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Behavioral Intervention

Cognitive Training for Serious Mental Illness

N/A
Waitlist Available
Led By Gregory Light, PhD
Research Sponsored by VA Office of Research and Development
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Ability to see with an acuity of 20/40 with both eyes tested together (corrected if applicable) by a standard printed Snellen eye chart reading card
Age between 18 and 75 years
Must not have
Inability to comprehend or provide informed consent
Timeline
Screening 3 weeks
Treatment Varies
Follow Up 22 weeks
Awards & highlights
No Placebo-Only Group

Summary

This trial aims to introduce a new therapy called Targeted Cognitive Training (TCT) to Veterans with serious mental illnesses (SMI) who are receiving care in VA Psychosocial Rehabilitation and Recovery Centers

Who is the study for?
This trial is for Veterans with serious mental illnesses like schizophrenia, bipolar disorder, psychosis, or PTSD who are receiving care in VA Psychosocial Rehabilitation and Recovery Centers. It's designed to help those struggling with cognitive impairments due to their conditions.
What is being tested?
The study tests Targeted Cognitive Training (TCT), a new therapy aimed at improving sensory information processing and overall brain function which may lead to better clinical outcomes and quality of life for Veterans with serious mental illnesses.
What are the potential side effects?
Since TCT is a form of cognitive therapy involving exercises or tasks rather than medication, it typically does not have physical side effects. However, participants might experience frustration or fatigue during the training.

Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below
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I can see clearly from 20 feet what should normally be seen at that distance.
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I am between 18 and 75 years old.

Exclusion Criteria

You may be eligible for the trial if you check “No” for criteria below:
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I am able to understand and give informed consent.

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~22 weeks
This trial's timeline: 3 weeks for screening, Varies for treatment, and 22 weeks for reporting.

Treatment Details

Study Objectives

Study objectives can provide a clearer picture of what you can expect from a treatment.
Primary study objectives
Clinical Symptoms - Positive and Negative Syndrome Scale (PANSS)
Cognition - Matrics Consensus Cognitive Battery (MCCB)
Function - Functional Capacity: UCSD Performance-Based Skills Assessment, Brief Version (UPSA-B)
+1 more

Awards & Highlights

No Placebo-Only Group
All patients enrolled in this study will receive some form of active treatment.

Trial Design

2Treatment groups
Active Control
Group I: TCT + TAUActive Control1 Intervention
Subjects will complete 30 hours of Targeted Cognitive Training (TCT) in addition to their Treatment as Usual (TAU)
Group II: TAUActive Control1 Intervention
Subjects will participate in their standard Treatment as Usual (TAU) PRRC program

Find a Location

Who is running the clinical trial?

VA Office of Research and DevelopmentLead Sponsor
1,664 Previous Clinical Trials
3,765,591 Total Patients Enrolled
7 Trials studying Psychosis
1,665 Patients Enrolled for Psychosis
University of California, San DiegoOTHER
1,187 Previous Clinical Trials
1,576,767 Total Patients Enrolled
3 Trials studying Psychosis
277 Patients Enrolled for Psychosis
Gregory Light, PhDPrincipal InvestigatorVA San Diego Healthcare System, San Diego, CA
~53 spots leftby Aug 2028