Bactrim Ds

Shigellosis, Nocardiosis, Brucellosis + 16 more
Treatment
17 FDA approvals
19 Active Studies for Bactrim Ds

What is Bactrim Ds

TrimethoprimThe Generic name of this drug
Treatment SummarySulfamethoxazole is an antibiotic used to treat bacterial infections. It works by blocking the bacteria's ability to create folic acid, an important component for growth. When used with trimethoprim, it is effective in treating urinary tract infections, respiratory infections, and gastrointestinal infections.
Septra DSis the brand name
image of different drug pills on a surface
Bactrim Ds Overview & Background
Brand Name
Generic Name
First FDA Approval
How many FDA approvals?
Septra DS
Trimethoprim
1973
343

Approved as Treatment by the FDA

Trimethoprim, also called Septra DS, is approved by the FDA for 17 uses including Pneumonia, Pneumocystis and Nocardiosis .
Pneumonia, Pneumocystis
Used to treat Pneumocystis Jirovecii Pneumonia in combination with Sulfamethoxazole
Nocardiosis
Used to treat Nocardiosis in combination with Sulfamethoxazole
susceptible Enteritis infectious caused by Shigella sonnei
Used to treat susceptible Enteritis infectious caused by Shigella sonnei in combination with Sulfamethoxazole
Otitis Media
Used to treat Acute Otitis Media caused by susceptible bacteria in combination with Sulfamethoxazole
Brucellosis
Used to treat Brucellosis in combination with Rifampicin
Electrolyte replacement
Used to treat Electrolyte replacement in combination with Sulfamethoxazole
Fluid replacement therapy
Used to treat Fluid replacement therapy in combination with Sulfamethoxazole
Cholera
Used to treat susceptible Cholera in combination with Sulfamethoxazole
Genus Pneumocystis
Used to treat risk of Pneumocystis jiroveci pneumonia (PCP) in combination with Sulfamethoxazole
Urinary tract infection
Used to treat Urinary Tract Infection caused by susceptible bacteria in combination with Sulfamethoxazole
Pneumocystis Jirovecii Pneumonia
Used to treat Pneumocystis Jirovecii Pneumonia in combination with Sulfamethoxazole
Shigellosis
Used to treat Dysentery, Bacillary in combination with Sulfamethoxazole
Bronchitis
Used to treat Acute Exacerbation of Chronic Bronchitis (AECB) caused by susceptible bacteria in combination with Sulfamethoxazole
Diarrhea
Used to treat susceptible Travelers' Diarrhea caused by Enterotoxigenic E. Coli (ETEC) Infection in combination with Sulfamethoxazole
susceptible Enteritis infectious caused by Shigella flexneri
Used to treat susceptible Enteritis infectious caused by Shigella flexneri in combination with Sulfamethoxazole
Brucellosis
Used to treat Brucellosis in combination with Rifampicin
Immunocompromised
Used to treat Immunocompromised in combination with Sulfamethoxazole

Effectiveness

How Bactrim Ds Affects PatientsSulfamethoxazole is an antibiotic used to fight bacteria. It is most often used in combination with another antibiotic called trimethoprim, as this prevents bacteria from developing a resistance to the treatment. However, sulfamethoxazole can cause allergic reactions, ranging from mild rashes to severe reactions like Stevens-Johnson syndrome or toxic epidermal necrolysis. It can also cause folate deficiency in some people, and can lead to hemolysis (breakdown of red blood cells) in people with glucose-6-phosphate dehydrogenase deficiency.
How Bactrim Ds works in the bodySulfamethoxazole is a medication that works to stop bacteria from reproducing. It does this by blocking the enzyme responsible for converting a compound found in bacteria into folic acid, which is essential for bacterial growth. When the enzyme is blocked, the bacteria can't produce the folic acid needed for them to reproduce, resulting in a slowdown of their growth.

