← Back to Search

Probiotic

Probiotics for Chronic Pain

N/A

Waitlist Available

Research Sponsored by Medical College of Wisconsin

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

13-17 years of age

Body Mass Index ≥85th percentile for sex and age

Must not have

Females who are pregnant or lactating

Timeline

Screening 3 weeks

Treatment Varies

Follow Up 7-11 weeks

Awards & highlights

No Placebo-Only Group

Summary

This trial is testing whether a probiotic can help reduce pain in obese teens.

Who is the study for?

This trial is for young people aged 13-17 who are experiencing chronic pain, have a BMI in the 85th percentile or higher, and do not use drugs that affect gut function or inflammation. It's not for those on recent antibiotics/probiotics, with severe inflammatory diseases (except certain thyroid/asthma conditions), poor reactions to needles, pregnant/lactating females, or any condition that could interfere with the study.

What is being tested?

The trial is testing if Lactobacillus Plantarum, a type of probiotic, can help reduce inflammation and manage chronic pain in overweight adolescents. Participants will be given this probiotic to see if it has beneficial effects.

What are the potential side effects?

Probiotics like Lactobacillus Plantarum are generally considered safe but may cause digestive discomfort such as gas or bloating initially. Rarely they might lead to infection in individuals with underlying health issues.

Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below

Select...

I am between 13 and 17 years old.

Select...

My BMI is in the top 15% for my age and sex.

Exclusion Criteria

You may be eligible for the trial if you check “No” for criteria below:

Select...

I am not pregnant or breastfeeding.

Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ 7-11 weeks

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~7-11 weeks

This trial's timeline: 3 weeks for screening, Varies for treatment, and 7-11 weeks for reporting.

Treatment Details

Study Objectives

Study objectives can provide a clearer picture of what you can expect from a treatment.

Primary study objectives

Change in systemic inflammation - CRP

Secondary study objectives

Change in Worst Pain intensity

Awards & Highlights

No Placebo-Only Group

All patients enrolled in this study will receive some form of active treatment.

Trial Design

1Treatment groups

Experimental Treatment

Group I: ProbioticExperimental Treatment1 Intervention

Participants will be given the probiotic supplement Lp299v. The supplement is taken by mouth in the form of capsules. Participants will undergo a screening visit. After 7-11 weeks of taking Lp299v, they will return for their final visit. Blood will be drawn before and after the 7- 11 week intervention.

0 / 3Eligibility criteria met