Mephyton

Jaundice, Obstructive, long-acting anticoagulant rodenticides, Vitamin K Deficiency + 17 more
Treatment
10 FDA approvals
17 Active Studies for Mephyton

What is Mephyton

PhylloquinoneThe Generic name of this drug
Treatment SummaryVitamin K1 (also known as phylloquinone or phytonadione) is a fat-soluble vitamin that helps the body form clotting factors II, VII, IX, and X. It is used to treat clotting disorders caused by a lack of vitamin K. This vitamin has been available since 1939 and was approved by the FDA before 1955.
Mephytonis the brand name
image of different drug pills on a surface
Mephyton Overview & Background
Brand Name
Generic Name
First FDA Approval
How many FDA approvals?
Mephyton
Phylloquinone
1955
65

Approved as Treatment by the FDA

Phylloquinone, also known as Mephyton, is approved by the FDA for 10 uses including Jaundice, Obstructive and Hypoprothrombinemia .
Jaundice, Obstructive
Used to treat Jaundice, Obstructive in combination with Taurocholic acid
Hypoprothrombinemia
Fistula, Biliary
Used to treat Fistula, Biliary in combination with Taurocholic acid
antibacterial therapy
Biliary Fistula
Used to treat Fistula, Biliary in combination with Taurocholic acid
hemorrhagic disease of the newborn
Hypoprothrombinemias
Jaundice, Obstructive
Used to treat Jaundice, Obstructive in combination with Taurocholic acid
Hemorrhagic Disease of Newborn
Salicylate

Effectiveness

How Mephyton Affects PatientsPhylloquinone is a vitamin K used to treat problems with blood clotting due to a lack of or reduced activity of vitamin K. It stays in the body for a long time and is safe to take in large doses. People taking this medication should have their prothrombin time monitored, and healthcare professionals should be aware of the risk of allergic reactions with injections.
How Mephyton works in the bodyVitamin K helps the body form blood clots by helping clotting proteins bind to calcium ions. This allows them to become active and be released into the blood, which helps stop bleeding. Vitamin K might also help prevent joint calcification, increased bone density, and reducing the risk of vascular calcification. These benefits are still being studied.

