Understanding Episodic Memory in Epilepsy

Recruiting in Palo Alto (17 mi)

Overseen ByUeli Rutishauser, PhD

Age: Any Age

Sex: Any

Travel: May be covered

Time Reimbursement: Varies

Trial Phase: Academic

Waitlist Available

Sponsor: Cedars-Sinai Medical Center

No Placebo Group

Trial Summary

What is the purpose of this trial?This trial involves monitoring brain cell activity and using small electrical pulses to understand how memories are formed and used. It targets patients with drug-resistant epilepsy because their treatment allows direct study of brain activity. By observing and stimulating brain cells, researchers aim to learn more about memory and decision-making.

Eligibility Criteria

This trial is for individuals aged 13 or older with intractable epilepsy who are already undergoing invasive monitoring. Participants should have an IQ over 70 and be able to understand and perform tasks on a computer by pressing buttons. Those unable to complete the tasks due to cognitive, psychological limits, or pain cannot join.

Inclusion Criteria

I am 13 years old or older.

I have severe epilepsy and am undergoing special monitoring.

Participant Groups

The study aims to understand how humans learn, recall information, and make decisions using various devices: Cedrus response pad for inputs; Adtech micro-electrodes, Neurolynx system for brain activity recording; Blackrock stimulator possibly for stimulating specific brain areas during tests.

1Treatment groups

Experimental Treatment

Group I: Behavioral TestingExperimental Treatment1 Intervention

Behavioral and Neuronal Recordings