Loestrin Fe 1.5/30

Endometriosis, Low Testosterone, Osteoporosis + 16 more
Treatment
20 Active Studies for Loestrin Fe 1.5/30

What is Loestrin Fe 1.5/30

NorethisteroneThe Generic name of this drug
Treatment SummaryNorethisterone, also known as norethindrone, is a synthetic hormone that is used to mimic the effects of progesterone. It is more powerful than naturally occurring progesterone and has been used for contraception, hormone replacement therapy, and irregular menstruation and endometriosis since its introduction in 1951. Norethisterone was approved for oral contraceptive use in 1962.
Neconis the brand name
image of different drug pills on a surface
Loestrin Fe 1.5/30 Overview & Background
Brand Name
Generic Name
First FDA Approval
How many FDA approvals?
Necon
Norethisterone
1967
347

Effectiveness

How Loestrin Fe 1.5/30 Affects PatientsNorethisterone is a type of drug used as birth control or to treat hormone-related conditions like menopause symptoms and endometriosis. It is a synthetic version of the hormone progesterone, meaning it is more powerful than the naturally occurring progesterone. Norethisterone works mainly by affecting the pelvic area and hormones that control ovulation. Using combined oral contraceptives (birth control pills) containing norethisterone may slightly increase the risk of developing breast cancer, so patients should be aware of this risk and do regular breast self-exams.
How Loestrin Fe 1.5/30 works in the bodyNorethisterone works on many parts of the body; in the reproductive tract, breast, pituitary, hypothalamus, skeletal tissue, and central nervous system. It thickens the cervical mucus, making it difficult for sperm to enter the uterus. It also changes the endometrium, the lining of the uterus, which makes it harder for a fertilized egg to attach and grow. Norethisterone also stops the release of hormones from the pituitary, preventing ovulation and fertility. In postmenopausal women taking hormone replacement therapy, norethisterone helps reduce the risk of endometrial hyper

