Mephyton

Jaundice, Obstructive, long-acting anticoagulant rodenticides, Vitamin K deficiency + 17 more

Treatment

7 FDA approvals

20 Active Studies for Mephyton

Treatment for

Jaundice, Obstructive

What is Mephyton

PhylloquinoneThe Generic name of this drug

Treatment SummaryVitamin K1 (also known as phylloquinone or phytonadione) is a fat-soluble vitamin that helps the body form clotting factors II, VII, IX, and X. It is used to treat clotting disorders caused by a lack of vitamin K. This vitamin has been available since 1939 and was approved by the FDA before 1955.

Mephytonis the brand name

image of different drug pills on a surface

Mephyton Overview & Background

Brand Name

Generic Name

First FDA Approval

How many FDA approvals?

Mephyton

Phylloquinone

1955

65

Approved as Treatment by the FDA

Phylloquinone, also known as Mephyton, is approved by the FDA for 7 uses including Hemorrhagic Disease of Newborn and hemorrhagic disease of the newborn .

Hemorrhagic Disease of Newborn

hemorrhagic disease of the newborn

Hypoprothrombinemia

Salicylate

Jaundice, Obstructive

Used to treat Jaundice, Obstructive in combination with Taurocholic acid

antibacterial therapy

Fistula, Biliary

Used to treat Fistula, Biliary in combination with Taurocholic acid

Effectiveness

How Mephyton Affects PatientsPhylloquinone is a vitamin K used to treat problems with blood clotting due to a lack of or reduced activity of vitamin K. It stays in the body for a long time and is safe to take in large doses. People taking this medication should have their prothrombin time monitored, and healthcare professionals should be aware of the risk of allergic reactions with injections.

How Mephyton works in the bodyVitamin K helps the body form blood clots by helping clotting proteins bind to calcium ions. This allows them to become active and be released into the blood, which helps stop bleeding. Vitamin K might also help prevent joint calcification, increased bone density, and reducing the risk of vascular calcification. These benefits are still being studied.

When to interrupt dosage

The suggested portion of Mephyton is contingent upon the diagnosed condition, like Sprue, Vitamin supplementation and Ulcerative Colitis. The measure of dosage is contingent upon the method of delivery outlined in the table beneath.

Condition

Dosage

Administration

Vitamin supplementation therapy

, 5.0 mg, 10.0 mg/mL, 2.0 mg/mL, 1.0 mg, 0.2 mg/mL, 0.015 mg/mL, 0.15 mg/mL, 0.2 mg, 0.02 mg, 0.08 mg, 0.15 mg, 0.02 mg/mL, 0.1 mg/mL

, Oral, Tablet, Tablet - Oral, Parenteral, Injection, emulsion, Injection, emulsion - Parenteral, Intramuscular; Parenteral; Subcutaneous, Injection, solution, Intramuscular; Intravenous; Subcutaneous, Injection, solution - Intramuscular; Intravenous; Subcutaneous, Injection, emulsion - Intramuscular; Intravenous; Subcutaneous, Solution, Solution - Intramuscular; Intravenous; Subcutaneous, Emulsion, Emulsion - Intramuscular; Intravenous; Subcutaneous, Intramuscular, Liquid - Intramuscular, Liquid, Intravenous, Injection, powder, lyophilized, for solution - Intravenous, Injection, solution - Intravenous, Capsule, Capsule - Oral, Solution - Parenteral, Injection, powder, lyophilized, for solution, Injection, emulsion - Intramuscular; Parenteral; Subcutaneous, Liquid - Intravenous, Kit, Kit - Oral, Injection, Injection - Intravenous, Solution / drops, Solution / drops - Oral

Gluten-Sensitive Enteropathy

, 5.0 mg, 10.0 mg/mL, 2.0 mg/mL, 1.0 mg, 0.2 mg/mL, 0.015 mg/mL, 0.15 mg/mL, 0.2 mg, 0.02 mg, 0.08 mg, 0.15 mg, 0.02 mg/mL, 0.1 mg/mL

, Oral, Tablet, Tablet - Oral, Parenteral, Injection, emulsion, Injection, emulsion - Parenteral, Intramuscular; Parenteral; Subcutaneous, Injection, solution, Intramuscular; Intravenous; Subcutaneous, Injection, solution - Intramuscular; Intravenous; Subcutaneous, Injection, emulsion - Intramuscular; Intravenous; Subcutaneous, Solution, Solution - Intramuscular; Intravenous; Subcutaneous, Emulsion, Emulsion - Intramuscular; Intravenous; Subcutaneous, Intramuscular, Liquid - Intramuscular, Liquid, Intravenous, Injection, powder, lyophilized, for solution - Intravenous, Injection, solution - Intravenous, Capsule, Capsule - Oral, Solution - Parenteral, Injection, powder, lyophilized, for solution, Injection, emulsion - Intramuscular; Parenteral; Subcutaneous, Liquid - Intravenous, Kit, Kit - Oral, Injection, Injection - Intravenous, Solution / drops, Solution / drops - Oral