When to interrupt dosage

The suggested portion of Mephyton is contingent upon the diagnosed condition, like Sprue, Vitamin supplementation and Ulcerative Colitis. The measure of dosage is contingent upon the method of delivery outlined in the table beneath.
Condition
Dosage
Administration
Vitamin supplementation
, 5.0 mg, 10.0 mg/mL, 2.0 mg/mL, 1.0 mg, 0.2 mg/mL, 0.015 mg/mL, 0.15 mg/mL, 0.2 mg, 0.02 mg, 0.08 mg, 0.15 mg, 0.02 mg/mL, 0.1 mg/mL
, Oral, Tablet, Tablet - Oral, Parenteral, Injection, emulsion, Injection, emulsion - Parenteral, Intramuscular; Parenteral; Subcutaneous, Injection, solution, Intramuscular; Intravenous; Subcutaneous, Injection, solution - Intramuscular; Intravenous; Subcutaneous, Injection, emulsion - Intramuscular; Intravenous; Subcutaneous, Solution, Solution - Intramuscular; Intravenous; Subcutaneous, Emulsion, Emulsion - Intramuscular; Intravenous; Subcutaneous, Intramuscular, Liquid - Intramuscular, Liquid, Intravenous, Injection, powder, lyophilized, for solution - Intravenous, Injection, solution - Intravenous, Capsule, Capsule - Oral, Solution - Parenteral, Injection, powder, lyophilized, for solution, Injection, emulsion - Intramuscular; Parenteral; Subcutaneous, Liquid - Intravenous, Kit, Kit - Oral, Injection, Injection - Intravenous, Solution / drops, Solution / drops - Oral
long-acting anticoagulant rodenticides
, 5.0 mg, 10.0 mg/mL, 2.0 mg/mL, 1.0 mg, 0.2 mg/mL, 0.015 mg/mL, 0.15 mg/mL, 0.2 mg, 0.02 mg, 0.08 mg, 0.15 mg, 0.02 mg/mL, 0.1 mg/mL
, Oral, Tablet, Tablet - Oral, Parenteral, Injection, emulsion, Injection, emulsion - Parenteral, Intramuscular; Parenteral; Subcutaneous, Injection, solution, Intramuscular; Intravenous; Subcutaneous, Injection, solution - Intramuscular; Intravenous; Subcutaneous, Injection, emulsion - Intramuscular; Intravenous; Subcutaneous, Solution, Solution - Intramuscular; Intravenous; Subcutaneous, Emulsion, Emulsion - Intramuscular; Intravenous; Subcutaneous, Intramuscular, Liquid - Intramuscular, Liquid, Intravenous, Injection, powder, lyophilized, for solution - Intravenous, Injection, solution - Intravenous, Capsule, Capsule - Oral, Solution - Parenteral, Injection, powder, lyophilized, for solution, Injection, emulsion - Intramuscular; Parenteral; Subcutaneous, Liquid - Intravenous, Kit, Kit - Oral, Injection, Injection - Intravenous, Solution / drops, Solution / drops - Oral
hemorrhagic disease of the newborn
, 5.0 mg, 10.0 mg/mL, 2.0 mg/mL, 1.0 mg, 0.2 mg/mL, 0.015 mg/mL, 0.15 mg/mL, 0.2 mg, 0.02 mg, 0.08 mg, 0.15 mg, 0.02 mg/mL, 0.1 mg/mL
, Oral, Tablet, Tablet - Oral, Parenteral, Injection, emulsion, Injection, emulsion - Parenteral, Intramuscular; Parenteral; Subcutaneous, Injection, solution, Intramuscular; Intravenous; Subcutaneous, Injection, solution - Intramuscular; Intravenous; Subcutaneous, Injection, emulsion - Intramuscular; Intravenous; Subcutaneous, Solution, Solution - Intramuscular; Intravenous; Subcutaneous, Emulsion, Emulsion - Intramuscular; Intravenous; Subcutaneous, Intramuscular, Liquid - Intramuscular, Liquid, Intravenous, Injection, powder, lyophilized, for solution - Intravenous, Injection, solution - Intravenous, Capsule, Capsule - Oral, Solution - Parenteral, Injection, powder, lyophilized, for solution, Injection, emulsion - Intramuscular; Parenteral; Subcutaneous, Liquid - Intravenous, Kit, Kit - Oral, Injection, Injection - Intravenous, Solution / drops, Solution / drops - Oral
Ulcerative Colitis
, 5.0 mg, 10.0 mg/mL, 2.0 mg/mL, 1.0 mg, 0.2 mg/mL, 0.015 mg/mL, 0.15 mg/mL, 0.2 mg, 0.02 mg, 0.08 mg, 0.15 mg, 0.02 mg/mL, 0.1 mg/mL
, Oral, Tablet, Tablet - Oral, Parenteral, Injection, emulsion, Injection, emulsion - Parenteral, Intramuscular; Parenteral; Subcutaneous, Injection, solution, Intramuscular; Intravenous; Subcutaneous, Injection, solution - Intramuscular; Intravenous; Subcutaneous, Injection, emulsion - Intramuscular; Intravenous; Subcutaneous, Solution, Solution - Intramuscular; Intravenous; Subcutaneous, Emulsion, Emulsion - Intramuscular; Intravenous; Subcutaneous, Intramuscular, Liquid - Intramuscular, Liquid, Intravenous, Injection, powder, lyophilized, for solution - Intravenous, Injection, solution - Intravenous, Capsule, Capsule - Oral, Solution - Parenteral, Injection, powder, lyophilized, for solution, Injection, emulsion - Intramuscular; Parenteral; Subcutaneous, Liquid - Intravenous, Kit, Kit - Oral, Injection, Injection - Intravenous, Solution / drops, Solution / drops - Oral