When to interrupt dosage

The suggested dosage of Loestrin Fe 1.5/30 is dependent upon the recognized condition, such as Atrophic, Fracture and Hormone Replacement Therapy. The magnitude of dosage is contingent upon the procedure of delivery (e.g. Oral or Tablet) specified in the following table.
Condition
Dosage
Administration
Atrophic
0.014 mg/hour, , 0.025 mg/hour, 0.5 mg, 0.1 mg, 5.0 mg, 1.0 mg, 0.35 mg, 1.5 mg, 0.8 mg, 2.7 mg, 4.8 mg, 0.75 mg, 0.4 mg, 2.25 mg, 30.0 mg, 3.0 mg
Transdermal, Patch, extended release, , Patch, extended release - Transdermal, Kit, Oral, Tablet, film coated, Tablet, film coated - Oral, Tablet, Tablet - Oral, Kit - Oral, Patch, Patch - Transdermal, Tablet, chewable, Tablet, chewable - Oral, Capsule - Oral, Capsule, Intramuscular; Oral; Topical
Endometriosis
0.014 mg/hour, , 0.025 mg/hour, 0.5 mg, 0.1 mg, 5.0 mg, 1.0 mg, 0.35 mg, 1.5 mg, 0.8 mg, 2.7 mg, 4.8 mg, 0.75 mg, 0.4 mg, 2.25 mg, 30.0 mg, 3.0 mg
Transdermal, Patch, extended release, , Patch, extended release - Transdermal, Kit, Oral, Tablet, film coated, Tablet, film coated - Oral, Tablet, Tablet - Oral, Kit - Oral, Patch, Patch - Transdermal, Tablet, chewable, Tablet, chewable - Oral, Capsule - Oral, Capsule, Intramuscular; Oral; Topical
Therapeutic procedure
0.014 mg/hour, , 0.025 mg/hour, 0.5 mg, 0.1 mg, 5.0 mg, 1.0 mg, 0.35 mg, 1.5 mg, 0.8 mg, 2.7 mg, 4.8 mg, 0.75 mg, 0.4 mg, 2.25 mg, 30.0 mg, 3.0 mg
Transdermal, Patch, extended release, , Patch, extended release - Transdermal, Kit, Oral, Tablet, film coated, Tablet, film coated - Oral, Tablet, Tablet - Oral, Kit - Oral, Patch, Patch - Transdermal, Tablet, chewable, Tablet, chewable - Oral, Capsule - Oral, Capsule, Intramuscular; Oral; Topical
Fracture
0.014 mg/hour, , 0.025 mg/hour, 0.5 mg, 0.1 mg, 5.0 mg, 1.0 mg, 0.35 mg, 1.5 mg, 0.8 mg, 2.7 mg, 4.8 mg, 0.75 mg, 0.4 mg, 2.25 mg, 30.0 mg, 3.0 mg
Transdermal, Patch, extended release, , Patch, extended release - Transdermal, Kit, Oral, Tablet, film coated, Tablet, film coated - Oral, Tablet, Tablet - Oral, Kit - Oral, Patch, Patch - Transdermal, Tablet, chewable, Tablet, chewable - Oral, Capsule - Oral, Capsule, Intramuscular; Oral; Topical
Hot flashes
0.014 mg/hour, , 0.025 mg/hour, 0.5 mg, 0.1 mg, 5.0 mg, 1.0 mg, 0.35 mg, 1.5 mg, 0.8 mg, 2.7 mg, 4.8 mg, 0.75 mg, 0.4 mg, 2.25 mg, 30.0 mg, 3.0 mg
Transdermal, Patch, extended release, , Patch, extended release - Transdermal, Kit, Oral, Tablet, film coated, Tablet, film coated - Oral, Tablet, Tablet - Oral, Kit - Oral, Patch, Patch - Transdermal, Tablet, chewable, Tablet, chewable - Oral, Capsule - Oral, Capsule, Intramuscular; Oral; Topical
Osteoporosis, Postmenopausal
0.014 mg/hour, , 0.025 mg/hour, 0.5 mg, 0.1 mg, 5.0 mg, 1.0 mg, 0.35 mg, 1.5 mg, 0.8 mg, 2.7 mg, 4.8 mg, 0.75 mg, 0.4 mg, 2.25 mg, 30.0 mg, 3.0 mg
Transdermal, Patch, extended release, , Patch, extended release - Transdermal, Kit, Oral, Tablet, film coated, Tablet, film coated - Oral, Tablet, Tablet - Oral, Kit - Oral, Patch, Patch - Transdermal, Tablet, chewable, Tablet, chewable - Oral, Capsule - Oral, Capsule, Intramuscular; Oral; Topical
