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ScopeGuide-assisted colonoscopy for Iron-Deficiency Anemia

N/A
Waitlist Available
Led By Christopher W Teshima, MD FRCPC
Research Sponsored by Christopher Teshima
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up 1 day (immediate outcome assessment at time of endoscopy procedure)
Awards & highlights
No Placebo-Only Group

Summary

Colonoscopy is an established technology that enables doctors to obtain live video from inside patients' large intestines, which is essential for the diagnosis of numerous intestinal illnesses. It consists of a long, flexible tube fitted with a light-source and small video camera that transmits the images onto a display monitor. The doctor inserts the scope into the anus, moves it into the rectum and then guides it slowly through the entire colon. Because of the various twists and turns that are part of normal bowel anatomy, advancing the scope through the entire colon is not always successful and can become challenging when the scope forms loops inside the abdomen. Unfortunately, there is no way for the doctor to see the shape of the scope inside the body other than what is seen from the video at its front end, and so navigating the colon relies on instinct accumulated with experience and the "feel" of the scope as loops begin to form. This is important because not only can this loop formation cause pain, but it can also increase the likelihood of an incomplete test. Incomplete tests matter because a major reason for performing colonoscopy is colon cancer screening and surveillance; detecting early cancers at treatable stages and looking for polyps that may be pre-cancerous growths. When colonoscopy does not advance through the entire colon, parts are left unexamined where cancer may develop. A new technology called "ScopeGuide" has been developed that uses magnetic coils embedded within the scope to create a 3D image of the shape of the entire scope inside the body that is projected onto the monitor for the doctor to see. This will show if loops are forming and will provide information about how to eliminate loops once they have formed. In this research study, the investigators will compare colonoscopy with the assistance of ScopeGuide to colonoscopy performed in the standard fashion, to see if ScopeGuide results in more successful procedures that are easier for the doctor and more comfortable for patients.

Eligible Conditions
  • Iron-Deficiency Anemia
  • Diarrhea
  • Colon Cancer
  • Traveler's Diarrhea
  • Colorectal Cancer

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~1 day (immediate outcome assessment at time of endoscopy procedure)
This trial's timeline: 3 weeks for screening, Varies for treatment, and 1 day (immediate outcome assessment at time of endoscopy procedure) for reporting.

Treatment Details

Study Objectives

Study objectives can provide a clearer picture of what you can expect from a treatment.
Primary study objectives
Sedation Score
Secondary study objectives
Ancillary maneuvers to facilitate procedure
Cecal intubation rate
Patient comfort
+1 more

Awards & Highlights

No Placebo-Only Group
All patients enrolled in this study will receive some form of active treatment.

Trial Design

2Treatment groups
Experimental Treatment
Active Control
Group I: ScopeGuide-assisted colonoscopyExperimental Treatment1 Intervention
These patients will undergo colonoscopy with the assistance of the Olympus ScopeGuide system.
Group II: Conventional colonoscopyActive Control1 Intervention
These patients will undergo colonoscopy identical to that in the intervention arm, except with endoscopes lacking the ScopeGuide system.
Treatment
First Studied
Drug Approval Stage
How many patients have taken this drug
Olympus ScopeGuide
2011
N/A
~250

Find a Location

Who is running the clinical trial?

Christopher TeshimaLead Sponsor
Christopher W Teshima, MD FRCPCPrincipal InvestigatorUniversity of Alberta
~18 spots leftby Nov 2025