Hypoprothrombinemia

, 5.0 mg, 10.0 mg/mL, 2.0 mg/mL, 1.0 mg, 0.2 mg/mL, 0.015 mg/mL, 0.15 mg/mL, 0.2 mg, 0.02 mg, 0.08 mg, 0.15 mg, 0.02 mg/mL, 0.1 mg/mL

, Oral, Tablet, Tablet - Oral, Parenteral, Injection, emulsion, Injection, emulsion - Parenteral, Intramuscular; Parenteral; Subcutaneous, Injection, solution, Intramuscular; Intravenous; Subcutaneous, Injection, solution - Intramuscular; Intravenous; Subcutaneous, Injection, emulsion - Intramuscular; Intravenous; Subcutaneous, Solution, Solution - Intramuscular; Intravenous; Subcutaneous, Emulsion, Emulsion - Intramuscular; Intravenous; Subcutaneous, Intramuscular, Liquid - Intramuscular, Liquid, Intravenous, Injection, powder, lyophilized, for solution - Intravenous, Injection, solution - Intravenous, Capsule, Capsule - Oral, Solution - Parenteral, Injection, powder, lyophilized, for solution, Injection, emulsion - Intramuscular; Parenteral; Subcutaneous, Liquid - Intravenous, Kit, Kit - Oral, Injection, Injection - Intravenous, Solution / drops, Solution / drops - Oral

Anticoagulant Therapy

, 5.0 mg, 10.0 mg/mL, 2.0 mg/mL, 1.0 mg, 0.2 mg/mL, 0.015 mg/mL, 0.15 mg/mL, 0.2 mg, 0.02 mg, 0.08 mg, 0.15 mg, 0.02 mg/mL, 0.1 mg/mL

, Oral, Tablet, Tablet - Oral, Parenteral, Injection, emulsion, Injection, emulsion - Parenteral, Intramuscular; Parenteral; Subcutaneous, Injection, solution, Intramuscular; Intravenous; Subcutaneous, Injection, solution - Intramuscular; Intravenous; Subcutaneous, Injection, emulsion - Intramuscular; Intravenous; Subcutaneous, Solution, Solution - Intramuscular; Intravenous; Subcutaneous, Emulsion, Emulsion - Intramuscular; Intravenous; Subcutaneous, Intramuscular, Liquid - Intramuscular, Liquid, Intravenous, Injection, powder, lyophilized, for solution - Intravenous, Injection, solution - Intravenous, Capsule, Capsule - Oral, Solution - Parenteral, Injection, powder, lyophilized, for solution, Injection, emulsion - Intramuscular; Parenteral; Subcutaneous, Liquid - Intravenous, Kit, Kit - Oral, Injection, Injection - Intravenous, Solution / drops, Solution / drops - Oral

Pancreatic Cystic Fibrosis

, 5.0 mg, 10.0 mg/mL, 2.0 mg/mL, 1.0 mg, 0.2 mg/mL, 0.015 mg/mL, 0.15 mg/mL, 0.2 mg, 0.02 mg, 0.08 mg, 0.15 mg, 0.02 mg/mL, 0.1 mg/mL

, Oral, Tablet, Tablet - Oral, Parenteral, Injection, emulsion, Injection, emulsion - Parenteral, Intramuscular; Parenteral; Subcutaneous, Injection, solution, Intramuscular; Intravenous; Subcutaneous, Injection, solution - Intramuscular; Intravenous; Subcutaneous, Injection, emulsion - Intramuscular; Intravenous; Subcutaneous, Solution, Solution - Intramuscular; Intravenous; Subcutaneous, Emulsion, Emulsion - Intramuscular; Intravenous; Subcutaneous, Intramuscular, Liquid - Intramuscular, Liquid, Intravenous, Injection, powder, lyophilized, for solution - Intravenous, Injection, solution - Intravenous, Capsule, Capsule - Oral, Solution - Parenteral, Injection, powder, lyophilized, for solution, Injection, emulsion - Intramuscular; Parenteral; Subcutaneous, Liquid - Intravenous, Kit, Kit - Oral, Injection, Injection - Intravenous, Solution / drops, Solution / drops - Oral

Crohn Disease

, 5.0 mg, 10.0 mg/mL, 2.0 mg/mL, 1.0 mg, 0.2 mg/mL, 0.015 mg/mL, 0.15 mg/mL, 0.2 mg, 0.02 mg, 0.08 mg, 0.15 mg, 0.02 mg/mL, 0.1 mg/mL

