Perioperative Pain Management for Shoulder Arthritis

N/A

Waitlist Available

Research Sponsored by Lawson Health Research Institute

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

Be older than 18 years old

Timeline

Screening 3 weeks

Treatment Varies

Follow Up 12 months

Awards & highlights

No Placebo-Only Group

Summary

This trial looks at improving the effectiveness and efficiency of shoulder replacement surgery. It looks at the use of perioperative pain management strategies and careful patient selection to reduce length of stay and improve effectiveness.

Who is the study for?

This trial is for individuals undergoing total shoulder arthroplasty, who have conditions like osteoarthritis, rheumatoid arthritis, rotator cuff issues or fractures. It's not specified who can't join the trial.

What is being tested?

The study tests a pain management cocktail during shoulder replacement surgery. This mix includes saline solution, ropivacaine (a numbing drug), morphine (painkiller), epinephrine (to reduce bleeding) and ketorolac (for inflammation).

What are the potential side effects?

Possible side effects may include nausea from morphine; numbness or weakness due to ropivacaine; increased heart rate from epinephrine; stomach issues or kidney problems from ketorolac.

Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ 12 months

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~12 months

This trial's timeline: 3 weeks for screening, Varies for treatment, and 12 months for reporting.

Treatment Details

Study Objectives

Study objectives can provide a clearer picture of what you can expect from a treatment.

Primary study objectives

Pain VAS

Secondary study objectives

ASES Shoulder Score

Analgesia Diary

Constant Score

+5 more

Awards & Highlights

No Placebo-Only Group

All patients enrolled in this study will receive some form of active treatment.

Trial Design

2Treatment groups

Experimental Treatment

Active Control

Group I: Local Infiltration AnesthesiaExperimental Treatment1 Intervention

High volume local infiltration anesthesia with 100 mL of 0.9% normal saline (57ml), 0.5% ropivacaine (40 ml), 10 mg morphine (10 mg/ml), 0.1 mg of epinephrine (0.1 mg/ml), and 30 mg of ketorolac (30 mg/ml) divided equally into a 20 ml five-zone field infiltration into the suprascapular notch/posterior capsule (suprascapular and axillary nerves), coracobrachialis muscle, anterior deltoid muscle, superior pectoralis major muscle, and skin incision at the conclusion of the procedure by the treating surgeon.

Group II: Regional Brachial Plexus BlockadeActive Control1 Intervention

Ultrasound guided brachial plexus blocade with 10 ml of 0.5% ropivacaine using a high frequency linear array transducer.

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