Biliary Fistula
, 5.0 mg, 10.0 mg/mL, 2.0 mg/mL, 1.0 mg, 0.2 mg/mL, 0.015 mg/mL, 0.15 mg/mL, 0.2 mg, 0.02 mg, 0.08 mg, 0.15 mg, 0.02 mg/mL, 0.1 mg/mL
, Oral, Tablet, Tablet - Oral, Parenteral, Injection, emulsion, Injection, emulsion - Parenteral, Intramuscular; Parenteral; Subcutaneous, Injection, solution, Intramuscular; Intravenous; Subcutaneous, Injection, solution - Intramuscular; Intravenous; Subcutaneous, Injection, emulsion - Intramuscular; Intravenous; Subcutaneous, Solution, Solution - Intramuscular; Intravenous; Subcutaneous, Emulsion, Emulsion - Intramuscular; Intravenous; Subcutaneous, Intramuscular, Liquid - Intramuscular, Liquid, Intravenous, Injection, powder, lyophilized, for solution - Intravenous, Injection, solution - Intravenous, Capsule, Capsule - Oral, Solution - Parenteral, Injection, powder, lyophilized, for solution, Injection, emulsion - Intramuscular; Parenteral; Subcutaneous, Liquid - Intravenous, Kit, Kit - Oral, Injection, Injection - Intravenous, Solution / drops, Solution / drops - Oral
Crohn Disease
, 5.0 mg, 10.0 mg/mL, 2.0 mg/mL, 1.0 mg, 0.2 mg/mL, 0.015 mg/mL, 0.15 mg/mL, 0.2 mg, 0.02 mg, 0.08 mg, 0.15 mg, 0.02 mg/mL, 0.1 mg/mL
, Oral, Tablet, Tablet - Oral, Parenteral, Injection, emulsion, Injection, emulsion - Parenteral, Intramuscular; Parenteral; Subcutaneous, Injection, solution, Intramuscular; Intravenous; Subcutaneous, Injection, solution - Intramuscular; Intravenous; Subcutaneous, Injection, emulsion - Intramuscular; Intravenous; Subcutaneous, Solution, Solution - Intramuscular; Intravenous; Subcutaneous, Emulsion, Emulsion - Intramuscular; Intravenous; Subcutaneous, Intramuscular, Liquid - Intramuscular, Liquid, Intravenous, Injection, powder, lyophilized, for solution - Intravenous, Injection, solution - Intravenous, Capsule, Capsule - Oral, Solution - Parenteral, Injection, powder, lyophilized, for solution, Injection, emulsion - Intramuscular; Parenteral; Subcutaneous, Liquid - Intravenous, Kit, Kit - Oral, Injection, Injection - Intravenous, Solution / drops, Solution / drops - Oral
Anticoagulant Therapy
, 5.0 mg, 10.0 mg/mL, 2.0 mg/mL, 1.0 mg, 0.2 mg/mL, 0.015 mg/mL, 0.15 mg/mL, 0.2 mg, 0.02 mg, 0.08 mg, 0.15 mg, 0.02 mg/mL, 0.1 mg/mL
, Oral, Tablet, Tablet - Oral, Parenteral, Injection, emulsion, Injection, emulsion - Parenteral, Intramuscular; Parenteral; Subcutaneous, Injection, solution, Intramuscular; Intravenous; Subcutaneous, Injection, solution - Intramuscular; Intravenous; Subcutaneous, Injection, emulsion - Intramuscular; Intravenous; Subcutaneous, Solution, Solution - Intramuscular; Intravenous; Subcutaneous, Emulsion, Emulsion - Intramuscular; Intravenous; Subcutaneous, Intramuscular, Liquid - Intramuscular, Liquid, Intravenous, Injection, powder, lyophilized, for solution - Intravenous, Injection, solution - Intravenous, Capsule, Capsule - Oral, Solution - Parenteral, Injection, powder, lyophilized, for solution, Injection, emulsion - Intramuscular; Parenteral; Subcutaneous, Liquid - Intravenous, Kit, Kit - Oral, Injection, Injection - Intravenous, Solution / drops, Solution / drops - Oral
Blood Coagulation Disorders
, 5.0 mg, 10.0 mg/mL, 2.0 mg/mL, 1.0 mg, 0.2 mg/mL, 0.015 mg/mL, 0.15 mg/mL, 0.2 mg, 0.02 mg, 0.08 mg, 0.15 mg, 0.02 mg/mL, 0.1 mg/mL
, Oral, Tablet, Tablet - Oral, Parenteral, Injection, emulsion, Injection, emulsion - Parenteral, Intramuscular; Parenteral; Subcutaneous, Injection, solution, Intramuscular; Intravenous; Subcutaneous, Injection, solution - Intramuscular; Intravenous; Subcutaneous, Injection, emulsion - Intramuscular; Intravenous; Subcutaneous, Solution, Solution - Intramuscular; Intravenous; Subcutaneous, Emulsion, Emulsion - Intramuscular; Intravenous; Subcutaneous, Intramuscular, Liquid - Intramuscular, Liquid, Intravenous, Injection, powder, lyophilized, for solution - Intravenous, Injection, solution - Intravenous, Capsule, Capsule - Oral, Solution - Parenteral, Injection, powder, lyophilized, for solution, Injection, emulsion - Intramuscular; Parenteral; Subcutaneous, Liquid - Intravenous, Kit, Kit - Oral, Injection, Injection - Intravenous, Solution / drops, Solution / drops - Oral
