← Back to Search

Other

Carbohydrate Fluids for Postoperative Nausea and Vomiting (PONV Trial)

N/A
Waitlist Available
Led By Angeline Nguyen, DMD
Research Sponsored by Boston Medical Center
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be older than 18 years old
Must not have
Patient refusal
General Anesthesia using total IV anesthesia (TIVA)
Timeline
Screening 3 weeks
Treatment Varies
Follow Up 9 months
Awards & highlights
No Placebo-Only Group

Summary

This trial aims to test the effects of drinking a high-carbohydrate fluid (apple juice) before surgery on reducing nausea and vomiting after surgery. The study will follow a specific protocol during surgery to ensure

Who is the study for?
This trial is for patients undergoing oral and maxillofacial surgery at Boston Medical Center who can safely consume a carbohydrate drink before their operation. It's not specified who cannot join, but typically those with allergies to the study materials or conflicting medical conditions would be excluded.
What is being tested?
The study tests if drinking more than 50 grams of carbohydrates (like apple juice) before surgery can reduce nausea and vomiting after the operation. Patients will follow an Enhanced Recovery After Surgery protocol to limit other factors that could affect results.
What are the potential side effects?
Since the intervention involves consuming a carbohydrate drink, side effects are likely minimal but may include discomfort from drinking fluids pre-surgery or potential blood sugar changes in diabetic patients.

Eligibility Criteria

Exclusion Criteria

You may be eligible for the trial if you check “No” for criteria below:
Select...
I have chosen not to participate in certain treatments.
Select...
I will be put to sleep using drugs given through an IV for my surgery.
Select...
I have diabetes, an endocrine disorder, or an allergy to certain medications.

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~9 months
This trial's timeline: 3 weeks for screening, Varies for treatment, and 9 months for reporting.

Treatment Details

Study Objectives

Study objectives can provide a clearer picture of what you can expect from a treatment.
Primary study objectives
Intensity of post operative nausea and vomiting (PONV)
PONV based on the visual analog scale
Secondary study objectives
Frequency of emesis events
Length of hospital stay
Need for intravenous (IV) fluids
+3 more
Other study objectives
Patient Apfel Score

Awards & Highlights

No Placebo-Only Group
All patients enrolled in this study will receive some form of active treatment.

Trial Design

2Treatment groups
Experimental Treatment
Active Control
Group I: Preoperative carbohydrate drinkExperimental Treatment1 Intervention
Participants randomized into this group will receive a carbohydrate drink before surgery.
Group II: Preoperative fastingActive Control1 Intervention
Participants randomized into this group will be fasting/nothing by mouth (NPO) before surgery.

Find a Location

Who is running the clinical trial?

Boston Medical CenterLead Sponsor
401 Previous Clinical Trials
886,351 Total Patients Enrolled
Angeline Nguyen, DMDPrincipal InvestigatorBoston Medical Center, Oral and Maxillofacial Surgery
~21 spots leftby Feb 2025
Unbiased ResultsWe believe in providing patients with all the options.
Your Data Stays Your DataWe only share your information with the clinical trials you're trying to access.
Verified Trials OnlyAll of our trials are run by licensed doctors, researchers, and healthcare companies.
Back to top