When to interrupt dosage

The prescribed dosage of Bactrim Ds is contingent upon the determined issue, including Urinary tract infection, Pneumocystis Jirovecii Pneumonia and Fluid replacement therapy. The amount of dosage is contingent upon the administration process outlined in the table hereunder.
Condition
Dosage
Administration
Brucellosis
, 1.0 mg/mL, 160.0 mg, 80.0 mg, 40.0 mg/mL, 50.0 mg/mL, 100.0 mg, 0.16 mg, 1.6 mg, 20.0 mg, 200.0 mg, 90.0 mg, 16.0 mg/mL, 300.0 mg, 40.0 mg, 8.0 mg/mL, 9.0 mg/mL
, Ophthalmic, Solution / drops - Ophthalmic, Oral, Tablet, Tablet - Oral, Suspension, Suspension - Oral, Solution, Solution - Oral, Solution - Ophthalmic, Intravenous, Liquid, Liquid - Intravenous, Injection, solution, concentrate, Injection, solution, concentrate - Intravenous, Solution - Intravenous, Injection, Injection - Intravenous, Solution / drops, Liquid - Ophthalmic
Nocardiosis
, 1.0 mg/mL, 160.0 mg, 80.0 mg, 40.0 mg/mL, 50.0 mg/mL, 100.0 mg, 0.16 mg, 1.6 mg, 20.0 mg, 200.0 mg, 90.0 mg, 16.0 mg/mL, 300.0 mg, 40.0 mg, 8.0 mg/mL, 9.0 mg/mL
, Ophthalmic, Solution / drops - Ophthalmic, Oral, Tablet, Tablet - Oral, Suspension, Suspension - Oral, Solution, Solution - Oral, Solution - Ophthalmic, Intravenous, Liquid, Liquid - Intravenous, Injection, solution, concentrate, Injection, solution, concentrate - Intravenous, Solution - Intravenous, Injection, Injection - Intravenous, Solution / drops, Liquid - Ophthalmic
Immunocompromised
, 1.0 mg/mL, 160.0 mg, 80.0 mg, 40.0 mg/mL, 50.0 mg/mL, 100.0 mg, 0.16 mg, 1.6 mg, 20.0 mg, 200.0 mg, 90.0 mg, 16.0 mg/mL, 300.0 mg, 40.0 mg, 8.0 mg/mL, 9.0 mg/mL
, Ophthalmic, Solution / drops - Ophthalmic, Oral, Tablet, Tablet - Oral, Suspension, Suspension - Oral, Solution, Solution - Oral, Solution - Ophthalmic, Intravenous, Liquid, Liquid - Intravenous, Injection, solution, concentrate, Injection, solution, concentrate - Intravenous, Solution - Intravenous, Injection, Injection - Intravenous, Solution / drops, Liquid - Ophthalmic
Pneumonia, Pneumocystis
, 1.0 mg/mL, 160.0 mg, 80.0 mg, 40.0 mg/mL, 50.0 mg/mL, 100.0 mg, 0.16 mg, 1.6 mg, 20.0 mg, 200.0 mg, 90.0 mg, 16.0 mg/mL, 300.0 mg, 40.0 mg, 8.0 mg/mL, 9.0 mg/mL
, Ophthalmic, Solution / drops - Ophthalmic, Oral, Tablet, Tablet - Oral, Suspension, Suspension - Oral, Solution, Solution - Oral, Solution - Ophthalmic, Intravenous, Liquid, Liquid - Intravenous, Injection, solution, concentrate, Injection, solution, concentrate - Intravenous, Solution - Intravenous, Injection, Injection - Intravenous, Solution / drops, Liquid - Ophthalmic
Urinary tract infection
, 1.0 mg/mL, 160.0 mg, 80.0 mg, 40.0 mg/mL, 50.0 mg/mL, 100.0 mg, 0.16 mg, 1.6 mg, 20.0 mg, 200.0 mg, 90.0 mg, 16.0 mg/mL, 300.0 mg, 40.0 mg, 8.0 mg/mL, 9.0 mg/mL