, Oral, Tablet, Tablet - Oral, Parenteral, Injection, emulsion, Injection, emulsion - Parenteral, Intramuscular; Parenteral; Subcutaneous, Injection, solution, Intramuscular; Intravenous; Subcutaneous, Injection, solution - Intramuscular; Intravenous; Subcutaneous, Injection, emulsion - Intramuscular; Intravenous; Subcutaneous, Solution, Solution - Intramuscular; Intravenous; Subcutaneous, Emulsion, Emulsion - Intramuscular; Intravenous; Subcutaneous, Intramuscular, Liquid - Intramuscular, Liquid, Intravenous, Injection, powder, lyophilized, for solution - Intravenous, Injection, solution - Intravenous, Capsule, Capsule - Oral, Solution - Parenteral, Injection, powder, lyophilized, for solution, Injection, emulsion - Intramuscular; Parenteral; Subcutaneous, Liquid - Intravenous, Kit, Kit - Oral, Injection, Injection - Intravenous, Solution / drops, Solution / drops - Oral

Vitamin supplementation

, 5.0 mg, 10.0 mg/mL, 2.0 mg/mL, 1.0 mg, 0.2 mg/mL, 0.015 mg/mL, 0.15 mg/mL, 0.2 mg, 0.02 mg, 0.08 mg, 0.15 mg, 0.02 mg/mL, 0.1 mg/mL

, Oral, Tablet, Tablet - Oral, Parenteral, Injection, emulsion, Injection, emulsion - Parenteral, Intramuscular; Parenteral; Subcutaneous, Injection, solution, Intramuscular; Intravenous; Subcutaneous, Injection, solution - Intramuscular; Intravenous; Subcutaneous, Injection, emulsion - Intramuscular; Intravenous; Subcutaneous, Solution, Solution - Intramuscular; Intravenous; Subcutaneous, Emulsion, Emulsion - Intramuscular; Intravenous; Subcutaneous, Intramuscular, Liquid - Intramuscular, Liquid, Intravenous, Injection, powder, lyophilized, for solution - Intravenous, Injection, solution - Intravenous, Capsule, Capsule - Oral, Solution - Parenteral, Injection, powder, lyophilized, for solution, Injection, emulsion - Intramuscular; Parenteral; Subcutaneous, Liquid - Intravenous, Kit, Kit - Oral, Injection, Injection - Intravenous, Solution / drops, Solution / drops - Oral

Fistula, Biliary

, 5.0 mg, 10.0 mg/mL, 2.0 mg/mL, 1.0 mg, 0.2 mg/mL, 0.015 mg/mL, 0.15 mg/mL, 0.2 mg, 0.02 mg, 0.08 mg, 0.15 mg, 0.02 mg/mL, 0.1 mg/mL

, Oral, Tablet, Tablet - Oral, Parenteral, Injection, emulsion, Injection, emulsion - Parenteral, Intramuscular; Parenteral; Subcutaneous, Injection, solution, Intramuscular; Intravenous; Subcutaneous, Injection, solution - Intramuscular; Intravenous; Subcutaneous, Injection, emulsion - Intramuscular; Intravenous; Subcutaneous, Solution, Solution - Intramuscular; Intravenous; Subcutaneous, Emulsion, Emulsion - Intramuscular; Intravenous; Subcutaneous, Intramuscular, Liquid - Intramuscular, Liquid, Intravenous, Injection, powder, lyophilized, for solution - Intravenous, Injection, solution - Intravenous, Capsule, Capsule - Oral, Solution - Parenteral, Injection, powder, lyophilized, for solution, Injection, emulsion - Intramuscular; Parenteral; Subcutaneous, Liquid - Intravenous, Kit, Kit - Oral, Injection, Injection - Intravenous, Solution / drops, Solution / drops - Oral

Intestinal resection

, 5.0 mg, 10.0 mg/mL, 2.0 mg/mL, 1.0 mg, 0.2 mg/mL, 0.015 mg/mL, 0.15 mg/mL, 0.2 mg, 0.02 mg, 0.08 mg, 0.15 mg, 0.02 mg/mL, 0.1 mg/mL

, Oral, Tablet, Tablet - Oral, Parenteral, Injection, emulsion, Injection, emulsion - Parenteral, Intramuscular; Parenteral; Subcutaneous, Injection, solution, Intramuscular; Intravenous; Subcutaneous, Injection, solution - Intramuscular; Intravenous; Subcutaneous, Injection, emulsion - Intramuscular; Intravenous; Subcutaneous, Solution, Solution - Intramuscular; Intravenous; Subcutaneous, Emulsion, Emulsion - Intramuscular; Intravenous; Subcutaneous, Intramuscular, Liquid - Intramuscular, Liquid, Intravenous, Injection, powder, lyophilized, for solution - Intravenous, Injection, solution - Intravenous, Capsule, Capsule - Oral, Solution - Parenteral, Injection, powder, lyophilized, for solution, Injection, emulsion - Intramuscular; Parenteral; Subcutaneous, Liquid - Intravenous, Kit, Kit - Oral, Injection, Injection - Intravenous, Solution / drops, Solution / drops - Oral

vitamin K

, 5.0 mg, 10.0 mg/mL, 2.0 mg/mL, 1.0 mg, 0.2 mg/mL, 0.015 mg/mL, 0.15 mg/mL, 0.2 mg, 0.02 mg, 0.08 mg, 0.15 mg, 0.02 mg/mL, 0.1 mg/mL

