Cell Free DNA Testing for Myocarditis
This trial is looking at a potential new way to diagnose active myocarditis (inflammation of the heart) in patients with sarcoidosis. The current method for diagnosing active myocarditis is limited and this trial is exploring whether cell free DNA (fragments of genomic DNA that are released into the circulation from dying or damaged cells) can be used as a biomarker to more accurately diagnose active myocarditis.
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Introduction to myocarditis
What are the top hospitals conducting myocarditis research?
In the realm of clinical trials for myocarditis, several hospitals are leading the charge in research and innovation. One such institution is the world-renowned Cleveland Clinic located in Cleveland, Ohio. Currently, they have two active myocarditis trials underway, with a total of two completed studies since their first recorded trial in 2022. Similarly dedicated to advancing knowledge about this condition is Virginia Commonwealth University in Richmond. With two ongoing myocarditis trials and a history of two previously conducted studies dating back to 2021, this university plays an essential role in shaping future treatment options.
Moving eastward to Boston, Massachusetts General Hospital stands at the forefront of cardiovascular research once again. While currently focusing on a single active myocarditis trial, their commitment extends beyond that with one completed study already under their belt from 2022. Additionally contributing to the cause is Brigham and Women's Hospital also situated within Boston's esteemed medical landscape; boasting one ongoing trial along with successfully conducting another investigation during 2022.
Lastly, we turn our attention to Ann Arbor where the University of Michigan has made noteworthy strides in understanding and combatting myocarditis as well. This institution presently engages in one active clinical trial while having accomplished a former investigation earlier this year 2022 further illuminating potential paths for improved management strategies.
These hospitals' dedication to investigating new treatments for myocarditis showcases both their commitment to patient care and their contributions towards critical advancements within cardiovascular medicine as a whole
Which are the best cities for myocarditis clinical trials?
When it comes to myocarditis clinical trials, several cities are at the forefront of research. Boston, Massachusetts leads with 6 active trials exploring treatments like Abatacept plus and CardiolRx for myocarditis/pericarditis following COVID-19 or MIS-C. Houston, Texas follows closely behind with 4 ongoing studies focused on interventions such as Abatacept plus and Methylprednisolone for myocarditis/pericarditis after COVID-19 or MIS-C. Los Angeles, California, Salt Lake City, Utah, and Indianapolis, Indiana also contribute to the field with their respective investigations into myocarditis/pericarditis following COVID-19 or MIS-C along with potential treatment options like Abatacept plus. These cities offer individuals affected by myocarditis access to cutting-edge clinical trials that may pave the way for improved care in the future.
Which are the top treatments for myocarditis being explored in clinical trials?
Exciting developments are underway in the field of myocarditis treatment, with several standout contenders currently being explored in clinical trials. Among them:
- Abatacept plus: This promising combination therapy is involved in one active trial and represents a new player on the scene since its listing in 2022.
- CardiolRx: Another newcomer to the field, CardiolRx has also caught researchers' attention, participating in one ongoing trial for myocarditis since its introduction this year.
- Methylprednisolone: With evidence supporting its effectiveness as an anti-inflammatory agent, methylprednisolone enters the spotlight with one active trial dedicated to exploring its potential benefits for treating myocarditis.
- Cell-free DNA: Leveraging cutting-edge technology and insights from genetics research, cell-free DNA shows promise as it undergoes investigation through one active cardiovascular trial. These treatments hold hope for improving outcomes and transforming the landscape of myocarditis management.
What are the most recent clinical trials for myocarditis?
Recent clinical trials have yielded promising results in the field of myocarditis, offering potential advancements in treatment options. One notable trial examined the use of abatacept as an adjunct therapy for individuals with myocarditis, demonstrating encouraging outcomes in Phase 3. Additionally, CardiolRx showcased positive developments during its Phase 2 trial. Another study explored methylprednisolone's effectiveness as a treatment option for myocarditis patients in Phase 3. Lastly, research focused on understanding and managing cases of myocarditis/pericarditis following COVID-19 or MIS-C has entered into Phase 4 studies. These groundbreaking trials bring new hope to those affected by this condition and may lead to improved strategies for diagnosis and management moving forward.
What myocarditis clinical trials were recently completed?
Recently, several clinical trials focusing on myocarditis have made significant progress in advancing our understanding and treatment of this condition. Notably, a trial sponsored by the National Heart, Lung, and Blood Institute (NHLBI) was recently completed. This study aimed to investigate potential interventions for myocarditis and provide valuable insights into improving patient outcomes. The completion of such trials underscores the commitment of researchers to combatting this cardiac inflammatory disorder and brings hope for better management strategies in the future.