← Back to Search

Compression Stockings

Compression Stockings for Congestive Heart Failure (ROCK-HF Trial)

N/A
Recruiting
Research Sponsored by University of Maryland, Baltimore
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up 3 months

Summary

"This trial is looking at whether tight compression socks or soft compression socks are more effective in preventing swelling and skin changes in patients with congestive heart failure. Participants will be randomly assigned to wear either type of

Who is the study for?
This trial is for heart failure patients experiencing leg swelling and potential skin changes due to fluid buildup. Participants must be able to wear compression stockings daily and attend both in-person and virtual check-ups. Those with poor kidney function affecting diuretic use may also join.
What is being tested?
The study tests if knee-high tight socks (high-grade compression) versus soft socks (low-grade compression) can prevent leg swelling without worsening heart failure symptoms. It involves routine medical tests, wearing the assigned stockings, and follow-up visits over three months.
What are the potential side effects?
Potential side effects include discomfort or skin irritation from the stockings. There's a small risk that increased pressure on the legs could push fluids back towards the heart, possibly exacerbating heart failure symptoms.

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~3 months
This trial's timeline: 3 weeks for screening, Varies for treatment, and 3 months for reporting.

Treatment Details

Study Objectives

Study objectives can provide a clearer picture of what you can expect from a treatment.
Primary study objectives
Change in kidney function.
Change in symptoms of heart failure.
Incidence of adverse events.
Secondary study objectives
Change in C Class from the CEAP classification for venous insufficiency.
Change in venous reflux.
Mobility of the patient

Trial Design

2Treatment groups
Experimental Treatment
Placebo Group
Group I: high grade compression stocking armExperimental Treatment1 Intervention
Patients will be assigned to receive 2 pairs of high grade compression stockings (20-30 mmHg), that they will be wearing at least 8 hours a day 5 days a week.
Group II: low grade compression stocking armPlacebo Group1 Intervention
Patients will be assigned to receive 2 pairs of low grade compression stockings (10-15 mmHg), that they will be wearing at least 8 hours a day 5 days a week.

Find a Location

Who is running the clinical trial?

National Institute on Aging (NIA)NIH
1,782 Previous Clinical Trials
28,184,043 Total Patients Enrolled
University of Maryland, BaltimoreLead Sponsor
711 Previous Clinical Trials
379,189 Total Patients Enrolled
University of Texas Southwestern Medical CenterOTHER
1,079 Previous Clinical Trials
1,056,114 Total Patients Enrolled
~22 spots leftby Jun 2025
Unbiased ResultsWe believe in providing patients with all the options.
Your Data Stays Your DataWe only share your information with the clinical trials you're trying to access.
Verified Trials OnlyAll of our trials are run by licensed doctors, researchers, and healthcare companies.
Back to top