Metoprolol Tartrate

Atrial Fibrillation, Thyroid Crisis, Migraine + 9 more

Treatment

4 FDA approvals

20 Active Studies for Metoprolol Tartrate

What is Metoprolol Tartrate

Metoprolol

The Generic name of this drug

Treatment Summary

Metoprolol is a medication used to block the effects of certain hormones in the body. It is available in both an immediate-release and extended-release form and can be used to treat high blood pressure, heart failure, and angina. Metoprolol was developed in 1969 and approved by the FDA in 1978. It is widely prescribed around the world and is one of the preferred treatments for heart-related conditions.

Lopressor

is the brand name

image of different drug pills on a surface

Metoprolol Tartrate Overview & Background

Brand Name

Generic Name

First FDA Approval

How many FDA approvals?

Lopressor

Metoprolol

1978

983

Approved as Treatment by the FDA

Metoprolol, also known as Lopressor, is approved by the FDA for 4 uses including Hypertensive disease and Hypertension .

Hypertensive disease

Used to treat High Blood Pressure (Hypertension) in combination with Hydrochlorothiazide

Hypertension

Used to treat nonresponsive to antihypertensive monotherapy in combination with Hydrochlorothiazide

Hemodynamically Stable

Heart Attack

Effectiveness

How Metoprolol Tartrate Affects Patients

When used correctly, metoprolol can help slow down the heart rate and reduce the amount of oxygen the heart needs to function. It has also been used to treat arrhythmia and has been found to reduce sudden cardiac death and heart attack in individuals who have had a heart attack. In clinical trials performed in 1990, taking metoprolol long-term after a heart attack reduced mortality and re-infarction by 17%.

How Metoprolol Tartrate works in the body

Metoprolol is a medication that works to decrease the activity of certain receptors in the heart, resulting in a reduced heart rate and lower blood pressure. It does not affect other parts of the body, such as the nervous system or muscle cells.

When to interrupt dosage

The dose of Metoprolol Tartrate is contingent upon the determined illness, such as Hemodynamically Stable, Thyroid Crisis and Atrial Fibrillation. The volume of dosage shifts as per the method of delivery (e.g. Tablet, coated or Tablet - Oral) featured in the table beneath.

Condition

Dosage

Administration

Chest Pain

, 50.0 mg, 100.0 mg, 5.0 mg/mL, 25.0 mg, 200.0 mg, 0.5 mg, 0.25 mg, 1.0 mg/mL, 23.75 mg, 190.0 mg, 90.0 mg, 47.5 mg, 37.5 mg, 75.0 mg

Oral, Tablet, , Tablet - Oral, Tablet, film coated, Tablet, film coated - Oral, Intravenous, Injection, solution, Injection, solution - Intravenous, Tablet, film coated, extended release, Tablet, film coated, extended release - Oral, Tablet, extended release, Tablet, extended release - Oral, Injection, Injection - Intravenous, Kit, Solution - Intravenous, Solution, Capsule, extended release, Capsule, extended release - Oral, Tablet, coated - Oral, Tablet, coated

Heart Attack

, 50.0 mg, 100.0 mg, 5.0 mg/mL, 25.0 mg, 200.0 mg, 0.5 mg, 0.25 mg, 1.0 mg/mL, 23.75 mg, 190.0 mg, 90.0 mg, 47.5 mg, 37.5 mg, 75.0 mg

Oral, Tablet, , Tablet - Oral, Tablet, film coated, Tablet, film coated - Oral, Intravenous, Injection, solution, Injection, solution - Intravenous, Tablet, film coated, extended release, Tablet, film coated, extended release - Oral, Tablet, extended release, Tablet, extended release - Oral, Injection, Injection - Intravenous, Kit, Solution - Intravenous, Solution, Capsule, extended release, Capsule, extended release - Oral, Tablet, coated - Oral, Tablet, coated

Hypertensive disease

, 50.0 mg, 100.0 mg, 5.0 mg/mL, 25.0 mg, 200.0 mg, 0.5 mg, 0.25 mg, 1.0 mg/mL, 23.75 mg, 190.0 mg, 90.0 mg, 47.5 mg, 37.5 mg, 75.0 mg