, Ophthalmic, Solution / drops - Ophthalmic, Oral, Tablet, Tablet - Oral, Suspension, Suspension - Oral, Solution, Solution - Oral, Solution - Ophthalmic, Intravenous, Liquid, Liquid - Intravenous, Injection, solution, concentrate, Injection, solution, concentrate - Intravenous, Solution - Intravenous, Injection, Injection - Intravenous, Solution / drops, Liquid - Ophthalmic
Urinary tract infection
, 1.0 mg/mL, 160.0 mg, 80.0 mg, 40.0 mg/mL, 50.0 mg/mL, 100.0 mg, 0.16 mg, 1.6 mg, 20.0 mg, 200.0 mg, 90.0 mg, 16.0 mg/mL, 300.0 mg, 40.0 mg, 8.0 mg/mL, 9.0 mg/mL
, Ophthalmic, Solution / drops - Ophthalmic, Oral, Tablet, Tablet - Oral, Suspension, Suspension - Oral, Solution, Solution - Oral, Solution - Ophthalmic, Intravenous, Liquid, Liquid - Intravenous, Injection, solution, concentrate, Injection, solution, concentrate - Intravenous, Solution - Intravenous, Injection, Injection - Intravenous, Solution / drops, Liquid - Ophthalmic
Conjunctivitis, Bacterial
, 1.0 mg/mL, 160.0 mg, 80.0 mg, 40.0 mg/mL, 50.0 mg/mL, 100.0 mg, 0.16 mg, 1.6 mg, 20.0 mg, 200.0 mg, 90.0 mg, 16.0 mg/mL, 300.0 mg, 40.0 mg, 8.0 mg/mL, 9.0 mg/mL
, Ophthalmic, Solution / drops - Ophthalmic, Oral, Tablet, Tablet - Oral, Suspension, Suspension - Oral, Solution, Solution - Oral, Solution - Ophthalmic, Intravenous, Liquid, Liquid - Intravenous, Injection, solution, concentrate, Injection, solution, concentrate - Intravenous, Solution - Intravenous, Injection, Injection - Intravenous, Solution / drops, Liquid - Ophthalmic
bacterial blepharitis caused by susceptible bacteria
, 1.0 mg/mL, 160.0 mg, 80.0 mg, 40.0 mg/mL, 50.0 mg/mL, 100.0 mg, 0.16 mg, 1.6 mg, 20.0 mg, 200.0 mg, 90.0 mg, 16.0 mg/mL, 300.0 mg, 40.0 mg, 8.0 mg/mL, 9.0 mg/mL
, Ophthalmic, Solution / drops - Ophthalmic, Oral, Tablet, Tablet - Oral, Suspension, Suspension - Oral, Solution, Solution - Oral, Solution - Ophthalmic, Intravenous, Liquid, Liquid - Intravenous, Injection, solution, concentrate, Injection, solution, concentrate - Intravenous, Solution - Intravenous, Injection, Injection - Intravenous, Solution / drops, Liquid - Ophthalmic
Diarrhea
, 1.0 mg/mL, 160.0 mg, 80.0 mg, 40.0 mg/mL, 50.0 mg/mL, 100.0 mg, 0.16 mg, 1.6 mg, 20.0 mg, 200.0 mg, 90.0 mg, 16.0 mg/mL, 300.0 mg, 40.0 mg, 8.0 mg/mL, 9.0 mg/mL
, Ophthalmic, Solution / drops - Ophthalmic, Oral, Tablet, Tablet - Oral, Suspension, Suspension - Oral, Solution, Solution - Oral, Solution - Ophthalmic, Intravenous, Liquid, Liquid - Intravenous, Injection, solution, concentrate, Injection, solution, concentrate - Intravenous, Solution - Intravenous, Injection, Injection - Intravenous, Solution / drops, Liquid - Ophthalmic
Shigellosis
, 1.0 mg/mL, 160.0 mg, 80.0 mg, 40.0 mg/mL, 50.0 mg/mL, 100.0 mg, 0.16 mg, 1.6 mg, 20.0 mg, 200.0 mg, 90.0 mg, 16.0 mg/mL, 300.0 mg, 40.0 mg, 8.0 mg/mL, 9.0 mg/mL
