Popular Trials
Hormone Therapy
Continuous Glucose Monitoring and Insulin for Ketosis-Prone Diabetes
This trial aims to measure how blood sugar levels change daily during treatment for a specific type of diabetes called ketosis-prone diabetes (KPDM). Researchers will use a mathematical model to explain how KPDM
Procedure
Metabolic Surgery for Type 2 Diabetes
This trial is testing whether or not a vertical sleeve gastrectomy, a type of weight loss surgery, can help improve Type 2 diabetes in youth by looking at changes in things like insulin resistance, glycemic control, beta-cell function, and cardiovascular health.
Behavioural Intervention
Aerobic Exercise for Type 2 Diabetes
This trial is designed to study how well exercise training works to improve cardiovascular function in people with type 2 diabetes, as well as the mechanisms underlying Endothelial Progenitor Cell (EPC) dysfunction in this population.
Popular Filters
Trials for T2D Patients
Angiotensin II Receptor Blocker, COX-2 Inhibitor, Biguanide
Valsartan + Celecoxib + Metformin for Type 2 Diabetes
This trial is evaluating the safety, tolerability and superiority of RK-01, a valsartan plus celecoxib dual add-on to metformin-HCL XR over metformin in newly diagnosed and obese adult type 2 diabetes patients with high blood pressure, arthritis and inadequate glycemic control with metformin monotherapy, diet and exercise. The objective is to assess the effect of RK-01 on hemoglobin A1c (HbA1c) levels, beta cell function and insulin resistance with co-administration of valsartan, celecoxib and metformin-HCl X
Trials for Diabetes Patients
NAD+ precursor
NAD Augmentation for Diabetic Kidney Disease
This trial is testing whether NMN, a compound that may improve cell function, can help older adults with type 2 diabetes and high urine protein levels. The goal is to see if NMN can reduce kidney damage by improving cell energy production. Participants will receive NMN to compare the effects.
Potassium Channel Opener
Diazoxide for Type 2 Diabetes
This trial is testing diazoxide, a drug that activates parts of the brain, on people with type 2 diabetes. The goal is to see if it can help reduce the amount of glucose produced by the liver. By doing so, it may help manage high blood sugar levels in these patients. Diazoxide has been shown to improve blood sugar levels, help with weight loss, and affect certain genes in animal studies.
Phase 3 Trials
Ertugliflozin for Pediatric Type 2 Diabetes
This trial will study whether ertugliflozin is safe and effective in children with Type 2 Diabetes who are already taking metformin and/or insulin. The goal is to see if ertugliflozin can help lower HbA1C levels more than placebo after 24 weeks.
GLP-1 Receptor Agonist
Oral Semaglutide for Type 2 Diabetes in Youth
This trial is testing a new diabetes medicine called semaglutide. It focuses on children and teenagers with type 2 diabetes to see if the new medicine is safe and effective. Semaglutide helps control blood sugar levels, which is crucial for managing diabetes. It has been shown to improve blood sugar control and promote weight loss in patients with type 2 diabetes.
Glucagon-like peptide-1 receptor agonist
Semaglutide for Type 2 Diabetes with Chronic Kidney Disease
This trial is testing if semaglutide can help fight chronic kidney disease in people with type 2 diabetes. Participants will be randomly assigned to receive either semaglutide or placebo, and will be monitored for a year through clinic visits and phone calls. Blood and urine samples will be taken, and participants will also have MRI scans.
Glucagon-like peptide-1 (GLP-1) receptor agonist
Tirzepatide for Pediatric Type 2 Diabetes
This trial is testing tirzepatide, a medication that helps control blood sugar levels, in children and teenagers with type 2 diabetes. These participants are already taking other diabetes medications like metformin or basal insulin. Tirzepatide works by helping the body use insulin more effectively and reducing sugar production in the liver. Tirzepatide is a new medication being tested for its effectiveness and safety in people with type 2 diabetes.
Trials With No Placebo
Monoclonal Antibodies
Aflibercept for Diabetic Macular Edema
This trial investigates the effects of different treatments on patients with diabetic macular edema (DME) who have undergone vitrectomy surgery. The study found that anti-VEGF therapy, particularly ran
Behavioural Intervention
Morning vs Evening Exercise for Prediabetes
"This trial aims to study how exercising at different times of the day affects metabolism, sleep, and other factors. Participants will go through screening visits, follow specific diets, complete exercise conditions in a random order
Behavioral Intervention
Small Steps for Big Changes Program for Prediabetes
This trial evaluates the effectiveness of the 'Small Steps for Big Changes' (SSBC) program, designed to help people with prediabetes improve their diet and exercise habits. The goal is to see if these changes can lower blood sugar levels, reduce weight, and decrease waist size over time. Participants receive personalized guidance and support from trainers at YMCA locations. The 'Small Steps for Big Changes' (SSBC) program emphasizes behavior change techniques and motivational interviewing to help adults at risk for type 2 diabetes.
