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Procedure
Initial Management of Patients Receiving a Single Shock (IMPRESS) (IMPRESS Trial)
N/A
Waitlist Available
Led By Sanjaya Gupta, MD
Research Sponsored by Sanjaya Gupta
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial Must have
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up 12 months
Awards & highlights
No Placebo-Only Group
Summary
This trial aims to find the best treatment for patients who have received a single shock from their heart device (ICD). It uses a special vest and a procedure to see if their heart can be made to beat too fast. If it can, doctors will decide whether medication or a corrective procedure is better. The goal is to reduce future shocks and hospital visits. The ICD has evolved to overcome the limitations of earlier devices and is now implanted similarly to cardiac pacemakers.
Eligible Conditions
- Ventricular Tachycardia
Timeline
Screening ~ 3 weeks3 visits
Treatment ~ Varies
Follow Up ~ 12 months
Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~12 months
Treatment Details
Study Objectives
Study objectives can provide a clearer picture of what you can expect from a treatment.Primary study objectives
ICD Shocks
Secondary study objectives
ATP Therapy as recorded by ICD
Hospitalizations
Initiation of antiarrythmic medication
+3 moreAwards & Highlights
No Placebo-Only Group
All patients enrolled in this study will receive some form of active treatment.
Trial Design
3Treatment groups
Experimental Treatment
Active Control
Group I: Ventricular Tachycardia AblationExperimental Treatment2 Interventions
Patients who have a positive NIPS study and are randomized to the ablation arm will undergo ventricular tachycardia ablation procedure guided by CardioInsight.
Group II: Negative NIPS/Non-interventionExperimental Treatment1 Intervention
Patients who had a negative NIPS study will not be assigned to a treatment group and will be followed according to standard of care.
Group III: Standard medical therapyActive Control2 Interventions
Patients who have a positive NIPS study and are randomized to the medical therapy arm will either be initiated on antiarrhythmic therapy or will have their antiarrhythmic therapy intensified. All medication therapy is considered usual standard therapy.
Find a Location
Who is running the clinical trial?
Sanjaya GuptaLead Sponsor
2 Previous Clinical Trials
534 Total Patients Enrolled
Saint Luke's Health SystemLead Sponsor
41 Previous Clinical Trials
12,916 Total Patients Enrolled
MedtronicIndustry Sponsor
619 Previous Clinical Trials
764,058 Total Patients Enrolled
Sanjaya Gupta, MDPrincipal Investigator - Saint Luke's Health System
Anderson County Hospital, Cardiovascular Consultants PC, Hedrick Medical Center, SLCC Inc., Saint Luke's Cushing Hospital, St. Luke's East Hospital, St. Luke's Northland Hospital-Barry Rd Campus, St. Luke's South Hosital, Wright Memorial Hospital
St Louis University School Of Medicine (Medical School)
University Of Mi Hosps (Residency)
3 Previous Clinical Trials
566 Total Patients Enrolled