, Oral, Tablet, Tablet - Oral, Parenteral, Injection, emulsion, Injection, emulsion - Parenteral, Intramuscular; Parenteral; Subcutaneous, Injection, solution, Intramuscular; Intravenous; Subcutaneous, Injection, solution - Intramuscular; Intravenous; Subcutaneous, Injection, emulsion - Intramuscular; Intravenous; Subcutaneous, Solution, Solution - Intramuscular; Intravenous; Subcutaneous, Emulsion, Emulsion - Intramuscular; Intravenous; Subcutaneous, Intramuscular, Liquid - Intramuscular, Liquid, Intravenous, Injection, powder, lyophilized, for solution - Intravenous, Injection, solution - Intravenous, Capsule, Capsule - Oral, Solution - Parenteral, Injection, powder, lyophilized, for solution, Injection, emulsion - Intramuscular; Parenteral; Subcutaneous, Liquid - Intravenous, Kit, Kit - Oral, Injection, Injection - Intravenous, Solution / drops, Solution / drops - Oral

Hemorrhagic Disease of Newborn

, 5.0 mg, 10.0 mg/mL, 2.0 mg/mL, 1.0 mg, 0.2 mg/mL, 0.015 mg/mL, 0.15 mg/mL, 0.2 mg, 0.02 mg, 0.08 mg, 0.15 mg, 0.02 mg/mL, 0.1 mg/mL

, Oral, Tablet, Tablet - Oral, Parenteral, Injection, emulsion, Injection, emulsion - Parenteral, Intramuscular; Parenteral; Subcutaneous, Injection, solution, Intramuscular; Intravenous; Subcutaneous, Injection, solution - Intramuscular; Intravenous; Subcutaneous, Injection, emulsion - Intramuscular; Intravenous; Subcutaneous, Solution, Solution - Intramuscular; Intravenous; Subcutaneous, Emulsion, Emulsion - Intramuscular; Intravenous; Subcutaneous, Intramuscular, Liquid - Intramuscular, Liquid, Intravenous, Injection, powder, lyophilized, for solution - Intravenous, Injection, solution - Intravenous, Capsule, Capsule - Oral, Solution - Parenteral, Injection, powder, lyophilized, for solution, Injection, emulsion - Intramuscular; Parenteral; Subcutaneous, Liquid - Intravenous, Kit, Kit - Oral, Injection, Injection - Intravenous, Solution / drops, Solution / drops - Oral

Salicylate

, 5.0 mg, 10.0 mg/mL, 2.0 mg/mL, 1.0 mg, 0.2 mg/mL, 0.015 mg/mL, 0.15 mg/mL, 0.2 mg, 0.02 mg, 0.08 mg, 0.15 mg, 0.02 mg/mL, 0.1 mg/mL

, Oral, Tablet, Tablet - Oral, Parenteral, Injection, emulsion, Injection, emulsion - Parenteral, Intramuscular; Parenteral; Subcutaneous, Injection, solution, Intramuscular; Intravenous; Subcutaneous, Injection, solution - Intramuscular; Intravenous; Subcutaneous, Injection, emulsion - Intramuscular; Intravenous; Subcutaneous, Solution, Solution - Intramuscular; Intravenous; Subcutaneous, Emulsion, Emulsion - Intramuscular; Intravenous; Subcutaneous, Intramuscular, Liquid - Intramuscular, Liquid, Intravenous, Injection, powder, lyophilized, for solution - Intravenous, Injection, solution - Intravenous, Capsule, Capsule - Oral, Solution - Parenteral, Injection, powder, lyophilized, for solution, Injection, emulsion - Intramuscular; Parenteral; Subcutaneous, Liquid - Intravenous, Kit, Kit - Oral, Injection, Injection - Intravenous, Solution / drops, Solution / drops - Oral

Sprue

, 5.0 mg, 10.0 mg/mL, 2.0 mg/mL, 1.0 mg, 0.2 mg/mL, 0.015 mg/mL, 0.15 mg/mL, 0.2 mg, 0.02 mg, 0.08 mg, 0.15 mg, 0.02 mg/mL, 0.1 mg/mL