Celiac Disease
, 5.0 mg, 10.0 mg/mL, 2.0 mg/mL, 1.0 mg, 0.2 mg/mL, 0.015 mg/mL, 0.15 mg/mL, 0.2 mg, 0.02 mg, 0.08 mg, 0.15 mg, 0.02 mg/mL, 0.1 mg/mL
, Oral, Tablet, Tablet - Oral, Parenteral, Injection, emulsion, Injection, emulsion - Parenteral, Intramuscular; Parenteral; Subcutaneous, Injection, solution, Intramuscular; Intravenous; Subcutaneous, Injection, solution - Intramuscular; Intravenous; Subcutaneous, Injection, emulsion - Intramuscular; Intravenous; Subcutaneous, Solution, Solution - Intramuscular; Intravenous; Subcutaneous, Emulsion, Emulsion - Intramuscular; Intravenous; Subcutaneous, Intramuscular, Liquid - Intramuscular, Liquid, Intravenous, Injection, powder, lyophilized, for solution - Intravenous, Injection, solution - Intravenous, Capsule, Capsule - Oral, Solution - Parenteral, Injection, powder, lyophilized, for solution, Injection, emulsion - Intramuscular; Parenteral; Subcutaneous, Liquid - Intravenous, Kit, Kit - Oral, Injection, Injection - Intravenous, Solution / drops, Solution / drops - Oral
Vitamin supplementation therapy
, 5.0 mg, 10.0 mg/mL, 2.0 mg/mL, 1.0 mg, 0.2 mg/mL, 0.015 mg/mL, 0.15 mg/mL, 0.2 mg, 0.02 mg, 0.08 mg, 0.15 mg, 0.02 mg/mL, 0.1 mg/mL
, Oral, Tablet, Tablet - Oral, Parenteral, Injection, emulsion, Injection, emulsion - Parenteral, Intramuscular; Parenteral; Subcutaneous, Injection, solution, Intramuscular; Intravenous; Subcutaneous, Injection, solution - Intramuscular; Intravenous; Subcutaneous, Injection, emulsion - Intramuscular; Intravenous; Subcutaneous, Solution, Solution - Intramuscular; Intravenous; Subcutaneous, Emulsion, Emulsion - Intramuscular; Intravenous; Subcutaneous, Intramuscular, Liquid - Intramuscular, Liquid, Intravenous, Injection, powder, lyophilized, for solution - Intravenous, Injection, solution - Intravenous, Capsule, Capsule - Oral, Solution - Parenteral, Injection, powder, lyophilized, for solution, Injection, emulsion - Intramuscular; Parenteral; Subcutaneous, Liquid - Intravenous, Kit, Kit - Oral, Injection, Injection - Intravenous, Solution / drops, Solution / drops - Oral
vitamin K
, 5.0 mg, 10.0 mg/mL, 2.0 mg/mL, 1.0 mg, 0.2 mg/mL, 0.015 mg/mL, 0.15 mg/mL, 0.2 mg, 0.02 mg, 0.08 mg, 0.15 mg, 0.02 mg/mL, 0.1 mg/mL
, Oral, Tablet, Tablet - Oral, Parenteral, Injection, emulsion, Injection, emulsion - Parenteral, Intramuscular; Parenteral; Subcutaneous, Injection, solution, Intramuscular; Intravenous; Subcutaneous, Injection, solution - Intramuscular; Intravenous; Subcutaneous, Injection, emulsion - Intramuscular; Intravenous; Subcutaneous, Solution, Solution - Intramuscular; Intravenous; Subcutaneous, Emulsion, Emulsion - Intramuscular; Intravenous; Subcutaneous, Intramuscular, Liquid - Intramuscular, Liquid, Intravenous, Injection, powder, lyophilized, for solution - Intravenous, Injection, solution - Intravenous, Capsule, Capsule - Oral, Solution - Parenteral, Injection, powder, lyophilized, for solution, Injection, emulsion - Intramuscular; Parenteral; Subcutaneous, Liquid - Intravenous, Kit, Kit - Oral, Injection, Injection - Intravenous, Solution / drops, Solution / drops - Oral
Jaundice, Obstructive
, 5.0 mg, 10.0 mg/mL, 2.0 mg/mL, 1.0 mg, 0.2 mg/mL, 0.015 mg/mL, 0.15 mg/mL, 0.2 mg, 0.02 mg, 0.08 mg, 0.15 mg, 0.02 mg/mL, 0.1 mg/mL
, Oral, Tablet, Tablet - Oral, Parenteral, Injection, emulsion, Injection, emulsion - Parenteral, Intramuscular; Parenteral; Subcutaneous, Injection, solution, Intramuscular; Intravenous; Subcutaneous, Injection, solution - Intramuscular; Intravenous; Subcutaneous, Injection, emulsion - Intramuscular; Intravenous; Subcutaneous, Solution, Solution - Intramuscular; Intravenous; Subcutaneous, Emulsion, Emulsion - Intramuscular; Intravenous; Subcutaneous, Intramuscular, Liquid - Intramuscular, Liquid, Intravenous, Injection, powder, lyophilized, for solution - Intravenous, Injection, solution - Intravenous, Capsule, Capsule - Oral, Solution - Parenteral, Injection, powder, lyophilized, for solution, Injection, emulsion - Intramuscular; Parenteral; Subcutaneous, Liquid - Intravenous, Kit, Kit - Oral, Injection, Injection - Intravenous, Solution / drops, Solution / drops - Oral