, Ophthalmic, Solution / drops - Ophthalmic, Oral, Tablet, Tablet - Oral, Suspension, Suspension - Oral, Solution, Solution - Oral, Solution - Ophthalmic, Intravenous, Liquid, Liquid - Intravenous, Injection, solution, concentrate, Injection, solution, concentrate - Intravenous, Solution - Intravenous, Injection, Injection - Intravenous, Solution / drops, Liquid - Ophthalmic
Electrolyte replacement
, 1.0 mg/mL, 160.0 mg, 80.0 mg, 40.0 mg/mL, 50.0 mg/mL, 100.0 mg, 0.16 mg, 1.6 mg, 20.0 mg, 200.0 mg, 90.0 mg, 16.0 mg/mL, 300.0 mg, 40.0 mg, 8.0 mg/mL, 9.0 mg/mL
, Ophthalmic, Solution / drops - Ophthalmic, Oral, Tablet, Tablet - Oral, Suspension, Suspension - Oral, Solution, Solution - Oral, Solution - Ophthalmic, Intravenous, Liquid, Liquid - Intravenous, Injection, solution, concentrate, Injection, solution, concentrate - Intravenous, Solution - Intravenous, Injection, Injection - Intravenous, Solution / drops, Liquid - Ophthalmic
Fluid replacement therapy
, 1.0 mg/mL, 160.0 mg, 80.0 mg, 40.0 mg/mL, 50.0 mg/mL, 100.0 mg, 0.16 mg, 1.6 mg, 20.0 mg, 200.0 mg, 90.0 mg, 16.0 mg/mL, 300.0 mg, 40.0 mg, 8.0 mg/mL, 9.0 mg/mL
, Ophthalmic, Solution / drops - Ophthalmic, Oral, Tablet, Tablet - Oral, Suspension, Suspension - Oral, Solution, Solution - Oral, Solution - Ophthalmic, Intravenous, Liquid, Liquid - Intravenous, Injection, solution, concentrate, Injection, solution, concentrate - Intravenous, Solution - Intravenous, Injection, Injection - Intravenous, Solution / drops, Liquid - Ophthalmic
Genus Pneumocystis
, 1.0 mg/mL, 160.0 mg, 80.0 mg, 40.0 mg/mL, 50.0 mg/mL, 100.0 mg, 0.16 mg, 1.6 mg, 20.0 mg, 200.0 mg, 90.0 mg, 16.0 mg/mL, 300.0 mg, 40.0 mg, 8.0 mg/mL, 9.0 mg/mL
, Ophthalmic, Solution / drops - Ophthalmic, Oral, Tablet, Tablet - Oral, Suspension, Suspension - Oral, Solution, Solution - Oral, Solution - Ophthalmic, Intravenous, Liquid, Liquid - Intravenous, Injection, solution, concentrate, Injection, solution, concentrate - Intravenous, Solution - Intravenous, Injection, Injection - Intravenous, Solution / drops, Liquid - Ophthalmic
Bacterial conjunctivitis
, 1.0 mg/mL, 160.0 mg, 80.0 mg, 40.0 mg/mL, 50.0 mg/mL, 100.0 mg, 0.16 mg, 1.6 mg, 20.0 mg, 200.0 mg, 90.0 mg, 16.0 mg/mL, 300.0 mg, 40.0 mg, 8.0 mg/mL, 9.0 mg/mL
, Ophthalmic, Solution / drops - Ophthalmic, Oral, Tablet, Tablet - Oral, Suspension, Suspension - Oral, Solution, Solution - Oral, Solution - Ophthalmic, Intravenous, Liquid, Liquid - Intravenous, Injection, solution, concentrate, Injection, solution, concentrate - Intravenous, Solution - Intravenous, Injection, Injection - Intravenous, Solution / drops, Liquid - Ophthalmic
Bronchitis