Oral, Tablet, , Tablet - Oral, Tablet, film coated, Tablet, film coated - Oral, Intravenous, Injection, solution, Injection, solution - Intravenous, Tablet, film coated, extended release, Tablet, film coated, extended release - Oral, Tablet, extended release, Tablet, extended release - Oral, Injection, Injection - Intravenous, Kit, Solution - Intravenous, Solution, Capsule, extended release, Capsule, extended release - Oral, Tablet, coated - Oral, Tablet, coated

Hypertension

, 50.0 mg, 100.0 mg, 5.0 mg/mL, 25.0 mg, 200.0 mg, 0.5 mg, 0.25 mg, 1.0 mg/mL, 23.75 mg, 190.0 mg, 90.0 mg, 47.5 mg, 37.5 mg, 75.0 mg

Oral, Tablet, , Tablet - Oral, Tablet, film coated, Tablet, film coated - Oral, Intravenous, Injection, solution, Injection, solution - Intravenous, Tablet, film coated, extended release, Tablet, film coated, extended release - Oral, Tablet, extended release, Tablet, extended release - Oral, Injection, Injection - Intravenous, Kit, Solution - Intravenous, Solution, Capsule, extended release, Capsule, extended release - Oral, Tablet, coated - Oral, Tablet, coated

Migraine Disorders

, 50.0 mg, 100.0 mg, 5.0 mg/mL, 25.0 mg, 200.0 mg, 0.5 mg, 0.25 mg, 1.0 mg/mL, 23.75 mg, 190.0 mg, 90.0 mg, 47.5 mg, 37.5 mg, 75.0 mg

Oral, Tablet, , Tablet - Oral, Tablet, film coated, Tablet, film coated - Oral, Intravenous, Injection, solution, Injection, solution - Intravenous, Tablet, film coated, extended release, Tablet, film coated, extended release - Oral, Tablet, extended release, Tablet, extended release - Oral, Injection, Injection - Intravenous, Kit, Solution - Intravenous, Solution, Capsule, extended release, Capsule, extended release - Oral, Tablet, coated - Oral, Tablet, coated

Atrial Fibrillation

, 50.0 mg, 100.0 mg, 5.0 mg/mL, 25.0 mg, 200.0 mg, 0.5 mg, 0.25 mg, 1.0 mg/mL, 23.75 mg, 190.0 mg, 90.0 mg, 47.5 mg, 37.5 mg, 75.0 mg

Oral, Tablet, , Tablet - Oral, Tablet, film coated, Tablet, film coated - Oral, Intravenous, Injection, solution, Injection, solution - Intravenous, Tablet, film coated, extended release, Tablet, film coated, extended release - Oral, Tablet, extended release, Tablet, extended release - Oral, Injection, Injection - Intravenous, Kit, Solution - Intravenous, Solution, Capsule, extended release, Capsule, extended release - Oral, Tablet, coated - Oral, Tablet, coated

Thyroid Crisis

, 50.0 mg, 100.0 mg, 5.0 mg/mL, 25.0 mg, 200.0 mg, 0.5 mg, 0.25 mg, 1.0 mg/mL, 23.75 mg, 190.0 mg, 90.0 mg, 47.5 mg, 37.5 mg, 75.0 mg

Oral, Tablet, , Tablet - Oral, Tablet, film coated, Tablet, film coated - Oral, Intravenous, Injection, solution, Injection, solution - Intravenous, Tablet, film coated, extended release, Tablet, film coated, extended release - Oral, Tablet, extended release, Tablet, extended release - Oral, Injection, Injection - Intravenous, Kit, Solution - Intravenous, Solution, Capsule, extended release, Capsule, extended release - Oral, Tablet, coated - Oral, Tablet, coated

Migraine

, 50.0 mg, 100.0 mg, 5.0 mg/mL, 25.0 mg, 200.0 mg, 0.5 mg, 0.25 mg, 1.0 mg/mL, 23.75 mg, 190.0 mg, 90.0 mg, 47.5 mg, 37.5 mg, 75.0 mg

Oral, Tablet, , Tablet - Oral, Tablet, film coated, Tablet, film coated - Oral, Intravenous, Injection, solution, Injection, solution - Intravenous, Tablet, film coated, extended release, Tablet, film coated, extended release - Oral, Tablet, extended release, Tablet, extended release - Oral, Injection, Injection - Intravenous, Kit, Solution - Intravenous, Solution, Capsule, extended release, Capsule, extended release - Oral, Tablet, coated - Oral, Tablet, coated

