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Diet Modification for Obesity (WYE Trial)
N/A
Recruiting
Led By Ellen A Schur, MD, MS
Research Sponsored by University of Washington
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial Must have
Be between 18 and 65 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up 7 days of diet intervention
Awards & highlights
No Placebo-Only Group
Summary
This trial explores how nutrition affects the brain and how it could lead to obesity. It uses MRI to study the hypothalamus.
Who is the study for?
This trial is for overweight individuals aged 20-40 with a BMI of 25-29.9, willing to try a new diet for two weeks and undergo MRI scans. It's not suitable for those with major health issues, metal implants, extreme diets like veganism, or who are pregnant.
What is being tested?
The study tests how three different diet modifications affect brain inflammation related to obesity by using MRI scans of the hypothalamus over a period of 14 days.
What are the potential side effects?
Since this trial involves dietary changes rather than medication, side effects may include typical reactions to diet adjustment such as changes in energy levels, mood swings, or digestive discomfort.
Timeline
Screening ~ 3 weeks3 visits
Treatment ~ Varies
Follow Up ~ 7 days of diet intervention
Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~7 days of diet intervention
Treatment Details
Study Objectives
Study objectives can provide a clearer picture of what you can expect from a treatment.Primary study objectives
Hypothalamic Gliosis
Awards & Highlights
No Placebo-Only Group
All patients enrolled in this study will receive some form of active treatment.
Trial Design
3Treatment groups
Experimental Treatment
Group I: Assigned Diet #3Experimental Treatment1 Intervention
Group II: Assigned Diet #2Experimental Treatment1 Intervention
Group III: Assigned Diet #1Experimental Treatment1 Intervention
Find a Location
Who is running the clinical trial?
University of WashingtonLead Sponsor
1,829 Previous Clinical Trials
1,907,052 Total Patients Enrolled
2 Trials studying Gliosis
214 Patients Enrolled for Gliosis
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)NIH
2,463 Previous Clinical Trials
4,337,361 Total Patients Enrolled
2 Trials studying Gliosis
214 Patients Enrolled for Gliosis
Ellen A Schur, MD, MSPrincipal InvestigatorUniversity of Washington
1 Previous Clinical Trials
102 Total Patients Enrolled
1 Trials studying Gliosis
102 Patients Enrolled for Gliosis
Media Library
Eligibility Criteria:
This trial includes the following eligibility criteria:- I have anemia or problems with my kidney or liver.I am currently pregnant, going through menopause, or breastfeeding.I am currently taking medication for weight loss or to change my appetite.I have had weight-loss surgery or am actively trying to lose weight.I have gallbladder disease or gallstones.I have a major medical condition like diabetes or multiple sclerosis.I am between 20 and 40 years old.
Research Study Groups:
This trial has the following groups:- Group 1: Assigned Diet #1
- Group 2: Assigned Diet #3
- Group 3: Assigned Diet #2
Awards:
This trial has 1 awards, including:- No Placebo-Only Group - All patients enrolled in this study will receive some form of active treatment.
Timeline:
This trial has the following timeline:- Screening: It may take up to 3 Weeks to process to see if you qualify in this trial.
- Treatment: The duration you will receive the treatment varies.
- Follow Ups: You may be asked to continue sharing information regarding the trial for 6 Months after you stop receiving the treatment.