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Behavioral Intervention
Exercise for Alcohol Use Disorder (Alc-Excr Trial)
N/A
Recruiting
Led By Jesus Chavarria, Ph.D.
Research Sponsored by Western University, Canada
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial Must have
Inclusion Criteria: Heavy social alcohol drinkers (i.e., alcohol drinkers who consume 10-40 standard alcohol beverages per week and participate in 1-5 binge drinking episodes [consume 4+/5+ drinks in a sitting for women/men, respectively]) per week.
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Timeline
Screening 3 weeks
Treatment Varies
Follow Up mid-intervention (32 minutes after prime dose consumption) & post-intervention (44 minutes after prime dose consumption)
Awards & highlights
No Placebo-Only Group
Summary
This trial will study if exercise can reduce alcohol cravings in heavy drinkers & how it affects drink consumption.
Who is the study for?
This trial is for heavy social drinkers who have between 10-40 standard drinks weekly and engage in binge drinking. Participants should be those who typically consume four or more (women) or five or more (men) drinks in one sitting.
What is being tested?
The study is testing if walking on a treadmill, which is mild-to-moderate exercise, can help reduce the craving for alcohol and decrease the consumption of an alcohol-like placebo compared to doing a distracting activity like coloring.
What are the potential side effects?
Since this trial involves exercise and coloring as interventions, there are minimal expected side effects. Exercise may cause physical fatigue or muscle soreness, while coloring is not associated with any known side effects.
Eligibility Criteria
Inclusion Criteria
You may be eligible if you check “Yes” for the criteria belowSelect...
I drink 10-40 alcoholic drinks weekly and have 1-5 binge drinking sessions.
Select...
N/A
Timeline
Screening ~ 3 weeks3 visits
Treatment ~ Varies
Follow Up ~ mid-intervention (32 minutes after prime dose consumption) & post-intervention (44 minutes after prime dose consumption)
Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~mid-intervention (32 minutes after prime dose consumption) & post-intervention (44 minutes after prime dose consumption)
Treatment Details
Study Objectives
Study objectives can provide a clearer picture of what you can expect from a treatment.Primary study objectives
Changes in alcohol craving after alcohol prime dose
Post-intervention alcohol beverage consumption
Secondary study objectives
Changes in alcohol wanting after alcohol prime dose
Awards & Highlights
No Placebo-Only Group
All patients enrolled in this study will receive some form of active treatment.
Trial Design
2Treatment groups
Experimental Treatment
Group I: ExerciseExperimental Treatment1 Intervention
Moderate intensity treadmill walking (40%-59% of heartrate reserve).
Group II: ColoringExperimental Treatment1 Intervention
Coloring in an adult coloring book as a distraction activity
Treatment
First Studied
Drug Approval Stage
How many patients have taken this drug
Coloring
2018
N/A
~120
Exercise
2016
Completed Phase 1
~820
Find a Location
Who is running the clinical trial?
Western University, CanadaLead Sponsor
253 Previous Clinical Trials
58,502 Total Patients Enrolled
Jesus Chavarria, Ph.D.Principal InvestigatorWestern University
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