Birth Control
0.014 mg/hour, , 0.025 mg/hour, 0.5 mg, 0.1 mg, 5.0 mg, 1.0 mg, 0.35 mg, 1.5 mg, 0.8 mg, 2.7 mg, 4.8 mg, 0.75 mg, 0.4 mg, 2.25 mg, 30.0 mg, 3.0 mg
Transdermal, Patch, extended release, , Patch, extended release - Transdermal, Kit, Oral, Tablet, film coated, Tablet, film coated - Oral, Tablet, Tablet - Oral, Kit - Oral, Patch, Patch - Transdermal, Tablet, chewable, Tablet, chewable - Oral, Capsule - Oral, Capsule, Intramuscular; Oral; Topical
Low Testosterone
0.014 mg/hour, , 0.025 mg/hour, 0.5 mg, 0.1 mg, 5.0 mg, 1.0 mg, 0.35 mg, 1.5 mg, 0.8 mg, 2.7 mg, 4.8 mg, 0.75 mg, 0.4 mg, 2.25 mg, 30.0 mg, 3.0 mg
Transdermal, Patch, extended release, , Patch, extended release - Transdermal, Kit, Oral, Tablet, film coated, Tablet, film coated - Oral, Tablet, Tablet - Oral, Kit - Oral, Patch, Patch - Transdermal, Tablet, chewable, Tablet, chewable - Oral, Capsule - Oral, Capsule, Intramuscular; Oral; Topical
Primary Ovarian Insufficiency
0.014 mg/hour, , 0.025 mg/hour, 0.5 mg, 0.1 mg, 5.0 mg, 1.0 mg, 0.35 mg, 1.5 mg, 0.8 mg, 2.7 mg, 4.8 mg, 0.75 mg, 0.4 mg, 2.25 mg, 30.0 mg, 3.0 mg
Transdermal, Patch, extended release, , Patch, extended release - Transdermal, Kit, Oral, Tablet, film coated, Tablet, film coated - Oral, Tablet, Tablet - Oral, Kit - Oral, Patch, Patch - Transdermal, Tablet, chewable, Tablet, chewable - Oral, Capsule - Oral, Capsule, Intramuscular; Oral; Topical
Vasomotor System
0.014 mg/hour, , 0.025 mg/hour, 0.5 mg, 0.1 mg, 5.0 mg, 1.0 mg, 0.35 mg, 1.5 mg, 0.8 mg, 2.7 mg, 4.8 mg, 0.75 mg, 0.4 mg, 2.25 mg, 30.0 mg, 3.0 mg
Transdermal, Patch, extended release, , Patch, extended release - Transdermal, Kit, Oral, Tablet, film coated, Tablet, film coated - Oral, Tablet, Tablet - Oral, Kit - Oral, Patch, Patch - Transdermal, Tablet, chewable, Tablet, chewable - Oral, Capsule - Oral, Capsule, Intramuscular; Oral; Topical
Oral Contraceptives
0.014 mg/hour, , 0.025 mg/hour, 0.5 mg, 0.1 mg, 5.0 mg, 1.0 mg, 0.35 mg, 1.5 mg, 0.8 mg, 2.7 mg, 4.8 mg, 0.75 mg, 0.4 mg, 2.25 mg, 30.0 mg, 3.0 mg
Transdermal, Patch, extended release, , Patch, extended release - Transdermal, Kit, Oral, Tablet, film coated, Tablet, film coated - Oral, Tablet, Tablet - Oral, Kit - Oral, Patch, Patch - Transdermal, Tablet, chewable, Tablet, chewable - Oral, Capsule - Oral, Capsule, Intramuscular; Oral; Topical
Hormonal Contraception
0.014 mg/hour, , 0.025 mg/hour, 0.5 mg, 0.1 mg, 5.0 mg, 1.0 mg, 0.35 mg, 1.5 mg, 0.8 mg, 2.7 mg, 4.8 mg, 0.75 mg, 0.4 mg, 2.25 mg, 30.0 mg, 3.0 mg
Transdermal, Patch, extended release, , Patch, extended release - Transdermal, Kit, Oral, Tablet, film coated, Tablet, film coated - Oral, Tablet, Tablet - Oral, Kit - Oral, Patch, Patch - Transdermal, Tablet, chewable, Tablet, chewable - Oral, Capsule - Oral, Capsule, Intramuscular; Oral; Topical
Estrogen Deprivation Symptoms
0.014 mg/hour, , 0.025 mg/hour, 0.5 mg, 0.1 mg, 5.0 mg, 1.0 mg, 0.35 mg, 1.5 mg, 0.8 mg, 2.7 mg, 4.8 mg, 0.75 mg, 0.4 mg, 2.25 mg, 30.0 mg, 3.0 mg
