Your session is about to expire
← Back to Search
Cure Therapies for HIV
N/A
Waitlist Available
Led By Francesca Cossarini, MD
Research Sponsored by Icahn School of Medicine at Mount Sinai
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial Must have
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up end of the study (at month one) compared to baseline
Awards & highlights
No Placebo-Only Group
Summary
This trial will test if HIV cure therapies can reduce virus levels in the gut and change the immune system there.
Who is the study for?
This trial is for adults aged 18-75 with chronic HIV infection who are willing to follow the study procedures. They must be able to undergo a colonoscopy twice and be on a treatment that might cure HIV. People with bowel diseases, other gastrointestinal conditions, coagulation problems, or those pregnant or planning pregnancy can't participate.
What is being tested?
The study aims to see if therapies thought to potentially cure HIV can change immune cells in the gut and lower tissue-associated HIV levels. Participants will have their gastrointestinal tract examined through a colonoscopy before and after receiving these potential cure therapies.
What are the potential side effects?
While not directly related to medication side effects, undergoing a colonoscopy may cause discomfort, bloating, cramps or rarely more serious complications like bleeding or perforation of the colon.
Timeline
Screening ~ 3 weeks3 visits
Treatment ~ Varies
Follow Up ~ end of the study (at month one) compared to baseline
Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~end of the study (at month one) compared to baseline
Treatment Details
Study Objectives
Study objectives can provide a clearer picture of what you can expect from a treatment.Primary study objectives
Change in HIV tissue viral load
Secondary study objectives
Change in number of Cytotoxic T cells
Change in number of NK Cells
Awards & Highlights
No Placebo-Only Group
All patients enrolled in this study will receive some form of active treatment.
Trial Design
1Treatment groups
Experimental Treatment
Group I: Patients with HIV TherapyExperimental Treatment1 Intervention
Subjects receiving therapies with the potential for HIV cure
Treatment
First Studied
Drug Approval Stage
How many patients have taken this drug
Colonoscopy
2012
Completed Phase 3
~115560
Find a Location
Who is running the clinical trial?
Icahn School of Medicine at Mount SinaiLead Sponsor
914 Previous Clinical Trials
572,895 Total Patients Enrolled
Francesca Cossarini, MDPrincipal InvestigatorIcahn School of Medicine at Mount Sinai
Media Library
Eligibility Criteria:
This trial includes the following eligibility criteria:- I currently have a sexually transmitted infection.I am willing and able to follow the study's requirements.I am between 18 and 75 years old.I am currently being treated with a drug that could potentially cure HIV.I have a condition affecting my gut that changes the lining of my intestines.I am willing and able to have two colonoscopies during the study.
Research Study Groups:
This trial has the following groups:- Group 1: Patients with HIV Therapy
Awards:
This trial has 1 awards, including:- No Placebo-Only Group - All patients enrolled in this study will receive some form of active treatment.
Timeline:
This trial has the following timeline:- Screening: It may take up to 3 Weeks to process to see if you qualify in this trial.
- Treatment: The duration you will receive the treatment varies.
- Follow Ups: You may be asked to continue sharing information regarding the trial for 6 Months after you stop receiving the treatment.