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Neurostimulation

MRI Study of High Definition Transcranial Electrical Stimulation in Chronic Tinnitus (MRI HDtES-T) (MRI HDtES-T Trial)

N/A
Waitlist Available
Research Sponsored by Northwestern University
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up 1 week, 2 weeks, 1 month

Summary

This trial is testing a gentle brain stimulation technique called HDtES on adults who have chronic ringing in their ears. The treatment uses small electrodes to send a mild electrical current through the scalp, aiming to change brain activity and connections. Researchers will measure changes in brain function and tinnitus symptoms over time. High-definition transcranial direct current stimulation (HD-tDCS) has been explored in previous studies for its potential to modulate brain activity and improve auditory processing in tinnitus patients.

Eligible Conditions
  • Ringing in the Ears

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~1 week, 2 weeks, 1 month
This trial's timeline: 3 weeks for screening, Varies for treatment, and 1 week, 2 weeks, 1 month for reporting.

Treatment Details

Study Objectives

Study objectives can provide a clearer picture of what you can expect from a treatment.
Primary study objectives
Changes in brain functional connectivity.
Secondary study objectives
Changes in tinnitus symptoms

Side effects data

From 2021 Phase 2 & 3 trial • 160 Patients • NCT02483468
2%
skin irritation
2%
Car accident
100%
80%
60%
40%
20%
0%
Study treatment Arm
tDCS (Active)
tDCS (Sham)

Trial Design

2Treatment groups
Experimental Treatment
Placebo Group
Group I: ActiveExperimental Treatment1 Intervention
Group II: ShamPlacebo Group1 Intervention
Treatment
First Studied
Drug Approval Stage
How many patients have taken this drug
Transcranial Direct Current Stimulation
2014
Completed Phase 3
~1100

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Who is running the clinical trial?

Northwestern UniversityLead Sponsor
1,652 Previous Clinical Trials
961,495 Total Patients Enrolled
~5 spots leftby Dec 2025
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