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Behavioural Intervention

Alcohol for Cognitive Effects (REACT Trial)

N/A
Recruiting
Research Sponsored by University of Washington
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Aged 21-25
Be between 18 and 65 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up baseline and after alcohol consumption in the laboratory (an average of approximately 1 hour after baseline)
Awards & highlights

Summary

This trial aims to study how alcohol impacts the attention of young adults in both controlled lab settings and real-life situations using phone-based tasks. The main questions the trial seeks to answer are how well these tasks

Who is the study for?
This trial is for young adults interested in understanding how alcohol affects their attention. Participants will complete tasks before and after drinking a set amount of alcohol in a lab, and then on their phones over eight weekends.
What is being tested?
The study tests the impact of alcohol on attention by having participants do cognitive tasks in the lab and through an app. It aims to see if these effects influence risk-taking behavior.
What are the potential side effects?
Since the intervention involves consuming alcohol, potential side effects include typical reactions to intoxication such as impaired coordination, slowed reflexes, altered judgment, mood changes, and hangover symptoms.

Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below
Select...
I am between 21 and 25 years old.

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~baseline and after alcohol consumption in the laboratory (an average of approximately 1 hour after baseline)
This trial's timeline: 3 weeks for screening, Varies for treatment, and baseline and after alcohol consumption in the laboratory (an average of approximately 1 hour after baseline) for reporting.

Treatment Details

Study Objectives

Study objectives can provide a clearer picture of what you can expect from a treatment.
Primary study objectives
Central Counting Task (phone)
Peripheral Probe Identification Task (phone)
Visual Categorization Task (phone)
Secondary study objectives
Auditory Categorization Task (desktop)
Central Counting Task (desktop)
Peripheral Probe Identification Task (desktop)

Side effects data

From 2017 Phase 2 trial • 17 Patients • NCT01779024
59%
Increased Appetite
41%
Somnolence
35%
Euphoric mood
29%
Fatigue
12%
Memory impairment
12%
Hyperhidrosis
12%
Dizziness
12%
Nausea
6%
Feeling hot
6%
Headache
6%
Flushing
6%
Decreased appetite
100%
80%
60%
40%
20%
0%
Study treatment Arm
Ghrelin
Placebo

Trial Design

1Treatment groups
Experimental Treatment
Group I: AlcoholExperimental Treatment1 Intervention

Find a Location

Who is running the clinical trial?

National Institute on Alcohol Abuse and Alcoholism (NIAAA)NIH
823 Previous Clinical Trials
1,161,206 Total Patients Enrolled
University of WashingtonLead Sponsor
1,791 Previous Clinical Trials
1,905,406 Total Patients Enrolled
~67 spots leftby Aug 2025
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