Hypesthesia

, 50.0 mg, 100.0 mg, 5.0 mg/mL, 25.0 mg, 200.0 mg, 0.5 mg, 0.25 mg, 1.0 mg/mL, 23.75 mg, 190.0 mg, 90.0 mg, 47.5 mg, 37.5 mg, 75.0 mg

Oral, Tablet, , Tablet - Oral, Tablet, film coated, Tablet, film coated - Oral, Intravenous, Injection, solution, Injection, solution - Intravenous, Tablet, film coated, extended release, Tablet, film coated, extended release - Oral, Tablet, extended release, Tablet, extended release - Oral, Injection, Injection - Intravenous, Kit, Solution - Intravenous, Solution, Capsule, extended release, Capsule, extended release - Oral, Tablet, coated - Oral, Tablet, coated

Hypesthesia

, 50.0 mg, 100.0 mg, 5.0 mg/mL, 25.0 mg, 200.0 mg, 0.5 mg, 0.25 mg, 1.0 mg/mL, 23.75 mg, 190.0 mg, 90.0 mg, 47.5 mg, 37.5 mg, 75.0 mg

Oral, Tablet, , Tablet - Oral, Tablet, film coated, Tablet, film coated - Oral, Intravenous, Injection, solution, Injection, solution - Intravenous, Tablet, film coated, extended release, Tablet, film coated, extended release - Oral, Tablet, extended release, Tablet, extended release - Oral, Injection, Injection - Intravenous, Kit, Solution - Intravenous, Solution, Capsule, extended release, Capsule, extended release - Oral, Tablet, coated - Oral, Tablet, coated

Hemodynamically Stable

, 50.0 mg, 100.0 mg, 5.0 mg/mL, 25.0 mg, 200.0 mg, 0.5 mg, 0.25 mg, 1.0 mg/mL, 23.75 mg, 190.0 mg, 90.0 mg, 47.5 mg, 37.5 mg, 75.0 mg

Oral, Tablet, , Tablet - Oral, Tablet, film coated, Tablet, film coated - Oral, Intravenous, Injection, solution, Injection, solution - Intravenous, Tablet, film coated, extended release, Tablet, film coated, extended release - Oral, Tablet, extended release, Tablet, extended release - Oral, Injection, Injection - Intravenous, Kit, Solution - Intravenous, Solution, Capsule, extended release, Capsule, extended release - Oral, Tablet, coated - Oral, Tablet, coated

Tachycardia, Supraventricular

, 50.0 mg, 100.0 mg, 5.0 mg/mL, 25.0 mg, 200.0 mg, 0.5 mg, 0.25 mg, 1.0 mg/mL, 23.75 mg, 190.0 mg, 90.0 mg, 47.5 mg, 37.5 mg, 75.0 mg

Oral, Tablet, , Tablet - Oral, Tablet, film coated, Tablet, film coated - Oral, Intravenous, Injection, solution, Injection, solution - Intravenous, Tablet, film coated, extended release, Tablet, film coated, extended release - Oral, Tablet, extended release, Tablet, extended release - Oral, Injection, Injection - Intravenous, Kit, Solution - Intravenous, Solution, Capsule, extended release, Capsule, extended release - Oral, Tablet, coated - Oral, Tablet, coated

Warnings

Metoprolol Tartrate has seven restrictions. If you suffer from any of the circumstances listed in the table below, Metoprolol Tartrate should not be administered.

Metoprolol Tartrate Contraindications

Condition

Risk Level

Notes

Severe Hypersensitivity Reactions

Do Not Combine

Metoprolol may interact with Pulse Frequency

Heart Block

Do Not Combine

Shock, Cardiogenic

Do Not Combine

Heart Decompensation

Do Not Combine

Pulse Frequency

Do Not Combine

severe bradycardia

Do Not Combine

Sick Sinus Syndrome

Do Not Combine

There are 20 known major drug interactions with Metoprolol Tartrate.

Common Metoprolol Tartrate Drug Interactions

Drug Name

Risk Level

Description

4-Bromo-2,5-dimethoxyphenethylamine

Major

The therapeutic efficacy of 4-Bromo-2,5-dimethoxyphenethylamine can be decreased when used in combination with Metoprolol.

Abediterol

Major

The therapeutic efficacy of Abediterol can be decreased when used in combination with Metoprolol.