Transdermal, Patch, extended release, , Patch, extended release - Transdermal, Kit, Oral, Tablet, film coated, Tablet, film coated - Oral, Tablet, Tablet - Oral, Kit - Oral, Patch, Patch - Transdermal, Tablet, chewable, Tablet, chewable - Oral, Capsule - Oral, Capsule, Intramuscular; Oral; Topical
Menopause
0.014 mg/hour, , 0.025 mg/hour, 0.5 mg, 0.1 mg, 5.0 mg, 1.0 mg, 0.35 mg, 1.5 mg, 0.8 mg, 2.7 mg, 4.8 mg, 0.75 mg, 0.4 mg, 2.25 mg, 30.0 mg, 3.0 mg
Transdermal, Patch, extended release, , Patch, extended release - Transdermal, Kit, Oral, Tablet, film coated, Tablet, film coated - Oral, Tablet, Tablet - Oral, Kit - Oral, Patch, Patch - Transdermal, Tablet, chewable, Tablet, chewable - Oral, Capsule - Oral, Capsule, Intramuscular; Oral; Topical
hypoestrogenism
0.014 mg/hour, , 0.025 mg/hour, 0.5 mg, 0.1 mg, 5.0 mg, 1.0 mg, 0.35 mg, 1.5 mg, 0.8 mg, 2.7 mg, 4.8 mg, 0.75 mg, 0.4 mg, 2.25 mg, 30.0 mg, 3.0 mg
Transdermal, Patch, extended release, , Patch, extended release - Transdermal, Kit, Oral, Tablet, film coated, Tablet, film coated - Oral, Tablet, Tablet - Oral, Kit - Oral, Patch, Patch - Transdermal, Tablet, chewable, Tablet, chewable - Oral, Capsule - Oral, Capsule, Intramuscular; Oral; Topical
Endometriosis
0.014 mg/hour, , 0.025 mg/hour, 0.5 mg, 0.1 mg, 5.0 mg, 1.0 mg, 0.35 mg, 1.5 mg, 0.8 mg, 2.7 mg, 4.8 mg, 0.75 mg, 0.4 mg, 2.25 mg, 30.0 mg, 3.0 mg
Transdermal, Patch, extended release, , Patch, extended release - Transdermal, Kit, Oral, Tablet, film coated, Tablet, film coated - Oral, Tablet, Tablet - Oral, Kit - Oral, Patch, Patch - Transdermal, Tablet, chewable, Tablet, chewable - Oral, Capsule - Oral, Capsule, Intramuscular; Oral; Topical
female castration
0.014 mg/hour, , 0.025 mg/hour, 0.5 mg, 0.1 mg, 5.0 mg, 1.0 mg, 0.35 mg, 1.5 mg, 0.8 mg, 2.7 mg, 4.8 mg, 0.75 mg, 0.4 mg, 2.25 mg, 30.0 mg, 3.0 mg
Transdermal, Patch, extended release, , Patch, extended release - Transdermal, Kit, Oral, Tablet, film coated, Tablet, film coated - Oral, Tablet, Tablet - Oral, Kit - Oral, Patch, Patch - Transdermal, Tablet, chewable, Tablet, chewable - Oral, Capsule - Oral, Capsule, Intramuscular; Oral; Topical
Osteoporosis
0.014 mg/hour, , 0.025 mg/hour, 0.5 mg, 0.1 mg, 5.0 mg, 1.0 mg, 0.35 mg, 1.5 mg, 0.8 mg, 2.7 mg, 4.8 mg, 0.75 mg, 0.4 mg, 2.25 mg, 30.0 mg, 3.0 mg
Transdermal, Patch, extended release, , Patch, extended release - Transdermal, Kit, Oral, Tablet, film coated, Tablet, film coated - Oral, Tablet, Tablet - Oral, Kit - Oral, Patch, Patch - Transdermal, Tablet, chewable, Tablet, chewable - Oral, Capsule - Oral, Capsule, Intramuscular; Oral; Topical
Hormone Replacement Therapy
0.014 mg/hour, , 0.025 mg/hour, 0.5 mg, 0.1 mg, 5.0 mg, 1.0 mg, 0.35 mg, 1.5 mg, 0.8 mg, 2.7 mg, 4.8 mg, 0.75 mg, 0.4 mg, 2.25 mg, 30.0 mg, 3.0 mg
Transdermal, Patch, extended release, , Patch, extended release - Transdermal, Kit, Oral, Tablet, film coated, Tablet, film coated - Oral, Tablet, Tablet - Oral, Kit - Oral, Patch, Patch - Transdermal, Tablet, chewable, Tablet, chewable - Oral, Capsule - Oral, Capsule, Intramuscular; Oral; Topical

