Mapping and Biopsy Study for Kidney Stones
Trial Summary
What is the purpose of this trial?
Kidney stones are very common. They affect 3-5% of the population in the United States. Many people are hospitalized for the treatment of kidney stones and some may die. Better understanding of what causes kidney stones is useful in both the treatment and prevention of kidney stones. However, exactly what causes kidney stones is unknown. The most common type of kidney stones contains calcium, which sometimes is attached to a part of the kidney important in producing the final urine, called the papilla. The investigators have noticed that persons who form kidney stones seem to have more papilla with stones attached. They propose to study these areas of the papilla, called Randall's plaques (named after their discoverer), in patients undergoing surgery for kidney stones.
Do I have to stop taking my current medications for this trial?
The trial protocol does not specify whether you need to stop taking your current medications.
What data supports the idea that Mapping and Biopsy Study for Kidney Stones is an effective treatment?
The available research shows that renal biopsy, a key part of the Mapping and Biopsy Study for Kidney Stones, is highly valued for its role in diagnosing and managing kidney diseases. It is considered the best method for understanding kidney conditions, as it provides detailed information that other imaging techniques cannot. This makes it an essential tool for doctors to make informed decisions about patient care. While the studies focus on kidney disease in general, they highlight the importance and effectiveness of biopsy in improving patient outcomes.12345
What safety data exists for the kidney stone mapping and biopsy treatment?
The safety data for kidney biopsy, which is related to the treatment, indicates that it is a diagnostic tool with a low rate of complications. Studies have evaluated the safety of obtaining extra biopsy cores for biobanking and found that it does not significantly increase the risk of complications. Additionally, systematic reviews and registries have been established to track and analyze complications, primarily focusing on bleeding risks, to improve patient care and outcomes.26789
Is the treatment in the Mapping and Biopsy Study for Kidney Stones a promising treatment?
Yes, the treatment in the Mapping and Biopsy Study for Kidney Stones is promising because it uses a laparoscopic approach, which is less invasive than traditional open surgery. This method achieves the same goals with fewer complications, making it a valuable tool for diagnosing kidney issues.1011121314
Research Team
James Lingeman, MD
Principal Investigator
IU Health Physicians Urology
Eligibility Criteria
This trial is for people in good health who need surgery to remove kidney stones or treat other urologic conditions at Methodist Urology in Indianapolis, IN. Participants must be able to complete all study requirements and sign a consent form. Those with bleeding disorders, poor health, or unable to follow post-surgery instructions cannot join.Inclusion Criteria
Exclusion Criteria
Treatment Details
Interventions
- Videotape for Mapping of Renal Anatomy and Papillary Biopsy (Procedure)
Find a Clinic Near You
Who Is Running the Clinical Trial?
Indiana Kidney Stone Institute
Lead Sponsor
Indiana University School of Medicine
Collaborator
University of Chicago
Collaborator