Synbiotic+ for Gastrointestinal Disorders
(SYN Trial)

Recruiting in Palo Alto (17 mi)

Age: 18+

Sex: Female

Travel: May Be Covered

Time Reimbursement: Varies

Trial Phase: Academic

Waitlist Available

Sponsor: Colorado State University

Trial Summary

What is the purpose of this trial?The aim of this study is to determine how regular consumption of Synbiotic+, a dietary supplement that contains prebiotics, probiotics, and postbiotics, impacts functional gastrointestinal health, markers of intestinal inflammation and immune health, and influences mood and behavior. The primary outcome will be to assess gastrointestinal health using bowel movement tracking, self-report and objective assessments of gastrointestinal symptom severity, stool levels of short chain fatty acids, changes in the gut microbiota, including recovery of LGG and BB-12, and functional measures of the microbiome. Secondary outcomes will include stool and blood markers of gut barrier function and intestinal inflammation, immune health, and self-assessments of stress, anxiety, sleep, and quality of life.

Eligibility Criteria

This trial is for women experiencing gastrointestinal issues or benign liver and biliary diseases. Participants should be interested in how dietary supplements might affect their gut health, mood, and behavior.

Inclusion Criteria

I am willing to follow the study rules and go to all clinic visits.

I am a healthy woman aged between 25 and 65.

BMI <30

+1 more

Exclusion Criteria

I am under 25 or over 65 years old.

BMI >30

Pregnant and breastfeeding individuals

+5 more

Participant Groups

The study tests Synbiotic+, a supplement with prebiotics, probiotics, and postbiotics. It looks at its effect on bowel movements, GI symptoms, gut microbes, inflammation markers in stool/blood, immune health, stress levels, sleep quality & overall life satisfaction.

2Treatment groups

Experimental Treatment

Placebo Group

Group I: Treatment Group (probiotic supplement)Experimental Treatment1 Intervention

This group will take a once daily supplement containing pre-pro-post biotics.

Group II: ControlPlacebo Group1 Intervention

This group will be taking a once daily placebo pill.