, Oral, Tablet, Tablet - Oral, Parenteral, Injection, emulsion, Injection, emulsion - Parenteral, Intramuscular; Parenteral; Subcutaneous, Injection, solution, Intramuscular; Intravenous; Subcutaneous, Injection, solution - Intramuscular; Intravenous; Subcutaneous, Injection, emulsion - Intramuscular; Intravenous; Subcutaneous, Solution, Solution - Intramuscular; Intravenous; Subcutaneous, Emulsion, Emulsion - Intramuscular; Intravenous; Subcutaneous, Intramuscular, Liquid - Intramuscular, Liquid, Intravenous, Injection, powder, lyophilized, for solution - Intravenous, Injection, solution - Intravenous, Capsule, Capsule - Oral, Solution - Parenteral, Injection, powder, lyophilized, for solution, Injection, emulsion - Intramuscular; Parenteral; Subcutaneous, Liquid - Intravenous, Kit, Kit - Oral, Injection, Injection - Intravenous, Solution / drops, Solution / drops - Oral

Jaundice, Obstructive

, 5.0 mg, 10.0 mg/mL, 2.0 mg/mL, 1.0 mg, 0.2 mg/mL, 0.015 mg/mL, 0.15 mg/mL, 0.2 mg, 0.02 mg, 0.08 mg, 0.15 mg, 0.02 mg/mL, 0.1 mg/mL

, Oral, Tablet, Tablet - Oral, Parenteral, Injection, emulsion, Injection, emulsion - Parenteral, Intramuscular; Parenteral; Subcutaneous, Injection, solution, Intramuscular; Intravenous; Subcutaneous, Injection, solution - Intramuscular; Intravenous; Subcutaneous, Injection, emulsion - Intramuscular; Intravenous; Subcutaneous, Solution, Solution - Intramuscular; Intravenous; Subcutaneous, Emulsion, Emulsion - Intramuscular; Intravenous; Subcutaneous, Intramuscular, Liquid - Intramuscular, Liquid, Intravenous, Injection, powder, lyophilized, for solution - Intravenous, Injection, solution - Intravenous, Capsule, Capsule - Oral, Solution - Parenteral, Injection, powder, lyophilized, for solution, Injection, emulsion - Intramuscular; Parenteral; Subcutaneous, Liquid - Intravenous, Kit, Kit - Oral, Injection, Injection - Intravenous, Solution / drops, Solution / drops - Oral

Vitamin K deficiency

, 5.0 mg, 10.0 mg/mL, 2.0 mg/mL, 1.0 mg, 0.2 mg/mL, 0.015 mg/mL, 0.15 mg/mL, 0.2 mg, 0.02 mg, 0.08 mg, 0.15 mg, 0.02 mg/mL, 0.1 mg/mL

, Oral, Tablet, Tablet - Oral, Parenteral, Injection, emulsion, Injection, emulsion - Parenteral, Intramuscular; Parenteral; Subcutaneous, Injection, solution, Intramuscular; Intravenous; Subcutaneous, Injection, solution - Intramuscular; Intravenous; Subcutaneous, Injection, emulsion - Intramuscular; Intravenous; Subcutaneous, Solution, Solution - Intramuscular; Intravenous; Subcutaneous, Emulsion, Emulsion - Intramuscular; Intravenous; Subcutaneous, Intramuscular, Liquid - Intramuscular, Liquid, Intravenous, Injection, powder, lyophilized, for solution - Intravenous, Injection, solution - Intravenous, Capsule, Capsule - Oral, Solution - Parenteral, Injection, powder, lyophilized, for solution, Injection, emulsion - Intramuscular; Parenteral; Subcutaneous, Liquid - Intravenous, Kit, Kit - Oral, Injection, Injection - Intravenous, Solution / drops, Solution / drops - Oral

long-acting anticoagulant rodenticides

, 5.0 mg, 10.0 mg/mL, 2.0 mg/mL, 1.0 mg, 0.2 mg/mL, 0.015 mg/mL, 0.15 mg/mL, 0.2 mg, 0.02 mg, 0.08 mg, 0.15 mg, 0.02 mg/mL, 0.1 mg/mL

, Oral, Tablet, Tablet - Oral, Parenteral, Injection, emulsion, Injection, emulsion - Parenteral, Intramuscular; Parenteral; Subcutaneous, Injection, solution, Intramuscular; Intravenous; Subcutaneous, Injection, solution - Intramuscular; Intravenous; Subcutaneous, Injection, emulsion - Intramuscular; Intravenous; Subcutaneous, Solution, Solution - Intramuscular; Intravenous; Subcutaneous, Emulsion, Emulsion - Intramuscular; Intravenous; Subcutaneous, Intramuscular, Liquid - Intramuscular, Liquid, Intravenous, Injection, powder, lyophilized, for solution - Intravenous, Injection, solution - Intravenous, Capsule, Capsule - Oral, Solution - Parenteral, Injection, powder, lyophilized, for solution, Injection, emulsion - Intramuscular; Parenteral; Subcutaneous, Liquid - Intravenous, Kit, Kit - Oral, Injection, Injection - Intravenous, Solution / drops, Solution / drops - Oral

hemorrhagic disease of the newborn

, 5.0 mg, 10.0 mg/mL, 2.0 mg/mL, 1.0 mg, 0.2 mg/mL, 0.015 mg/mL, 0.15 mg/mL, 0.2 mg, 0.02 mg, 0.08 mg, 0.15 mg, 0.02 mg/mL, 0.1 mg/mL