, 1.0 mg/mL, 160.0 mg, 80.0 mg, 40.0 mg/mL, 50.0 mg/mL, 100.0 mg, 0.16 mg, 1.6 mg, 20.0 mg, 200.0 mg, 90.0 mg, 16.0 mg/mL, 300.0 mg, 40.0 mg, 8.0 mg/mL, 9.0 mg/mL
, Ophthalmic, Solution / drops - Ophthalmic, Oral, Tablet, Tablet - Oral, Suspension, Suspension - Oral, Solution, Solution - Oral, Solution - Ophthalmic, Intravenous, Liquid, Liquid - Intravenous, Injection, solution, concentrate, Injection, solution, concentrate - Intravenous, Solution - Intravenous, Injection, Injection - Intravenous, Solution / drops, Liquid - Ophthalmic
susceptible Enteritis infectious caused by Shigella flexneri
, 1.0 mg/mL, 160.0 mg, 80.0 mg, 40.0 mg/mL, 50.0 mg/mL, 100.0 mg, 0.16 mg, 1.6 mg, 20.0 mg, 200.0 mg, 90.0 mg, 16.0 mg/mL, 300.0 mg, 40.0 mg, 8.0 mg/mL, 9.0 mg/mL
, Ophthalmic, Solution / drops - Ophthalmic, Oral, Tablet, Tablet - Oral, Suspension, Suspension - Oral, Solution, Solution - Oral, Solution - Ophthalmic, Intravenous, Liquid, Liquid - Intravenous, Injection, solution, concentrate, Injection, solution, concentrate - Intravenous, Solution - Intravenous, Injection, Injection - Intravenous, Solution / drops, Liquid - Ophthalmic
susceptible Enteritis infectious caused by Shigella sonnei
, 1.0 mg/mL, 160.0 mg, 80.0 mg, 40.0 mg/mL, 50.0 mg/mL, 100.0 mg, 0.16 mg, 1.6 mg, 20.0 mg, 200.0 mg, 90.0 mg, 16.0 mg/mL, 300.0 mg, 40.0 mg, 8.0 mg/mL, 9.0 mg/mL
, Ophthalmic, Solution / drops - Ophthalmic, Oral, Tablet, Tablet - Oral, Suspension, Suspension - Oral, Solution, Solution - Oral, Solution - Ophthalmic, Intravenous, Liquid, Liquid - Intravenous, Injection, solution, concentrate, Injection, solution, concentrate - Intravenous, Solution - Intravenous, Injection, Injection - Intravenous, Solution / drops, Liquid - Ophthalmic
Otitis Media
, 1.0 mg/mL, 160.0 mg, 80.0 mg, 40.0 mg/mL, 50.0 mg/mL, 100.0 mg, 0.16 mg, 1.6 mg, 20.0 mg, 200.0 mg, 90.0 mg, 16.0 mg/mL, 300.0 mg, 40.0 mg, 8.0 mg/mL, 9.0 mg/mL
, Ophthalmic, Solution / drops - Ophthalmic, Oral, Tablet, Tablet - Oral, Suspension, Suspension - Oral, Solution, Solution - Oral, Solution - Ophthalmic, Intravenous, Liquid, Liquid - Intravenous, Injection, solution, concentrate, Injection, solution, concentrate - Intravenous, Solution - Intravenous, Injection, Injection - Intravenous, Solution / drops, Liquid - Ophthalmic
Cholera
, 1.0 mg/mL, 160.0 mg, 80.0 mg, 40.0 mg/mL, 50.0 mg/mL, 100.0 mg, 0.16 mg, 1.6 mg, 20.0 mg, 200.0 mg, 90.0 mg, 16.0 mg/mL, 300.0 mg, 40.0 mg, 8.0 mg/mL, 9.0 mg/mL
, Ophthalmic, Solution / drops - Ophthalmic, Oral, Tablet, Tablet - Oral, Suspension, Suspension - Oral, Solution, Solution - Oral, Solution - Ophthalmic, Intravenous, Liquid, Liquid - Intravenous, Injection, solution, concentrate, Injection, solution, concentrate - Intravenous, Solution - Intravenous, Injection, Injection - Intravenous, Solution / drops, Liquid - Ophthalmic