Adrafinil

Major

The therapeutic efficacy of Adrafinil can be decreased when used in combination with Metoprolol.

Agrostis gigantea pollen

Major

The risk of a hypersensitivity reaction to Agrostis gigantea pollen is increased when it is combined with Metoprolol.

Agrostis stolonifera pollen

Major

The risk of a hypersensitivity reaction to Agrostis stolonifera pollen is increased when it is combined with Metoprolol.

Metoprolol Tartrate Toxicity & Overdose Risk

The toxic dose of metoprolol in rats is 3090-4670mg/kg. Signs of an overdose on this drug include slow heart rate, low blood pressure, difficulty breathing, and heart failure. If someone takes too much metoprolol, it is recommended to induce vomiting followed by treatment for the symptoms. Metoprolol is not known to cause cancer, mutations, or fertility problems. Long-term use at high doses may result in small benign lung tumors.

image of a doctor in a lab doing drug, clinical research

Metoprolol Tartrate Novel Uses: Which Conditions Have a Clinical Trial Featuring Metoprolol Tartrate?

At present, there are 319 ongoing investigations assessing the possible benefits of Metoprolol Tartrate for Hypesthesia, Thyroid Crisis and Hypertensive Disease.

Condition

Clinical Trials

Trial Phases

Atrial Fibrillation

94 Actively Recruiting

Not Applicable, Phase 2, Phase 4, Phase 1, Phase 3, Early Phase 1

Chest Pain

2 Actively Recruiting

Not Applicable, Phase 2, Phase 3

Heart Attack

23 Actively Recruiting

Not Applicable, Phase 1, Phase 4, Phase 2, Early Phase 1, Phase 3

Thyroid Crisis

0 Actively Recruiting

Hypesthesia

8 Actively Recruiting

Not Applicable, Phase 1

Hemodynamically Stable

0 Actively Recruiting

Tachycardia, Supraventricular

0 Actively Recruiting

Migraine

51 Actively Recruiting

Phase 4, Not Applicable, Phase 1, Phase 3, Phase 2, Early Phase 1

Hypesthesia

2 Actively Recruiting

Not Applicable

Hypertension

0 Actively Recruiting

Hypertensive disease

27 Actively Recruiting

Not Applicable, Phase 1, Phase 2, Phase 3

Migraine Disorders

1 Actively Recruiting

Phase 3

Metoprolol Tartrate Reviews: What are patients saying about Metoprolol Tartrate?

5

Patient Review

1/31/2022

Metoprolol Tartrate for Abnormal Heart Rhythm

This medication has been a literal lifesaver. For years it's kept my heart rhythm in check and prevented me from going into A-Fib.

5

Patient Review

12/9/2021

Metoprolol Tartrate for High Blood Pressure

I've been taking this medication for seven years now to help with an irregular heartbeat. When I first started the medication, I experienced some side effects like a fast heartbeat, chest pain, dizziness, drowsiness, and weird dreams. However, overall this medication has helped me a lot by lowering my heart rate and reducing chest pains.

4.7

Patient Review

2/12/2020

Metoprolol Tartrate for High Blood Pressure

This medication has been great for managing my blood pressure. I'm really pleased with the results.

3.7

Patient Review

6/6/2020

Metoprolol Tartrate for Heart Rate Between 100 and 130 Beats Per Minute

I bruise and sometimes even bleed when I lightly bump my arms; it's really quite a problem.

3

Patient Review

1/17/2022

Metoprolol Tartrate for High Blood Pressure

I gained 75 pounds while taking this medication and also experienced bad allergic reactions, whelping, swelling, itching, hair loss, and diarrhea. I can't breathe well because of the weight gain, so I'll be asking my doctor to take me off the medication this week.

2.7

Patient Review

7/25/2022

Metoprolol Tartrate for High Blood Pressure

I decided to stop taking this medication after seeing how many other people had similar issues. I was constantly exhausted but couldn't sleep, and started having horrible nightmares and flu-like symptoms.

2.3

Patient Review

8/28/2022

Metoprolol Tartrate for High Blood Pressure

This treatment lowered my blood pressure in conjunction with the triamterene/htcz, however it also dropped my heart rate too low. I experienced fatigue, lightheadedness, and chest pains as a result.