Vitamin K Deficiency
, 5.0 mg, 10.0 mg/mL, 2.0 mg/mL, 1.0 mg, 0.2 mg/mL, 0.015 mg/mL, 0.15 mg/mL, 0.2 mg, 0.02 mg, 0.08 mg, 0.15 mg, 0.02 mg/mL, 0.1 mg/mL
, Oral, Tablet, Tablet - Oral, Parenteral, Injection, emulsion, Injection, emulsion - Parenteral, Intramuscular; Parenteral; Subcutaneous, Injection, solution, Intramuscular; Intravenous; Subcutaneous, Injection, solution - Intramuscular; Intravenous; Subcutaneous, Injection, emulsion - Intramuscular; Intravenous; Subcutaneous, Solution, Solution - Intramuscular; Intravenous; Subcutaneous, Emulsion, Emulsion - Intramuscular; Intravenous; Subcutaneous, Intramuscular, Liquid - Intramuscular, Liquid, Intravenous, Injection, powder, lyophilized, for solution - Intravenous, Injection, solution - Intravenous, Capsule, Capsule - Oral, Solution - Parenteral, Injection, powder, lyophilized, for solution, Injection, emulsion - Intramuscular; Parenteral; Subcutaneous, Liquid - Intravenous, Kit, Kit - Oral, Injection, Injection - Intravenous, Solution / drops, Solution / drops - Oral
Hypoprothrombinemias
, 5.0 mg, 10.0 mg/mL, 2.0 mg/mL, 1.0 mg, 0.2 mg/mL, 0.015 mg/mL, 0.15 mg/mL, 0.2 mg, 0.02 mg, 0.08 mg, 0.15 mg, 0.02 mg/mL, 0.1 mg/mL
, Oral, Tablet, Tablet - Oral, Parenteral, Injection, emulsion, Injection, emulsion - Parenteral, Intramuscular; Parenteral; Subcutaneous, Injection, solution, Intramuscular; Intravenous; Subcutaneous, Injection, solution - Intramuscular; Intravenous; Subcutaneous, Injection, emulsion - Intramuscular; Intravenous; Subcutaneous, Solution, Solution - Intramuscular; Intravenous; Subcutaneous, Emulsion, Emulsion - Intramuscular; Intravenous; Subcutaneous, Intramuscular, Liquid - Intramuscular, Liquid, Intravenous, Injection, powder, lyophilized, for solution - Intravenous, Injection, solution - Intravenous, Capsule, Capsule - Oral, Solution - Parenteral, Injection, powder, lyophilized, for solution, Injection, emulsion - Intramuscular; Parenteral; Subcutaneous, Liquid - Intravenous, Kit, Kit - Oral, Injection, Injection - Intravenous, Solution / drops, Solution / drops - Oral
Intestinal resection
, 5.0 mg, 10.0 mg/mL, 2.0 mg/mL, 1.0 mg, 0.2 mg/mL, 0.015 mg/mL, 0.15 mg/mL, 0.2 mg, 0.02 mg, 0.08 mg, 0.15 mg, 0.02 mg/mL, 0.1 mg/mL
, Oral, Tablet, Tablet - Oral, Parenteral, Injection, emulsion, Injection, emulsion - Parenteral, Intramuscular; Parenteral; Subcutaneous, Injection, solution, Intramuscular; Intravenous; Subcutaneous, Injection, solution - Intramuscular; Intravenous; Subcutaneous, Injection, emulsion - Intramuscular; Intravenous; Subcutaneous, Solution, Solution - Intramuscular; Intravenous; Subcutaneous, Emulsion, Emulsion - Intramuscular; Intravenous; Subcutaneous, Intramuscular, Liquid - Intramuscular, Liquid, Intravenous, Injection, powder, lyophilized, for solution - Intravenous, Injection, solution - Intravenous, Capsule, Capsule - Oral, Solution - Parenteral, Injection, powder, lyophilized, for solution, Injection, emulsion - Intramuscular; Parenteral; Subcutaneous, Liquid - Intravenous, Kit, Kit - Oral, Injection, Injection - Intravenous, Solution / drops, Solution / drops - Oral
Hemorrhagic Disease of Newborn
, 5.0 mg, 10.0 mg/mL, 2.0 mg/mL, 1.0 mg, 0.2 mg/mL, 0.015 mg/mL, 0.15 mg/mL, 0.2 mg, 0.02 mg, 0.08 mg, 0.15 mg, 0.02 mg/mL, 0.1 mg/mL
, Oral, Tablet, Tablet - Oral, Parenteral, Injection, emulsion, Injection, emulsion - Parenteral, Intramuscular; Parenteral; Subcutaneous, Injection, solution, Intramuscular; Intravenous; Subcutaneous, Injection, solution - Intramuscular; Intravenous; Subcutaneous, Injection, emulsion - Intramuscular; Intravenous; Subcutaneous, Solution, Solution - Intramuscular; Intravenous; Subcutaneous, Emulsion, Emulsion - Intramuscular; Intravenous; Subcutaneous, Intramuscular, Liquid - Intramuscular, Liquid, Intravenous, Injection, powder, lyophilized, for solution - Intravenous, Injection, solution - Intravenous, Capsule, Capsule - Oral, Solution - Parenteral, Injection, powder, lyophilized, for solution, Injection, emulsion - Intramuscular; Parenteral; Subcutaneous, Liquid - Intravenous, Kit, Kit - Oral, Injection, Injection - Intravenous, Solution / drops, Solution / drops - Oral