, Oral, Tablet, Tablet - Oral, Parenteral, Injection, emulsion, Injection, emulsion - Parenteral, Intramuscular; Parenteral; Subcutaneous, Injection, solution, Intramuscular; Intravenous; Subcutaneous, Injection, solution - Intramuscular; Intravenous; Subcutaneous, Injection, emulsion - Intramuscular; Intravenous; Subcutaneous, Solution, Solution - Intramuscular; Intravenous; Subcutaneous, Emulsion, Emulsion - Intramuscular; Intravenous; Subcutaneous, Intramuscular, Liquid - Intramuscular, Liquid, Intravenous, Injection, powder, lyophilized, for solution - Intravenous, Injection, solution - Intravenous, Capsule, Capsule - Oral, Solution - Parenteral, Injection, powder, lyophilized, for solution, Injection, emulsion - Intramuscular; Parenteral; Subcutaneous, Liquid - Intravenous, Kit, Kit - Oral, Injection, Injection - Intravenous, Solution / drops, Solution / drops - Oral

antibacterial therapy

, 5.0 mg, 10.0 mg/mL, 2.0 mg/mL, 1.0 mg, 0.2 mg/mL, 0.015 mg/mL, 0.15 mg/mL, 0.2 mg, 0.02 mg, 0.08 mg, 0.15 mg, 0.02 mg/mL, 0.1 mg/mL

, Oral, Tablet, Tablet - Oral, Parenteral, Injection, emulsion, Injection, emulsion - Parenteral, Intramuscular; Parenteral; Subcutaneous, Injection, solution, Intramuscular; Intravenous; Subcutaneous, Injection, solution - Intramuscular; Intravenous; Subcutaneous, Injection, emulsion - Intramuscular; Intravenous; Subcutaneous, Solution, Solution - Intramuscular; Intravenous; Subcutaneous, Emulsion, Emulsion - Intramuscular; Intravenous; Subcutaneous, Intramuscular, Liquid - Intramuscular, Liquid, Intravenous, Injection, powder, lyophilized, for solution - Intravenous, Injection, solution - Intravenous, Capsule, Capsule - Oral, Solution - Parenteral, Injection, powder, lyophilized, for solution, Injection, emulsion - Intramuscular; Parenteral; Subcutaneous, Liquid - Intravenous, Kit, Kit - Oral, Injection, Injection - Intravenous, Solution / drops, Solution / drops - Oral

Ulcerative Colitis

, 5.0 mg, 10.0 mg/mL, 2.0 mg/mL, 1.0 mg, 0.2 mg/mL, 0.015 mg/mL, 0.15 mg/mL, 0.2 mg, 0.02 mg, 0.08 mg, 0.15 mg, 0.02 mg/mL, 0.1 mg/mL

, Oral, Tablet, Tablet - Oral, Parenteral, Injection, emulsion, Injection, emulsion - Parenteral, Intramuscular; Parenteral; Subcutaneous, Injection, solution, Intramuscular; Intravenous; Subcutaneous, Injection, solution - Intramuscular; Intravenous; Subcutaneous, Injection, emulsion - Intramuscular; Intravenous; Subcutaneous, Solution, Solution - Intramuscular; Intravenous; Subcutaneous, Emulsion, Emulsion - Intramuscular; Intravenous; Subcutaneous, Intramuscular, Liquid - Intramuscular, Liquid, Intravenous, Injection, powder, lyophilized, for solution - Intravenous, Injection, solution - Intravenous, Capsule, Capsule - Oral, Solution - Parenteral, Injection, powder, lyophilized, for solution, Injection, emulsion - Intramuscular; Parenteral; Subcutaneous, Liquid - Intravenous, Kit, Kit - Oral, Injection, Injection - Intravenous, Solution / drops, Solution / drops - Oral

Coagulation Disorder

, 5.0 mg, 10.0 mg/mL, 2.0 mg/mL, 1.0 mg, 0.2 mg/mL, 0.015 mg/mL, 0.15 mg/mL, 0.2 mg, 0.02 mg, 0.08 mg, 0.15 mg, 0.02 mg/mL, 0.1 mg/mL