2.3

Patient Review

6/30/2022

Metoprolol Tartrate for Ventricular Rate Control in Atrial Fibrillation

I take a reduced dose of 25mg, and I'm feeling anxious because my heart rate has decreased.

2

Patient Review

4/3/2022

Metoprolol Tartrate for High Blood Pressure

I've gained 30lbs in the last three months, mostly around my waist. My tinnitus has gotten worse, I have no energy, and I'm feeling depressed. My blood pressure is still high (160/95), and I just generally don't feel good since December. Even my teeth hurt! The doctor says everything is okay, but I don't think they're listening to me at all. I want to get off this medication; at 72, I think I know my body better than anyone else does.

2

Patient Review

6/21/2022

Metoprolol Tartrate for Ventricular Rate Control in Atrial Fibrillation

My healthy and active father was prescribed this medication and has since then been experiencing negative side effects like passing out, sleeping excessively, and loss of balance. I believe that this drug is dangerous and should be taken off the market.

2

Patient Review

7/12/2022

Metoprolol Tartrate for High Blood Pressure

I would not recommend this pill to anyone. It is awful and the side effects linger. It messed up my digestive tract and I am hoping after a few months of not taking it things will get better. I have never felt so horrible in all my life.

2

Patient Review

5/12/2021

Metoprolol Tartrate for Abnormal Heart Rhythm

Almost immediately after starting this medication, I began to experience problems with my vision.

1.7

Patient Review

5/2/2022

Metoprolol Tartrate for High Blood Pressure

I have had terrible side effects from this medication. I can barely walk and am constantly dizzy. My feet are swollen and the pain is unbearable. The doctor says I'm fine, but this is the only thing that has changed in my routine.

1.7

Patient Review

5/3/2022

Metoprolol Tartrate for High Blood Pressure

I have been feeling very dizzy and nauseous since I started taking this medication. My feet are still swollen. I got a blood test and the results were abnormal. This is the only medication I am taking.

1

Patient Review

11/11/2021

Metoprolol Tartrate for High Blood Pressure

Overall, I didn't have a good experience with this medication. I felt ill the entire time I was on it, and it made me extremely exhausted to the point where I could barely walk.
image of drug pills surrounding a glass of water symbolizing drug consumption

Patient Q&A Section about metoprolol tartrate

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

What are side effects of metoprolol tartrate?

"Side effects may include: feeling dizzy or tired; depression; confusion; memory problems; nightmares; difficulty sleeping; diarrhea; or a mild itch or rash."

Answered by AI

What is the difference between metoprolol and metoprolol tartrate?

"The main difference between metoprolol tartrate and metoprolol succinate is that metoprolol tartrate is only available as an immediate-release tablet which means it must be taken several times per day, whereas metoprolol succinate is an extended-release tablet that can be taken once a day."

Answered by AI

What is metoprolol tartrate given for?

"Metoprolol is used in combination with other medications to treat high blood pressure, which can prevent strokes, heart attacks, and kidney problems. This medication is also effective in treating chest pain and improving survival rates after a heart attack."

Answered by AI

What is the best time of day to take metoprolol tartrate?

"This medication should be taken with a meal or just after a meal. The medicine should be taken at the same time each day. The capsule should be swallowed whole and not crushed, chewed, broken, or opened. A Toprol XL tablet can be divided in half if your doctor has told you to do so."

Answered by AI

Clinical Trials for Metoprolol Tartrate

Image of Miles Square Health Center Chicago in Chicago, United States.

Food is Medicine for High Blood Pressure and Obesity

Any Age
All Sexes
Chicago, IL

The goal of this clinical trial is to treat both hypertension and obesity in adults using a food is medicine framework. Participants will be randomized 1:1 to FIM+DASH or usual-care control. The 24-week trial includes a 12-week FIM+DASH intervention followed by a 12-week maintenance period and leverages existing partnerships with community-based organizations for home food delivery and culinary skill-skill building. The main questions it aims to answer are: (1) What is the effect of FIM+DASH vs. usual care control on blood pressure? (2) What is the effect of FIM+DASH vs. usual care control on DASH diet adherence (diet quality), body weight, and waist circumference? (3) How to identify factors associated with the sustainability and scalability of FIM+DASH in real-world settings?

Phase 2
Waitlist Available

Miles Square Health Center Chicago (+3 Sites)

Image of Northwestern University in Chicago, United States.

