Resistant Starch for Chronic Kidney Disease (ReSPECKD Trial)

Palo Alto (17 mi)

Overseen byDylan Mackay, PhD

Age: 18+

Sex: Any

Travel: May be covered

Time Reimbursement: Varies

Trial Phase: N/A

Waitlist Available

Sponsor: University of Manitoba

Stay on your current meds

Trial Summary

What is the purpose of this trial?This trial tests if taking Resistant Potato Starch (RPS) can help patients with Chronic Kidney Disease by improving their gut bacteria and reducing harmful blood toxins. A high resistant starch diet has shown to slow down CKD progression and reduce oxidative stress and inflammation in rats.

Eligibility Criteria

Adults over 18 with Chronic Kidney Disease (CKD) and an eGFR <15 mL/min/1.73m^2, who can read English and consent to study requirements. Women must use birth control if of child-bearing potential. Excludes those with uncontrolled diabetes (A1C > 10%), cognitive impairments, allergies to potatoes or corn, severe gastrointestinal conditions, severe anemia, recent antibiotic use, or on dialysis.

Treatment Details

The trial is testing whether resistant potato starch can reduce uremic toxins by changing gut bacteria in CKD patients compared to standard corn starch. Participants will add this to their usual CKD care regimen to see if it improves symptoms and delays the need for dialysis.

2Treatment groups

Experimental Treatment

Placebo Group

Group I: Resistant Potato StarchExperimental Treatment1 Intervention

15g RPS mixed with water will be consumed twice per day during intervention

Group II: Corn StarchPlacebo Group1 Intervention

15 g corn starch mixed with water will be consumed twice per day during intervention