Warnings

Bactrim Ds has seven contraindications. Under no circumstances should it be utilized alongside the conditions provided in the following table.Bactrim Ds Contraindications
Condition
Risk Level
Notes
Severe Hypersensitivity Reactions
Do Not Combine
Trimethoprim may interact with Pulse Frequency
Purpura, Thrombocytopenic, Idiopathic
Do Not Combine
hepatic damage
Do Not Combine
Megaloblastic anemia caused by Folate deficiency
Do Not Combine
unable to monitor renal function
Do Not Combine
Disease
Do Not Combine
Pulse Frequency
Do Not Combine
Severe Hypersensitivity Reactions
Do Not Combine
Trimethoprim may interact with Pulse Frequency
There are 20 known major drug interactions with Bactrim Ds.
Common Bactrim Ds Drug Interactions
Drug Name
Risk Level
Description
Abemaciclib
Major
The excretion of Abemaciclib can be decreased when combined with Trimethoprim.
Brigatinib
Major
The metabolism of Brigatinib can be decreased when combined with Trimethoprim.
Cabazitaxel
Major
The metabolism of Cabazitaxel can be decreased when combined with Trimethoprim.
Cisplatin
Major
The serum concentration of Cisplatin can be increased when it is combined with Trimethoprim.
Clofarabine
Major
The serum concentration of Clofarabine can be increased when it is combined with Trimethoprim.
Bactrim Ds Toxicity & Overdose RiskThe toxic dose of sulfamethoxazole in mice and rats is 2300mg/kg and 6200mg/kg respectively. Symptoms of overdose include loss of appetite, stomach pain, nausea, vomiting, dizziness, headache, drowsiness, and loss of consciousness. Other less common symptoms may include fever, blood in the urine, and formation of crystals in the urine. Later on, the patient may experience issues with their blood count and develop jaundice. Treatment should address the symptoms and may include cleaning the stomach or inducing vomiting. Lab tests should also be conducted to check for any issues with the blood or electrolytes
image of a doctor in a lab doing drug, clinical research

Bactrim Ds Novel Uses: Which Conditions Have a Clinical Trial Featuring Bactrim Ds?

8 active clinical trials are being conducted to explore the use of Bactrim Ds in Immunocompromised patients, Fluid replacement therapy and the treatment of susceptible Enteritis infections caused by Shigella sonnei.
Condition
Clinical Trials
Trial Phases
Urinary tract infection
0 Actively Recruiting
Bacterial conjunctivitis
0 Actively Recruiting
Bronchitis
0 Actively Recruiting
Nocardiosis
0 Actively Recruiting
Shigellosis
0 Actively Recruiting
Brucellosis
0 Actively Recruiting
bacterial blepharitis caused by susceptible bacteria
0 Actively Recruiting
Immunocompromised
3 Actively Recruiting
Not Applicable, Phase 1
Otitis Media
0 Actively Recruiting
Genus Pneumocystis
0 Actively Recruiting
Conjunctivitis, Bacterial
0 Actively Recruiting
Fluid replacement therapy
0 Actively Recruiting
Cholera
0 Actively Recruiting
Urinary tract infection
0 Actively Recruiting
susceptible Enteritis infectious caused by Shigella sonnei
0 Actively Recruiting
Pneumonia, Pneumocystis
1 Actively Recruiting
Phase 3
susceptible Enteritis infectious caused by Shigella flexneri
0 Actively Recruiting
Electrolyte replacement
0 Actively Recruiting
Diarrhea
14 Actively Recruiting
Phase 1, Phase 2, Not Applicable, Early Phase 1

Bactrim Ds Reviews: What are patients saying about Bactrim Ds?