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Frequently Asked Questions
Introduction to type 2 diabetes
What are the top hospitals conducting type 2 diabetes research?
In the ongoing battle against type 2 diabetes, several hospitals are leading the charge in conducting groundbreaking clinical trials. One such institution is the Novo Nordisk Investigational Site in Los Angeles, where researchers are currently engaged in six active trials focused on this prevalent condition. Although they have not yet completed any previous trials specifically for type 2 diabetes, their dedication to finding innovative treatments is evident. Similarly committed to advancing diabetes research is the Iowa Diabetes and Endocrinology Research Center located in West Des Moines. With five ongoing clinical trials dedicated to type 2 diabetes, this center has yet to complete any prior studies pertaining directly to this disease but stands as a beacon of hope for patients seeking novel treatment options.
Heading south to Dallas, we find another institution at the forefront of type 2 diabetes research: The Dallas Diabetes Research Center embarks on five active clinical trials aimed solely at tackling this chronic illness. While they may not have conducted any past studies relevant to type 2 diabetes thus far, their current endeavors demonstrate an unwavering commitment towards improving patient outcomes and quality of life.
Meanwhile, Novo Nordisk Investigational Site in San Antonio also joins forces with its Los Angeles counterpart by initiating five concurrent clinical trials that address various aspects of type 2 diabetes management. As with their previous counterparts discussed above, no prior specific investigations can be attributed solely toward combating Type- II-diabetes.On a similar note,Rainier Clinical Research Center located Renton places emphasis on fighting against Type-II-diabetes by focusing four ongoing trial projects while lacking previously recorded explicit undertakings
These hospitals stand as beacons of collaboration between medical professionals and brave individuals who volunteer for these trials; united by a common goal - changing lives through scientific advancements and breakthroughs against one of today's most pressing health concerns
Which are the best cities for type 2 diabetes clinical trials?
When it comes to type 2 diabetes clinical trials, several cities have emerged as leading centers for research and development. San Antonio, Texas, boasts 17 active trials investigating treatments like Cohort A: AMG 133 and HTD1801. Las Vegas, Nevada follows closely with 16 ongoing studies focused on Orforglipron and Empagliflozin. Additionally, Los Angeles, California contributes to the advancement of diabetes care through its 15 active trials exploring Semaglutide and Tirzepatide among others. These cities offer individuals with type 2 diabetes access to cutting-edge clinical trials that pave the way for potential breakthroughs in treatment options.
Which are the top treatments for type 2 diabetes being explored in clinical trials?
Clinical trials are actively investigating several promising treatments for type 2 diabetes. Standout contenders include:
- Semaglutide: A drug showing great potential, currently being explored in six ongoing clinical trials.
- Sotagliflozin: Another treatment gaining attention, with involvement in four active trials.
- Dapagliflozin: This medication is also under investigation and has appeared in three ongoing studies. With each trial, researchers strive to uncover new therapies that can effectively manage type 2 diabetes and improve the lives of patients worldwide.
What are the most recent clinical trials for type 2 diabetes?
Recent clinical trials offer new insights and potential treatments for individuals with type 2 diabetes. One notable study is investigating Orforglipron Dose 2, reaching Phase 3 to assess its effectiveness in managing the condition. Another trial focuses on receiving treatment specifically tailored for type 2 diabetes, aiming to improve patients' overall well-being. Additionally, an intriguing Phase 1 trial explores the use of Active THC as a potential therapeutic option. These ongoing studies reflect the scientific community's commitment to finding innovative solutions that could transform the lives of those living with type 2 diabetes into healthier and more manageable ones.
What type 2 diabetes clinical trials were recently completed?
Several clinical trials focusing on type 2 diabetes have recently concluded, bringing potential advancements in treatment for this prevalent metabolic disorder. These recent completions include a trial investigating the efficacy of an innovative medication sponsored by Johnson & Johnson. Additionally, Novo Nordisk completed a study evaluating a new insulin formulation specifically designed to address the needs of individuals with type 2 diabetes. These exciting developments highlight ongoing efforts to improve management options and enhance quality of life for those living with this chronic condition.