← Back to Search

The CoAGulation Biomarkers and Atrial Fibrillation (COAG-AF) Pilot Study

New Orleans, LA
N/A
Recruiting
Led By Nassir Marrouche, MD
Research Sponsored by Tulane University
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up 1 year
Awards & highlights
No Placebo-Only Group

Summary

The aim of the Correlation Of CoAGulation-Atrial Fibrillation (COAG-AF) study is to prove that an increase in pro-thrombotic biomarkers in AF is associated with an increase in AF burden. Secondary objectives of the study are the following: * To investigate the impact of catheter ablation on serum pro-thrombotic biomarkers in patients with AF. * To correlate coagulation biomarkers with imaging features such as, the degree of fibrosis found on Late Gadolinium Enhancement Magnetic Resonance Imaging (LGE-MRI) scans, which is a part of standard of care. * To determine baseline values of coagulation and pro-thrombotic biomarkers in the AF population and compare those baseline values with the general population values. * To compare central and peripheral thrombotic biomarkers in patients with atrial fibrillation.

See full description
Eligible Conditions
  • Atrial Fibrillation

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~1 year
This trial's timeline: 3 weeks for screening, Varies for treatment, and 1 year for reporting.

Treatment Details

Study Objectives

Study objectives can provide a clearer picture of what you can expect from a treatment.
Primary study objectives
Measure the change in Asymmetric dimethyl arginine (ADMA) in relation to atrial fibrillation burden
Measure the change in B-thromboglobulin in relation to atrial fibrillation burden
Measure the change in D-dimers in relation to atrial fibrillation burden
+7 more
Secondary study objectives
Determine the association between Asymmetric dimethyl arginine (ADMA) and degree of fibrosis in MRI findings
Determine the association between B-thromboglobulin and degree of fibrosis in MRI findings
Determine the association between D-dimers and degree of fibrosis in MRI findings
+7 more

Awards & Highlights

No Placebo-Only Group
All patients enrolled in this study will receive some form of active treatment.

Find a Location

Closest Location:Tulane University Medical Center· New Orleans, LA

Who is running the clinical trial?

Tulane UniversityLead Sponsor
127 Previous Clinical Trials
258,962 Total Patients Enrolled
5 Trials studying Atrial Fibrillation
1,102 Patients Enrolled for Atrial Fibrillation
Nassir Marrouche, MDPrincipal InvestigatorTulane University
7 Previous Clinical Trials
11,388 Total Patients Enrolled
4 Trials studying Atrial Fibrillation
688 Patients Enrolled for Atrial Fibrillation
~6 spots leftby Dec 2026
Unbiased ResultsWe believe in providing patients with all the options.
Your Data Stays Your DataWe only share your information with the clinical trials you're trying to access.
Verified Trials OnlyAll of our trials are run by licensed doctors, researchers, and healthcare companies.
Back to top