Salicylate
, 5.0 mg, 10.0 mg/mL, 2.0 mg/mL, 1.0 mg, 0.2 mg/mL, 0.015 mg/mL, 0.15 mg/mL, 0.2 mg, 0.02 mg, 0.08 mg, 0.15 mg, 0.02 mg/mL, 0.1 mg/mL
, Oral, Tablet, Tablet - Oral, Parenteral, Injection, emulsion, Injection, emulsion - Parenteral, Intramuscular; Parenteral; Subcutaneous, Injection, solution, Intramuscular; Intravenous; Subcutaneous, Injection, solution - Intramuscular; Intravenous; Subcutaneous, Injection, emulsion - Intramuscular; Intravenous; Subcutaneous, Solution, Solution - Intramuscular; Intravenous; Subcutaneous, Emulsion, Emulsion - Intramuscular; Intravenous; Subcutaneous, Intramuscular, Liquid - Intramuscular, Liquid, Intravenous, Injection, powder, lyophilized, for solution - Intravenous, Injection, solution - Intravenous, Capsule, Capsule - Oral, Solution - Parenteral, Injection, powder, lyophilized, for solution, Injection, emulsion - Intramuscular; Parenteral; Subcutaneous, Liquid - Intravenous, Kit, Kit - Oral, Injection, Injection - Intravenous, Solution / drops, Solution / drops - Oral
Cystic Fibrosis
, 5.0 mg, 10.0 mg/mL, 2.0 mg/mL, 1.0 mg, 0.2 mg/mL, 0.015 mg/mL, 0.15 mg/mL, 0.2 mg, 0.02 mg, 0.08 mg, 0.15 mg, 0.02 mg/mL, 0.1 mg/mL
, Oral, Tablet, Tablet - Oral, Parenteral, Injection, emulsion, Injection, emulsion - Parenteral, Intramuscular; Parenteral; Subcutaneous, Injection, solution, Intramuscular; Intravenous; Subcutaneous, Injection, solution - Intramuscular; Intravenous; Subcutaneous, Injection, emulsion - Intramuscular; Intravenous; Subcutaneous, Solution, Solution - Intramuscular; Intravenous; Subcutaneous, Emulsion, Emulsion - Intramuscular; Intravenous; Subcutaneous, Intramuscular, Liquid - Intramuscular, Liquid, Intravenous, Injection, powder, lyophilized, for solution - Intravenous, Injection, solution - Intravenous, Capsule, Capsule - Oral, Solution - Parenteral, Injection, powder, lyophilized, for solution, Injection, emulsion - Intramuscular; Parenteral; Subcutaneous, Liquid - Intravenous, Kit, Kit - Oral, Injection, Injection - Intravenous, Solution / drops, Solution / drops - Oral
Celiac Disease
, 5.0 mg, 10.0 mg/mL, 2.0 mg/mL, 1.0 mg, 0.2 mg/mL, 0.015 mg/mL, 0.15 mg/mL, 0.2 mg, 0.02 mg, 0.08 mg, 0.15 mg, 0.02 mg/mL, 0.1 mg/mL
, Oral, Tablet, Tablet - Oral, Parenteral, Injection, emulsion, Injection, emulsion - Parenteral, Intramuscular; Parenteral; Subcutaneous, Injection, solution, Intramuscular; Intravenous; Subcutaneous, Injection, solution - Intramuscular; Intravenous; Subcutaneous, Injection, emulsion - Intramuscular; Intravenous; Subcutaneous, Solution, Solution - Intramuscular; Intravenous; Subcutaneous, Emulsion, Emulsion - Intramuscular; Intravenous; Subcutaneous, Intramuscular, Liquid - Intramuscular, Liquid, Intravenous, Injection, powder, lyophilized, for solution - Intravenous, Injection, solution - Intravenous, Capsule, Capsule - Oral, Solution - Parenteral, Injection, powder, lyophilized, for solution, Injection, emulsion - Intramuscular; Parenteral; Subcutaneous, Liquid - Intravenous, Kit, Kit - Oral, Injection, Injection - Intravenous, Solution / drops, Solution / drops - Oral
antibacterial therapy
, 5.0 mg, 10.0 mg/mL, 2.0 mg/mL, 1.0 mg, 0.2 mg/mL, 0.015 mg/mL, 0.15 mg/mL, 0.2 mg, 0.02 mg, 0.08 mg, 0.15 mg, 0.02 mg/mL, 0.1 mg/mL
, Oral, Tablet, Tablet - Oral, Parenteral, Injection, emulsion, Injection, emulsion - Parenteral, Intramuscular; Parenteral; Subcutaneous, Injection, solution, Intramuscular; Intravenous; Subcutaneous, Injection, solution - Intramuscular; Intravenous; Subcutaneous, Injection, emulsion - Intramuscular; Intravenous; Subcutaneous, Solution, Solution - Intramuscular; Intravenous; Subcutaneous, Emulsion, Emulsion - Intramuscular; Intravenous; Subcutaneous, Intramuscular, Liquid - Intramuscular, Liquid, Intravenous, Injection, powder, lyophilized, for solution - Intravenous, Injection, solution - Intravenous, Capsule, Capsule - Oral, Solution - Parenteral, Injection, powder, lyophilized, for solution, Injection, emulsion - Intramuscular; Parenteral; Subcutaneous, Liquid - Intravenous, Kit, Kit - Oral, Injection, Injection - Intravenous, Solution / drops, Solution / drops - Oral