, Oral, Tablet, Tablet - Oral, Parenteral, Injection, emulsion, Injection, emulsion - Parenteral, Intramuscular; Parenteral; Subcutaneous, Injection, solution, Intramuscular; Intravenous; Subcutaneous, Injection, solution - Intramuscular; Intravenous; Subcutaneous, Injection, emulsion - Intramuscular; Intravenous; Subcutaneous, Solution, Solution - Intramuscular; Intravenous; Subcutaneous, Emulsion, Emulsion - Intramuscular; Intravenous; Subcutaneous, Intramuscular, Liquid - Intramuscular, Liquid, Intravenous, Injection, powder, lyophilized, for solution - Intravenous, Injection, solution - Intravenous, Capsule, Capsule - Oral, Solution - Parenteral, Injection, powder, lyophilized, for solution, Injection, emulsion - Intramuscular; Parenteral; Subcutaneous, Liquid - Intravenous, Kit, Kit - Oral, Injection, Injection - Intravenous, Solution / drops, Solution / drops - Oral

Warnings

Mephyton has one contraindication, so it must not be utilized when encountering the conditions in the following table.Mephyton Contraindications

Condition

Risk Level

Notes

Severe Hypersensitivity Reactions

Do Not Combine

Phylloquinone may interact with Pulse Frequency

There are 20 known major drug interactions with Mephyton.

Common Mephyton Drug Interactions

Drug Name

Risk Level

Description

(R)-warfarin

Major

The therapeutic efficacy of (R)-warfarin can be decreased when used in combination with Phylloquinone.

(S)-Warfarin

Major

The therapeutic efficacy of (S)-Warfarin can be decreased when used in combination with Phylloquinone.

4-hydroxycoumarin

Major

The therapeutic efficacy of 4-hydroxycoumarin can be decreased when used in combination with Phylloquinone.

Acenocoumarol

Major

The therapeutic efficacy of Acenocoumarol can be decreased when used in combination with Phylloquinone.

Clorindione

Major

The therapeutic efficacy of Clorindione can be decreased when used in combination with Phylloquinone.

Mephyton Toxicity & Overdose RiskTaking too much Vitamin K1 can be dangerous and can cause adverse reactions, particularly when administered intravenously. The toxic dose of Vitamin K1 in mice is 1170 mg/kg when administered intravenously, and more than 24180 mg/kg when taken orally. If someone has overdosed on Vitamin K1, they should receive appropriate care and treatment.

Mephyton Novel Uses: Which Conditions Have a Clinical Trial Featuring Mephyton?

100 active trials are currently in progress to assess the potential of Mephyton in alleviating Crohn Disease, Hemorrhagic Disease of the Newborn, and Obstructive Jaundice.

Condition

Clinical Trials

Trial Phases

Ulcerative Colitis

93 Actively Recruiting

Phase 2, Not Applicable, Phase 3, Phase 1, Early Phase 1, Phase 4

Vitamin K deficiency

0 Actively Recruiting

Pancreatic Cystic Fibrosis

0 Actively Recruiting

Vitamin supplementation

0 Actively Recruiting

Crohn Disease

0 Actively Recruiting

antibacterial therapy

0 Actively Recruiting

Hemorrhagic Disease of Newborn

0 Actively Recruiting

Sprue

0 Actively Recruiting

Hypoprothrombinemia

0 Actively Recruiting

vitamin K

0 Actively Recruiting

hemorrhagic disease of the newborn

0 Actively Recruiting

Vitamin supplementation therapy

0 Actively Recruiting

long-acting anticoagulant rodenticides

0 Actively Recruiting

Gluten-Sensitive Enteropathy

0 Actively Recruiting

Jaundice, Obstructive

0 Actively Recruiting

Coagulation Disorder

3 Actively Recruiting

Phase 3, Not Applicable, Phase 1

Salicylate

0 Actively Recruiting

Anticoagulant Therapy

0 Actively Recruiting

Intestinal resection

0 Actively Recruiting

Fistula, Biliary

0 Actively Recruiting

Mephyton Reviews: What are patients saying about Mephyton?

3.3Patient Review

2/5/2009

Mephyton for Decreased Blood-Clotting from Low Vitamin K

This treatment helped me a lot, but I still experienced some side effects.

image of drug pills surrounding a glass of water symbolizing drug consumption

Patient Q&A Section about mephyton

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

What are the side effects of vitamin K injection?

"The following effects may occur at the injection site: pain, swelling, or soreness. You may also experience temporary flushing, taste changes, dizziness, rapid heartbeat, sweating, shortness of breath, or bluish lips/skin/nails. If any of these effects persist or worsen, tell your doctor or pharmacist promptly."

Answered by AI

Is phytonadione the generic name?

"Mephyton is a prescription drug used to treat various medical conditions. These include nutritional deficiencies, a low level of blood clotting factors, and reversing the effects of Warfarin. Mephyton may be used alone or in conjunction with other medications. It belongs to a class of drugs known as Hemostatics, which are vitamins that help promote blood clotting."

Answered by AI

What is Mephyton used for?

"Mephyton is used to prevent bleeding when blood clotting is impaired due to low levels of vitamin K or reduced activity of vitamin K."

