Epidural Electrical Stimulation for Spinal Cord Disorders

N/A

Recruiting

Research Sponsored by University of California, Los Angeles

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

Any patients undergoing brain or spinal cord surgery where spinal neuromonitoring is utilized.

Be older than 18 years old

Timeline

Screening 3 weeks

Treatment Varies

Follow Up during intraoperative surgery during stimulation and within 2 minutes after stimulation

Awards & highlights

No Placebo-Only Group

Summary

This trial will test whether electrical stimulation of the spinal cord can help people with respiratory depression from an opioid overdose.

Who is the study for?

This trial is for patients who are undergoing brain or spinal cord surgery and where monitoring of the spinal cord's activity is used. There are no specific exclusion criteria, so it appears open to all eligible surgical candidates.

What is being tested?

The study tests if epidural electrical stimulation (EES) at the cervical spine can counteract opioid-induced breathing problems during surgery. It will record how EES affects motor activity and respiratory function in human patients.

What are the potential side effects?

While not explicitly stated, potential side effects may include discomfort from the stimulation, temporary nerve issues, or skin irritation at the electrode site.

Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below

Select...

I am having brain or spinal surgery with monitoring.

Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ during intraoperative surgery during stimulation and within 2 minutes after stimulation

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~during intraoperative surgery during stimulation and within 2 minutes after stimulation

This trial's timeline: 3 weeks for screening, Varies for treatment, and during intraoperative surgery during stimulation and within 2 minutes after stimulation for reporting.