5Patient Review
9/5/2021
Bactrim Ds for Urinary Tract Infection Prevention
I'm a teacher and got a UTI from not being able to use the restroom during the day. I'm 51 years old and had no problems taking this medication. Our bodies can react differently to medications, so I think it's important to keep that in mind when reading reviews like this. The infection was really bad (there was blood in my urine), so I received an antibiotic shot first, and then this oral antibiotic. In just three days, I felt almost back to normal.
5Patient Review
9/23/2022
Bactrim Ds for infection
I'm using this medication to treat cellulitis on my arm and so far I haven't noticed any negative side effects.
5Patient Review
4/3/2020
Bactrim Ds for Skin Infection
This cleared up the infection in my hand quickly and effectively.
4Patient Review
8/22/2019
Bactrim Ds for Urinary Tract Infection due to E. Coli Bacteria
Bactrim DS is a great drug. I have allergies to many antibiotics, but this one was gentle enough for me. The worst side effects I felt were tiredness and a headache, but both went away after the first few days. This antibiotic cleared my UTI infection after just two days. It works quickly and is very potent. I would recommend it to anyone who is sensitive to antibiotics like me. You can be put on a 5 day regimen and be cured with this antibiotic.
4Patient Review
9/18/2022
Bactrim Ds for Skin Infection
Bactrim was a very effective antibiotic for me, and I experienced few negative side effects. The only issue I had was that the pills were extremely large.
2.7Patient Review
8/26/2020
Bactrim Ds for infection
I'm not a fan of this medication. It's 1:30 in the morning and my jaw is killing me. I feels like it's stuck shut, and my arms are very sensitive. I feel weak and dizzy, and this feeling has lasted for days.
2Patient Review
11/12/2019
Bactrim Ds for Pneumonia caused by Bacteria
I had an allergic reaction to this drug that was very severe. I almost had to go to the emergency room because of it. Make sure you tell your doctor about any side effects you experience.
1.7Patient Review
10/1/2022
Bactrim Ds for Bacterial Urinary Tract Infection
Do your best to steer clear of this antibiotic. It caused me immense nausea and diarrhea within the first week, to the point where I had to take Gravol just to make it through the day. Additionally, it made me feel exhausted and my heart rate was all over the place.
1.7Patient Review
8/20/2020
Bactrim Ds for infection
I experienced a lot of the potential side effects while taking this medication and it was honestly pretty scary.
1Patient Review
2/2/2021
Bactrim Ds for Infection of Urinary Tract due to Enterobacter Cloacae
This drug is dangerous and webmd needs to do a better job of really Listing and checking the facts. Muscle weakness Lethargic overtired unable to get up and move loss of appetite and nausea. This Was BANNED in the UK and clinical studies show prolonged use compromises your immune system and the older you are the higher mortality rate when using! Update the true facts webmd or are you paid for big big pharma. The research is out there people this drug should be removed from usage.
1Patient Review
10/27/2022
Bactrim Ds for Skin Infection
BEWARE! This can burn the scrap out of your skin. Anyone allergic to sulfur beware! And, if you are not sure do NOT use this product. AVOID THIS PRODUCT !
1Patient Review
8/11/2022
Bactrim Ds for Urinary Tract Infection Prevention
Unfortunately, this medication caused me to shake uncontrollably all over my body. I won't be taking it again.
image of drug pills surrounding a glass of water symbolizing drug consumption

Patient Q&A Section about bactrim ds

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

What is the side effects of Bactrim DS?

", or any other sign that your body is not tolerating campath

If you experience any of the following side effects, call your doctor immediately: severe stomach pain, watery or bloody diarrhea (even if it occurs months after your last dose), a skin rash (even if it is mild), yellowing of your skin or eyes, a seizure, new or unusual joint pain, increased or decreased urination, swelling, bruising, or irritation around the IV needle, or any other sign that your body is not tolerating campath."

Answered by AI

What is bactrim ds used to treat?

"This medication is a combination of two antibiotics, sulfamethoxazole and trimethoprim. It can be used to treat a number of bacterial infections, such as those in the middle ear, respiratory system and intestine, as well as preventing and treating pneumocystis pneumonia."

Answered by AI

What is the difference between Bactrim and Bactrim DS?

"Bactrim is available in two tablet strengths: 400 mg sulfamethoxazole and 80 mg trimethoprim, and the "DS" form, which is double strength (800 mg sulfamethoxazole and 160 mg trimethoprim). Patients should follow their doctor's instructions and take all of the Bactrim prescribed."

Answered by AI

Is Bactrim DS a strong antibiotic?

"Bactrim is a powerful combination antibiotic, but it may not be appropriate for people with kidney or liver disease, or who are deficient in folate. The elderly are at a higher risk of experiencing side effects."

Answered by AI

Clinical Trials for Bactrim Ds

Image of University of Maryland, School of Medicine, Center for Vaccine Development and Global Health in Baltimore, United States.