Answered by AI

What is the generic name of vitamin K?

"Phytonadione is used to prevent bleeding in people who have blood clotting problems or too little vitamin K in their bodies. Phytonadione is a type of vitamin medication."

Answered by AI

Clinical Trials for Mephyton

Image of University of Chicago in Chicago, United States.

Digital Support for Inflammatory Bowel Disease

This trial aims to see if using a digital wellness app with artificial intelligence and virtual reality can provide mental health support to patients with inflammatory bowel disease and mild to moderate anxiety or depression. The study will assess

Waitlist Available

University of ChicagoDavid T Rubin, MD

Image of Montefiore Medical Center in Bronx, United States.

Digital Mind Body Intervention for Inflammatory Bowel Disease

This trial is looking at the relationship between psychological distress and inflammatory bowel disease (IBD). It found that psychological distress can worsen IBD symptoms and vice versa. Patients with both IBD and psychological

Waitlist Available

Montefiore Medical CenterRuby Greywoode, MD

Image of UCLA in Los Angeles, United States.

Prebiotics for Ulcerative Colitis

Los Angeles, CA

This trial aims to understand the effects of prebiotics on gut health in patients with inflammatory bowel disease (IBD). Participants will be given prebiotic supplements for 8 weeks and their dietary habits

Image of University of California San Diego in San Diego, United States.

Digital Care for Inflammatory Bowel Disease

This trial aims to see if patients with Inflammatory Bowel Disease (IBD) have better outcomes and feel more empowered if they can communicate with their clinical team through text messages and have their symptoms monitored

University of California San Diego (+7 Sites)Michael D Kappelman, MD, MPH

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Image of Brigham and Women's Hospital in Chestnut Hill, United States.

BRS201 for Ulcerative Colitis

Chestnut Hill, MA

This trial is testing a new drug called BRS201 to see if it can help patients with mild ulcerative colitis. Participants will take the drug and a placebo for 4 weeks each in a

Waitlist Available

Brigham and Women's Hospital

Image of Mayo Clinic in Rochester, United States.

Intestinal Ultrasound for Pouchitis

This trial investigates the use of intestinal ultrasound (IUS) in evaluating inflammatory bowel disease (IBD), specifically ulcerative colitis (UC) patients with an ileal pouch-anal anastom

Mayo ClinicDarrell Pardi, MD

Image of Center for Cancer and Blood Disorders in Bethesda, United States.

HMPL-523 for Low Platelet Count

"This trial will test the safety, side effects, and effectiveness of HMPL-523 in adults with ITP at multiple locations with full transparency about the treatment being administered."

Center for Cancer and Blood Disorders (+9 Sites)William Schelman, MD, PhDHutchmed

Image of VVCRD Research in Garden Grove, United States.

GS-1427 for Ulcerative Colitis

Garden Grove, CA

"This trial is testing a new drug, GS-1427, to see if it is safe and effective in treating people with moderate to severe ulcerative colitis. The study will compare different groups of

VVCRD Research (+25 Sites)Gilead Study DirectorGilead Sciences

Have you considered Mephyton clinical trials? We made a collection of clinical trials featuring Mephyton, we think they might fit your search criteria.

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Image of Atlantic Medical Research /ID# 258507 in Margate, United States.

Lutikizumab for Ulcerative Colitis

"This trial is testing a new drug called lutikizumab for treating ulcerative colitis (UC) by comparing it to an existing drug called adalimumab. Participants will be divided into

Atlantic Medical Research /ID# 258507 (+27 Sites)ABBVIE INC.AbbVie

Image of GastroIntestinal BioSciences in Los Angeles, United States.

TAK-279 for Ulcerative Colitis

Los Angeles, CA

This trial aims to see if TAK-279 can reduce bowel inflammation and symptoms compared to a placebo. Participants will take TAK-279 or placebo capsules for 3 months and then all participants will

GastroIntestinal BioSciences (+23 Sites)Study DirectorTakeda

Image of Tyler Research Institute, LLC in Tyler, United States.

Vixarelimab for Ulcerative Colitis

This trial is testing a new medication called vixarelimab to help people with moderate to severe Ulcerative Colitis who haven't had success with other treatments. The study will check if the medication can reduce symptoms and help patients feel better over time.

Tyler Research Institute, LLC (+1 Sites)Clinical TrialGenentech, Inc.

Image of AnaptysBio Investigative Site 10-101 in Kissimmee, United States.

Rosnilimab for Ulcerative Colitis

This trial is testing a new medication called Rosnilimab to see if it can help people with moderate to severe ulcerative colitis. The study will check if the medication is safe and if it works well to reduce inflammation in the colon. Researchers want to find out if Rosnilimab can improve symptoms for those who haven't had success with other treatments.

AnaptysBio Investigative Site 10-101 (+22 Sites)Zurab Machaidze, MDAnaptysBio, Inc.

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