Warnings

Mephyton has one contraindication, so it must not be utilized when encountering the conditions in the following table.Mephyton Contraindications
Condition
Risk Level
Notes
Severe Hypersensitivity Reactions
Do Not Combine
Phylloquinone may interact with Pulse Frequency
There are 20 known major drug interactions with Mephyton.
Common Mephyton Drug Interactions
Drug Name
Risk Level
Description
(R)-warfarin
Major
The therapeutic efficacy of (R)-warfarin can be decreased when used in combination with Phylloquinone.
(S)-Warfarin
Major
The therapeutic efficacy of (S)-Warfarin can be decreased when used in combination with Phylloquinone.
4-hydroxycoumarin
Major
The therapeutic efficacy of 4-hydroxycoumarin can be decreased when used in combination with Phylloquinone.
Acenocoumarol
Major
The therapeutic efficacy of Acenocoumarol can be decreased when used in combination with Phylloquinone.
Clorindione
Major
The therapeutic efficacy of Clorindione can be decreased when used in combination with Phylloquinone.
Mephyton Toxicity & Overdose RiskTaking too much Vitamin K1 can be dangerous and can cause adverse reactions, particularly when administered intravenously. The toxic dose of Vitamin K1 in mice is 1170 mg/kg when administered intravenously, and more than 24180 mg/kg when taken orally. If someone has overdosed on Vitamin K1, they should receive appropriate care and treatment.

Mephyton Novel Uses: Which Conditions Have a Clinical Trial Featuring Mephyton?

100 active trials are currently in progress to assess the potential of Mephyton in alleviating Crohn Disease, Hemorrhagic Disease of the Newborn, and Obstructive Jaundice.
Condition
Clinical Trials
Trial Phases
Ulcerative Colitis
14 Actively Recruiting
Phase 3, Phase 2, Not Applicable, Phase 4, Phase 1
Jaundice, Obstructive
0 Actively Recruiting
Blood Coagulation Disorders
0 Actively Recruiting
Cystic Fibrosis
0 Actively Recruiting
Vitamin K Deficiency
0 Actively Recruiting
Vitamin supplementation
0 Actively Recruiting
Crohn Disease
0 Actively Recruiting
antibacterial therapy
0 Actively Recruiting
Hemorrhagic Disease of Newborn
0 Actively Recruiting
Celiac Disease
0 Actively Recruiting
Hypoprothrombinemias
0 Actively Recruiting
vitamin K
0 Actively Recruiting
hemorrhagic disease of the newborn
0 Actively Recruiting
Vitamin supplementation therapy
0 Actively Recruiting
long-acting anticoagulant rodenticides
0 Actively Recruiting
Celiac Disease
0 Actively Recruiting
Salicylate
0 Actively Recruiting
Anticoagulant Therapy
2 Actively Recruiting
Phase 4, Not Applicable
Intestinal resection
0 Actively Recruiting
Biliary Fistula
0 Actively Recruiting

Mephyton Reviews: What are patients saying about Mephyton?

3.3Patient Review
2/5/2009
Mephyton for Decreased Blood-Clotting from Low Vitamin K
This treatment helped me a lot, but I still experienced some side effects.
image of drug pills surrounding a glass of water symbolizing drug consumption

Patient Q&A Section about mephyton

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

What are the side effects of vitamin K injection?

"The following effects may occur at the injection site: pain, swelling, or soreness. You may also experience temporary flushing, taste changes, dizziness, rapid heartbeat, sweating, shortness of breath, or bluish lips/skin/nails. If any of these effects persist or worsen, tell your doctor or pharmacist promptly."

Answered by AI

Is phytonadione the generic name?

"Mephyton is a prescription drug used to treat various medical conditions. These include nutritional deficiencies, a low level of blood clotting factors, and reversing the effects of Warfarin. Mephyton may be used alone or in conjunction with other medications. It belongs to a class of drugs known as Hemostatics, which are vitamins that help promote blood clotting."

Answered by AI

What is Mephyton used for?

"Mephyton is used to prevent bleeding when blood clotting is impaired due to low levels of vitamin K or reduced activity of vitamin K."

Answered by AI

What is the generic name of vitamin K?

"Phytonadione is used to prevent bleeding in people who have blood clotting problems or too little vitamin K in their bodies. Phytonadione is a type of vitamin medication."

Answered by AI

Clinical Trials for Mephyton

Image of Victoria Hospital - London Health Sciences Centre in London, Canada.

Vitamin D for Inflammatory Bowel Disease

18 - 85
All Sexes
London, Canada
The aim of this clinical trial is to gain a better understanding of the effect of Vitamin D supplementation on disease activity and overall health. The main questions it aims to answer are: 1. What proportion of IBD patients adhere to Vitamin D supplement recommendations over a 12-month period? 2. Is the ASK-12 Questionnaire valid in measuring adherence among IBD patients? 3. Does the severity of a patient's Crohn's disease effect overall adherence, over a 12-month period? 4. Does the severity of a patient's Ulcerative Colitis disease effect overall adherence, over a 12-month period? 5. Does Vitamin D supplementation affect the health-related Quality of Life for IBD patients? 6. Is 2,000 IU/Day an effective dose to sustain appropriate blood Vitamin D levels among previously Vitamin deficient IBD patients? Participants will: * Take 2000 IU of Vitamin D every day for the next 12 months * Complete 2 surveys, bloodwork and a fecal calprotectin test at the initial, visit, 6 month follow up and 12 month follow up
Phase 1
Waitlist Available
Victoria Hospital - London Health Sciences CentreTerry Ponich, MD
Image of Rubix LS in Lawrence, United States.

