Ventricular Tachycardia Ablation for Ventricular Tachycardia (IMPRESS Trial)

N/A

Waitlist Available

Led By Sanjaya Gupta, MD

Research Sponsored by Sanjaya Gupta

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

Be older than 18 years old

Timeline

Screening 3 weeks

Treatment Varies

Follow Up 12 months

Awards & highlights

No Placebo-Only Group

Summary

This trial aims to find the best treatment for patients who have received a single shock from their heart device (ICD). It uses a special vest and a procedure to see if their heart can be made to beat too fast. If it can, doctors will decide whether medication or a corrective procedure is better. The goal is to reduce future shocks and hospital visits. The ICD has evolved to overcome the limitations of earlier devices and is now implanted similarly to cardiac pacemakers.

Eligible Conditions

Ventricular Tachycardia

Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ 12 months

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~12 months

This trial's timeline: 3 weeks for screening, Varies for treatment, and 12 months for reporting.

Treatment Details

Study Objectives

Study objectives can provide a clearer picture of what you can expect from a treatment.

Primary study objectives

ICD Shocks

Secondary study objectives

ATP Therapy as recorded by ICD

Hospitalizations

Initiation of antiarrythmic medication

+3 more

Awards & Highlights

No Placebo-Only Group

All patients enrolled in this study will receive some form of active treatment.

Trial Design

3Treatment groups

Experimental Treatment

Active Control

Group I: Ventricular Tachycardia AblationExperimental Treatment2 Interventions

Patients who have a positive NIPS study and are randomized to the ablation arm will undergo ventricular tachycardia ablation procedure guided by CardioInsight.

Group II: Negative NIPS/Non-interventionExperimental Treatment1 Intervention

Patients who had a negative NIPS study will not be assigned to a treatment group and will be followed according to standard of care.

Group III: Standard medical therapyActive Control2 Interventions

Patients who have a positive NIPS study and are randomized to the medical therapy arm will either be initiated on antiarrhythmic therapy or will have their antiarrhythmic therapy intensified. All medication therapy is considered usual standard therapy.

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