Vaccine for E. coli Infections

18 - 49
All Sexes
Baltimore, MD
The study is designed to evaluate the safety, immunogenicity, and efficacy of the intramuscular administration of a CS6 based vaccine (CssBA) against ETEC co-administered with double mutant labile toxin (dmLT) in preventing moderate-severe diarrhea (MSD) following challenge with ETEC strain B7A in healthy adults. Approximately 72 adult participants, divided into 4 cohorts of 18, will be randomized 1:1 to receive vaccine (45 micrograms CssBA with 0.5 micrograms dmLT) or placebo (normal saline) on an outpatient basis. All participants will receive 3 intramuscular (IM) doses of vaccine or placebo at 3-week intervals (days 1, 22 and 43). Following vaccination, participants will be followed as outpatients for safety using a memory aid from the time of each vaccination through 7 days post each vaccination. Approximately 28 days (plus or minus 1 day) after receipt of the 3rd dose of study agent, participants meeting challenge criteria will be admitted to an inpatient unit and be administered an oral dose of 1 x 10\^10 cfu (colony-forming unit) of ETEC strain B7A. Five days after challenge, participants will be treated with ciprofloxacin, except in cases of known allergy or intolerance. Participants will be discharged from the inpatient unit when they have completed their 3-day antibiotic course and are able to care for themselves. After discharge from the inpatient unit, participants will return for clinic visits and have a phone visit to provide any updates on medication, medical history and AE/SAEs. The primary objectives are: 1) Estimate CssBA+dmLT efficacy in preventing moderate-severe diarrhea (MSD) following challenge with ETEC strain B7A in healthy adults. 2) Evaluate the safety of intramuscular injection of CssBA+dmLT.
Phase 2
Recruiting
University of Maryland, School of Medicine, Center for Vaccine Development and Global Health (+1 Sites)
Have you considered Bactrim Ds clinical trials? We made a collection of clinical trials featuring Bactrim Ds, we think they might fit your search criteria.Go to Trials
Have you considered Bactrim Ds clinical trials? We made a collection of clinical trials featuring Bactrim Ds, we think they might fit your search criteria.Go to Trials
Image of McGill University Health Centre (Royal Victoria Hospital and Montreal General Hospital) in Montreal, Canada.

Low-Dose Trimethoprim-Sulfamethoxazole for Pneumocystis Pneumonia

18 - 100
All Sexes
Montreal, Canada
Pneumocystis jirovecii pneumonia (PJP) is an opportunistic fungal infection of immunocompromised hosts which causes in significant morbidity and mortality. The current standard of care, trimethoprim-sulfamethoxazole (TMP-SMX) at a dose of 15-20 mg/kg/day of TMP, is associated with serious adverse events, including hypersensitivity reactions, drug-induced liver injury, cytopenia, and renal failure occurring among 20-60% of patients. The frequency of adverse events increases in a dose dependent manner and commonly limits the use of TMP-SMX. Reduced treatment doses of TMP-SMX for PJP reduced ADEs without mortality differences in a recent meta-analysis of observational studies. We therefore propose a Phase III randomized, placebo-controlled trial to directly compare the efficacy and safety of low dose (10 mg/kg/day of TMP) compared to the standard-of-care (15 mg/kg/day) among patients with PJP for the primary outcome of death, new mechanical ventilation, and change of treatment.
Phase 3
Waitlist Available
McGill University Health Centre (Royal Victoria Hospital and Montreal General Hospital)Emily G McDonald, MD MSc
Image of Temple University in Philadelphia, United States.

UV Water Treatment for Gastroenteritis in Children

6 - 59
All Sexes
Philadelphia, PA
Approximately 40 million people in the US are served by private, and frequently untreated, wells. Our best estimate is that 1.3 million cases of gastrointestinal illnesses (GI) per year are attributed to consuming water from untreated private wells in the US, but in reality, there are no robust epidemiological data that can be used to estimate cases of GI attributable to these sources. We propose the first randomized controlled trial (RCT) to estimate the burden of GI associated with private well water. We will test if household treatment of private well water by ultraviolet light (UV) vs. sham (inactive UV device) decreases the incidence of GI in children under 5. We will also examine the presence of viral, bacterial, and protozoan pathogens in stool and well water from participants. These data will fill a knowledge gap on sporadic GI associated with federally-unregulated private water supplies in the US.
Recruiting
Paid Trial
Temple UniversityHeather M Murphy, PhD
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