Warnings

Loestrin Fe 1.5/30 Contraindications
Condition
Risk Level
Notes
Liver Diseases
Do Not Combine
Thrombophilia
Do Not Combine
Vaginal Hemorrhage
Do Not Combine
Malignant Neoplasms
Do Not Combine
Benign hepatic neoplasm
Do Not Combine
Breast Cancer
Do Not Combine
Thromboembolism
Do Not Combine
Severe Hypersensitivity Reactions
Do Not Combine
Norethisterone may interact with Pulse Frequency
There are 20 known major drug interactions with Loestrin Fe 1.5/30.
Common Loestrin Fe 1.5/30 Drug Interactions
Drug Name
Risk Level
Description
Astemizole
Major
The metabolism of Astemizole can be decreased when combined with Norethisterone.
Axitinib
Major
The metabolism of Axitinib can be decreased when combined with Norethisterone.
Cabazitaxel
Major
The metabolism of Cabazitaxel can be decreased when combined with Norethisterone.
Clomipramine
Major
The metabolism of Clomipramine can be increased when combined with Norethisterone.
Copanlisib
Major
The metabolism of Copanlisib can be decreased when combined with Norethisterone.
Loestrin Fe 1.5/30 Toxicity & Overdose RiskThe lowest dose of oral contraceptives that caused toxicity in mice was 6g/kg, and the lowest dose that caused toxicity in women was 42mg/kg. There have been no reports of serious consequences from taking too much of this medication, including when taken by children. However, overdosing may cause nausea and vomiting.

Loestrin Fe 1.5/30 Novel Uses: Which Conditions Have a Clinical Trial Featuring Loestrin Fe 1.5/30?

Currently, there are 160 active clinical trials assessing the potential of Loestrin Fe 1.5/30 to provide Birth Control, Atrophy Prevention and Low Testosterone Relief.
Condition
Clinical Trials
Trial Phases
Osteoporosis
32 Actively Recruiting
Not Applicable, Phase 2, Phase 4, Phase 1, Phase 3
Endometriosis
34 Actively Recruiting
Early Phase 1, Phase 2, Not Applicable, Phase 3, Phase 4, Phase 1
Atrophic
4 Actively Recruiting
Phase 4, Not Applicable
Birth Control
28 Actively Recruiting
Not Applicable, Phase 3, Phase 4, Early Phase 1
Low Testosterone
6 Actively Recruiting
Phase 4, Phase 2, Phase 1
Endometriosis
3 Actively Recruiting
Phase 4, Not Applicable
Oral Contraceptives
2 Actively Recruiting
Not Applicable
Hot flashes
13 Actively Recruiting
Phase 1, Phase 2, Not Applicable, Phase 4, Early Phase 1
Osteoporosis, Postmenopausal
0 Actively Recruiting
Estrogen Deprivation Symptoms
0 Actively Recruiting
female castration
0 Actively Recruiting
Hormone Replacement Therapy
0 Actively Recruiting
Hormonal Contraception
0 Actively Recruiting
hypoestrogenism
1 Actively Recruiting
Phase 4
Fracture
0 Actively Recruiting
Vasomotor System
0 Actively Recruiting
Primary Ovarian Insufficiency
0 Actively Recruiting
Therapeutic procedure
0 Actively Recruiting
Menopause
0 Actively Recruiting

Loestrin Fe 1.5/30 Reviews: What are patients saying about Loestrin Fe 1.5/30?