Exercise Program for Atrial Fibrillation and Heart Failure

60 - 99
All Sexes
Chicago, IL

Atrial fibrillation (AF) and heart failure with preserved ejection fraction (HFpEF) are very common conditions that often occur together and result in worsening symptoms and reduced quality of life (QoL). Limitations being able to participate in activities of daily living is a primary complaint for AF-HFpEF patients, yet effective strategies to address this issue remain limited. While exercise interventions targeting aerobic training (AT) are recommended for patients with AF and HFpEF, unique challenges exist in this patient population who tend to be older. Specifically, many older patients with AF and HFpEF have muscle weakness, sarcopenia and frailty, that can make aerobic-focused exercise difficult and less tolerable. This study proposes that starting with progressive resistance training (PRT) before aerobic exercise may overcome these issues by improving muscle strength, making AT more manageable, and leading to better health outcomes. The goal of this study is to assess whether a sequential exercise program, named 'PREACTIVE' improves how people feel, decrease the amount of symptoms, and their ability to participate in exercise and activities. This study will specifically test a sequenced exercise approach of resistance training followed by aerobic exercise to improve symptoms, and quality of life in AF-HFpEF.

Waitlist Available
Has No Placebo

Northwestern University

Deepika Laddu, PhD

Image of Arizona State University in Phoenix, United States.

App-based Breathing Program for Migraine

18+
All Sexes
Phoenix, AZ

Migraine is one of the most common neurological disorders, characterized by recurrent headaches, sensitivity to light and movement, nausea, and autonomic dysregulation. Although mind-body interventions like biofeedback have shown their efficacy, they remain underutilized due to barriers such as transportation, time constraints, lack of awareness, stigma, and cost. A targeted approach to enhancing HRV is HRV biofeedback (HRVB), a technique using visual or auditory feedback to help people regulate HRV through slow-paced breathing and positive emotional regulation to promote ANS balance and emotional resilience. Investigators will conduct a remotely delivered pilot RCT of an 8-week, 10 min/day, novel app-based HRVB intervention compared to a sham control intervention (matching intervention time and attention with no biofeedback component) in adult with chronic migraine. Investigators hypothesize data collected from the study will: a) support the feasibility and acceptability of the remotely delivered app-based HRVB intervention among adults with chronic migraine, and b) provide insights into refining the intervention by examining patterns of change in migraine and psychological outcomes from pre- to post-intervention.

Waitlist Available
Online Trial

Arizona State University

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Heparin Dosing for Blood Clots and Heart Conditions

18+
All Sexes
Alexandria, VA

The goal of this clinical trial study is to test whether a mathematical calculation, using the patient's gender, weight and kidney function, can better predict a patient's heparin goal dose than a flat number of units per patient weight can. Participants will have the first dose of heparin infusion calculated, after which if adjustments are needed, the Hospital's prebuilt table for results driven dosing for this purpose is used. The researchers will compare the time it takes for the participants to get to the desired goal using the patient's information for calculation versus patients in the past who received the medication using the flat rate. The hypothesis is that the patients with enhanced personal data, gender, weight and kidney function, included for the initial dose, will get to their goal lab value sooner and with less chance of delay or overshooting the goal. A quicker time to goal lab value is beneficial to patients in many ways, including earlier treatment of the clot or coronary issue that the patient is experiencing.

Phase 4
Waitlist Available

Inova Alexandria Hospital

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Embolization for Migraine

18 - 80
All Sexes
Baltimore, MD

This study is to test the safety and feasibility of a procedure called embolization of the middle meningeal arteries (MMA), using a product called Onyx. Embolization creates a plug in the arteries. MMA embolization with Onyx is not approved for use in patients with migraines, but is currently used in patients with subdural hematomas. The FDA is allowing the use of Onyx in this study. It is thought that by using Onyx to block the middle meningeal arteries, the amount of migraine-causing substances which are released into the brain's bloodstream will be reduced. The company that manufactures Onyx, Medtronic, is providing the supplies for this study. Participants will be in the study for about 8 months after enrolling, including 6 months of follow up after the procedure. The participants will be asked to complete a daily headache diary and continue the participant's regular migraine medications. Participants will also have several clinic visits and be asked to provide blood samples for research.

Waitlist Available
Has No Placebo

Johns Hopkins Medicine

Risheng Xu, MD, PhD

Medtronic

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