catheter dislodgement
Secondary study objectives
Incidence of catheter insertion related complications
Incidence of sensory block
Number of attempts for catheter insertion
+4 more

Awards & Highlights

No Placebo-Only Group
All patients enrolled in this study will receive some form of active treatment.

Trial Design

2Treatment groups
Experimental Treatment
Active Control
Group I: ISAFE techniqueExperimental Treatment1 Intervention
Adductor canal block catheter tip located in the fascial plane between sartorious muscle and femoral artery.
Group II: Conventional techniqueActive Control1 Intervention
Adductor canal block catheter tip located in lateral to the femoral artery.

Find a Location

Who is running the clinical trial?

University of TorontoLead Sponsor
725 Previous Clinical Trials
1,115,596 Total Patients Enrolled
Mount Sinai Hospital, CanadaOTHER
204 Previous Clinical Trials
69,097 Total Patients Enrolled
Yehoshua Gleicher, MD, MScStudy ChairUniversity of Toronto
~28 spots leftby Dec 2025
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