What side effects are associated with this type of intervention?

The most common side effects of dental implants, particularly those involving immediate loading with a provisional prosthesis, include pain, swelling, and bruising at the implant site. There may also be a risk of infection, which can be mitigated with proper oral hygiene and post-operative care. In some cases, patients might experience temporary numbness or tingling due to nerve irritation. Long-term complications can include implant failure or peri-implantitis, an inflammatory condition affecting the soft and hard tissues around the implant.

What prior FDA approvals exist?

FDA-approved treatments for toothless jaws often involve dental implants, which are titanium posts surgically placed into the jawbone to serve as artificial tooth roots. One common approach is immediate loading with a provisional prosthesis, where a temporary crown is placed on the implant shortly after surgery. This method allows for quicker restoration of function and aesthetics. While specific FDA approvals for individual implant systems may vary, popular systems include those from companies like Nobel Biocare, Straumann, and Dentsply Sirona, which have undergone rigorous testing to ensure safety and efficacy.

What other types of research exist?

Promising alternatives to dental implants with immediate loading for toothless jaw patients include: 1) All-on-4 dental implants, which use four strategically placed implants to support a full arch prosthesis, providing immediate function and aesthetics. 2) Zygomatic implants, which anchor in the cheekbone and are suitable for patients with severe bone loss in the upper jaw. 3) Removable implant-supported overdentures, which offer a more cost-effective and less invasive option while still providing stability and improved function compared to traditional dentures. 4) Advanced bone grafting techniques and tissue engineering, which enhance the success of implant placement in patients with insufficient bone structure.

← Back to Search

Dental Implant

Eztetic Dental Implants for Toothless Jaw (RoseQuartz Trial)

N/A

Waitlist Available

Led By Burak Yilmaz, DDS

Research Sponsored by Zimmer Biomet

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

Be older than 18 years old

Timeline

Screening 3 weeks

Treatment Varies

Follow Up 2 years

Awards & highlights

No Placebo-Only Group

Summary

This trial involves using Eztetic dental implants to replace missing teeth in the front part of the upper or lower jaw. It targets patients needing single tooth replacements with stable back teeth. The implant serves as a root, with a temporary crown shaping the gum and a permanent crown placed after healing.

Who is the study for?

Adults with a toothless jaw who need dental implants in the front part of their mouth. They must have good bone stability, enough jaw width, and healthy gums. Smokers or those with certain health issues like uncontrolled diabetes, heart disease, severe periodontal disease, or infections are not eligible.

What is being tested?

The Eztetic Dental Implant System is being tested for people needing teeth replaced in the front lower or upper jaw. The study observes immediate loading of temporary crowns after implant surgery and final restorations within 6 months.

What are the potential side effects?

Potential side effects may include discomfort at the implant site, swelling, bruising, bleeding during and after surgery; there's also a risk of infection or implant failure which could require additional treatment.

Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ 2 years

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~2 years

This trial's timeline: 3 weeks for screening, Varies for treatment, and 2 years for reporting.

Treatment Details

Study Objectives

Study objectives can provide a clearer picture of what you can expect from a treatment.

Primary study objectives

Implant survival

Secondary study objectives

Marginal bone changes

Awards & Highlights

No Placebo-Only Group

All patients enrolled in this study will receive some form of active treatment.

Trial Design

1Treatment groups

Experimental Treatment

Group I: Eztetic dental implantExperimental Treatment1 Intervention

Eztetic 3.1mm diameter, lengths 8, 10, 11.5, 13, 16 mm

Treatment

First Studied

Drug Approval Stage

How many patients have taken this drug

Eztetic dental implant

2019

N/A

~90

Do I qualify?Apply below to find out

Research Highlights

Information in this section is not a recommendation. We encourage patients to speak with their healthcare team when evaluating any treatment decision.

Mechanism Of Action

Side Effect Profile

Prior Approvals

Other Research

The most common treatment for a toothless jaw, particularly using dental implants with immediate loading, involves the process of osseointegration. This is where the implant integrates with the jawbone, creating a stable and durable foundation for the prosthesis. Immediate loading with a provisional prosthesis allows for the restoration of function and aesthetics soon after the implant placement, which is essential for improving the patient's quality of life. This approach reduces the waiting time for final restorations and helps maintain the structure and health of the jawbone, preventing bone loss and ensuring better long-term outcomes.

Study of the Clinical Efficiency of an Interdisciplinary Approach to the Treatment of Orofacial Pain and Temporomandibular Joint Disorders in Patients with Complete or Partial Edentulism.