Mirikizumab for Inflammatory Bowel Disease

60 - 99
All Sexes
Lawrence, MA
This research study looks at how safe and effective a medicine called Mirikizumab is for treating older adults (aged 60 and above) who have moderate to severe Crohn's disease (CD) or ulcerative colitis (UC). These two conditions, known as inflammatory bowel diseases (IBD), cause inflammation (swelling and irritation) in the digestive tract. Older adults with these conditions often have other health issues and face increased risks and complications, making it challenging for them to use certain treatments. Mirikizumab is already approved by the FDA for adults with IBD, but there's limited information about how well it works specifically for older adults. This study aims to fill that gap by seeing if Mirikizumab can help these patients safely manage their condition. The study plans to enroll around 150 people from various locations across the United States. Everyone participating will receive Mirikizumab according to the standard, FDA-approved guidelines. The main goal is to see how many participants achieve clinical remission, meaning their symptoms significantly improve or disappear, after 24 weeks of treatment. Researchers will also look at whether this remission lasts up to 48 weeks, how well symptoms are controlled without steroids, how treatment affects indicators of inflammation (such as blood tests), and how the participants feel overall based on their own reports. The safety of Mirikizumab will also be closely monitored throughout the study by regularly checking for any side effects. This study hopes to provide clearer information to help older adults with IBD and their doctors make better treatment decisions, ultimately improving health outcomes and quality of life.
Phase 4
Waitlist Available
Rubix LSEli Lilly and Company
Have you considered Mephyton clinical trials? We made a collection of clinical trials featuring Mephyton, we think they might fit your search criteria.Go to Trials
Image of Carolina Digestive Diseases- Site Number : 8400013 in Greenville, United States.

SAR441566 for Ulcerative Colitis

18 - 75
All Sexes
Greenville, NC
This is a Phase 2, multinational, multicenter, randomized, double-blind, placebo-controlled, dose ranging study to evaluate the efficacy and safety of SAR441566 in adults with moderate-to-severe UC. The primary objective of this study is to assess efficacy of different doses of SAR441566 on clinical remission in participants with moderate-to-severe ulcerative colitis. This study will include a screening period of up to 28 days (+ 7 calendar days if needed) followed by the main study treatment period of 52 weeks which will be comprised of a double blind (DB) treatment period with 12 weeks of induction period followed by a maintenance period of 40 weeks and 2-week follow-up after end of treatment. Additionally, an Open Label (OL) period of up to 40 weeks will be offered to eligible participants. * The study duration will be up to 59 weeks. * The treatment duration will be up to 52 weeks in the DB arm and up to 40 weeks in the OL arm. * The number of visits will be 12 for the main study treatment period and 8 for the OL treatment period.
Phase 2
Recruiting
Carolina Digestive Diseases- Site Number : 8400013 (+28 Sites)Sanofi
Image of University of Chicago in Chicago, United States.

Therapy De-escalation for Ulcerative Colitis

18 - 75
All Sexes
Chicago, IL
The goal of this study is to better understand treatment strategies for people with ulcerative colitis (UC). Researchers will compare patients with UC in histologic remission (no evidence of inflammation or active disease on endoscopy and biopsies) who continue to take medical therapy to patients with UC who de-escalate (decrease or discontinue) medical therapy. Both treatment strategies are considered within regular medical practice. Researchers want to find out whether remission can be maintained after de-escalation of therapy. Participants will be: * either be randomly assigned to continue medical therapy or de-escalate medical therapy -OR- be assigned per the participant's preference * clinically managed according to regular medical care * asked to provide blood, stool (poop), and tissue samples for study purposes
Recruiting
Has No Placebo
University of ChicagoDavid T Rubin, MD
Image of University of Pennsylvania in Philadelphia, United States.

Self-Help Interventions for Crohn's Disease

18+
All Sexes
Philadelphia, PA
EMPOWER-IBD aims to identify behavioral interventions to strengthen patients' self-efficacy for self-management as a mechanism to reduce IBD-related disability. This multisite, randomized controlled trial with 16 arms will randomize adults with moderate-to-severe IBD-related disability to a combination of four multimodal behavioral interventions to test their clinical effectiveness in reducing IBD-related disability and improving self-efficacy. The interventions are four existing, publicly available disease-specific self-help resources offered at no cost to the participants: a book, smart app, help center, and peer mentor. Participants will complete online surveys and may engage in virtual focus groups. Participants may receive an honorarium (e-gift card) and/or be entered into a lottery for a giftcards post-survey completion and focus group participation.
Waitlist Available
Has No Placebo
University of Pennsylvania
Have you considered Mephyton clinical trials? We made a collection of clinical trials featuring Mephyton, we think they might fit your search criteria.Go to Trials
Have you considered Mephyton clinical trials? We made a collection of clinical trials featuring Mephyton, we think they might fit your search criteria.Go to Trials
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