5Patient Review
7/22/2011
Loestrin Fe 1.5/30 for Absence of Menstrual Periods
I was having issues with decreased libido on other birth control, so my doctor switched me to this. It's only been two days, but I'm already feeling great! My sex drive is back and I'm more aroused than ever. Let's hope it stays like this!
5Patient Review
5/28/2009
Loestrin Fe 1.5/30 for Birth Control
5Patient Review
8/23/2009
Loestrin Fe 1.5/30 for Abnormally Long or Heavy Periods
4.7Patient Review
7/29/2010
Loestrin Fe 1.5/30 for Birth Control
The pill is low dose, but I didn't have any sex drive, felt dry vaginally, got acne, and was moody.
4.7Patient Review
6/20/2013
Loestrin Fe 1.5/30 for Birth Control
Loestrin has effectively regulated my (previously irregular) flow, but I have been experiencing abdominal/pelvic pain and heavy bleeding since starting my third pack. This has caused me a great deal of discomfort and makes it difficult to sleep through the night. Doctors say this may last another month or so.
3.7Patient Review
4/19/2012
Loestrin Fe 1.5/30 for Abnormally Long or Heavy Periods
Switched to the generic brand of loestrin fe 1.5/30 after a year on loestrin fe with no problems. However, immediately noticed mood swings and constant hunger. Bloated and swelling in hands and feet.
3.7Patient Review
1/19/2012
Loestrin Fe 1.5/30 for Birth Control
Initially, this medication helped with my spotting issue. However, after about three months of use, I started to experience breakouts and a total lack of sex drive.
3.3Patient Review
10/19/2009
Loestrin Fe 1.5/30 for Birth Control
Though I experienced some brown patches on my skin, this pill helped to lighten my periods from 7-10 days down to only 1-3. Additionally, I didn't have much nausea compared to other birth control pills I've taken in the past.
3Patient Review
8/8/2014
Loestrin Fe 1.5/30 for Birth Control
The nausea this medicine caused was unlike anything I've ever experienced. I had to stop taking it before finishing the first week because the waves of nausea were so bad that I nearly vomited on those around me. It also caused a loss of sex drive, depression, and sleepiness.
2.3Patient Review
9/22/2014
Loestrin Fe 1.5/30 for Birth Control
I switched to this pill because the pill I was on previously caused me to have very tender breasts. This pill took the tender breasts away, but caused pretty bad acne for a few months and very inconsistent periods. The periods are light, but I never know when they are coming. I have now been on this pill 10 months and have had 2 periods a month for the last 3 months.
image of drug pills surrounding a glass of water symbolizing drug consumption

Patient Q&A Section about loestrin fe 1.5/30

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Is loestrin 1.5 30 discontinued?

"The availability of Generic Loestrin Fe 1.5/30 was last updated on Aug 10, 2022."

Answered by AI

What is the difference between loestrin 1.5 30 and 1 20?

"Type: Combined Oral Contraceptive

Available in 1/20, 1.5/30

Description:

LOESTRIN is a combined oral contraceptive (COC) that contains two active ingredients, norethindrone acetate and ethinyl estradiol. Norethindrone acetate is a progestin, and ethinyl estradiol is an estrogen. Both of these hormones work together to prevent pregnancy by inhibiting ovulation (the release of an egg from the ovary).

The active ingredients in LOESTRIN are available in two different doses: 1/20 and 1.5/30. The 1/20 tablet contains 1 mg of norethindrone acetate and 20 mcg of ethinyl estradiol. The 1.5/30 tablet contains 1.5 mg of norethindrone acetate and 30 mcg of ethinyl estradiol.

In addition to the active ingredients, each tablet also contains 75 mg of ferrous fumarate. Ferrous fumarate is a type of iron that is needed for the production of red blood cells.

LOESTRIN is a combined oral contraceptive (C"

Answered by AI

What does loestrin 1.5 30 mean?

"The Loestrin 1.5/30 contraceptive pill contains a combination of ethinyl estradiol and norethindrone hormones, which work together to prevent pregnancy. When taken correctly, this birth control pill is an effective method of contraception."

Answered by AI

Is loestrin 1.5 30 A combination pill?

"Iron is important in the production of hemoglobin, which carries oxygen in the blood.

This combination hormone medication is used to prevent pregnancy. It contains 2 hormones: norethindrone (a progestin) and ethinyl estradiol (an estrogen), as well as a small amount of iron (ferrous fumarate) in each of the 7 inactive tablets taken during the fourth week. Iron is important in the production of hemoglobin, which carries oxygen in the blood."

Answered by AI

Clinical Trials for Loestrin Fe 1.5/30

Have you considered Loestrin Fe 1.5/30 clinical trials? We made a collection of clinical trials featuring Loestrin Fe 1.5/30, we think they might fit your search criteria.
Have you considered Loestrin Fe 1.5/30 clinical trials? We made a collection of clinical trials featuring Loestrin Fe 1.5/30, we think they might fit your search criteria.
Have you considered Loestrin Fe 1.5/30 clinical trials? We made a collection of clinical trials featuring Loestrin Fe 1.5/30, we think they might fit your search criteria.
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