TNF Inhibitor
Stopping TNF Inhibitors for Rheumatoid Arthritis
Recruiting3 awardsPhase 4
Washington, District of Columbia
This trial is testing whether people in remission from RA can stay in remission after discontinuing use of a TNF inhibitor drug, and whether clinical, imaging and immunological measurements can help predict which patients will flare after discontinuing the drug.
Janus Kinase (JAK) Inhibitor
Baricitinib for Rheumatoid Arthritis
Recruiting3 awardsPhase 4
Flagstaff, Arizona
This trial compares the safety of two treatments for rheumatoid arthritis, focusing on the risk of blood clots. One treatment is baricitinib, an oral medication used for moderate to severe cases.
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Trials for RA Patients
Behavioural Intervention
Family Physician Consultations for Rheumatoid Arthritis
Recruiting1 award1 criteria
Waterloo, Ontario
This trial aims to see if adding a family doctor to a team of rheumatologists can help improve the overall health of people with rheumatoid arthritis. The family doctor will focus on vaccinations, heart
Probiotic
Probiotic R-2487 for Rheumatoid Arthritis
Recruiting1 awardPhase 1
Lebanon, New Hampshire
This trial is testing a probiotic supplement taken by mouth to see if it is safe and well-tolerated in people with Rheumatoid Arthritis. The goal is to find out if improving gut health can help reduce inflammation and manage symptoms of the disease. Probiotics, including various Lactobacillus species, have been studied for their potential to alleviate symptoms of rheumatoid arthritis by normalizing gut microbiota and reducing inflammation.
Shared Decision Making Intervention for Rheumatoid Arthritis
Recruiting1 award
San Francisco, California
This trial will test whether a shared decision making intervention can help reduce disease activity, improve medication adherence, and increase patient knowledge about RA in Veterans Affairs (VA) patients with RA.
Behavioral Intervention
Multidisciplinary Care for Rheumatoid Arthritis
Recruiting1 award
Torrance, California
This trial will test a new intervention for socioeconomically disadvantaged Hispanic adults with rheumatoid arthritis to see if it improves remission rates. The intervention is based on a partnership between the patient and the extended healthcare team, and includes things like self-management education and technology-based at-home monitoring of symptoms.
Trials for Osteoarthritis Patients
Joint Replacement
Nexel Total Elbow Replacement for Elbow Osteoarthritis
Recruiting1 award
Golden, Colorado
This trial aims to confirm the safety and effectiveness of the Zimmer Nexel Total Elbow in patients needing their first or a revised elbow replacement. The device replaces damaged parts of the elbow to help reduce pain and improve function. The Zimmer Nexel Total Elbow is used to replace damaged parts of the elbow, primarily in patients with severe elbow pain and joint destruction.
Orthopedic Implant
Ankle Implant for Arthritis
Recruiting1 award
Sacramento, California
This trial studies a special ankle implant for patients needing ankle surgery. It aims to see how well the implant works in reducing pain and improving function. The implants have been developed to improve stability and longevity, with advancements in design and materials.
Phase 3 Trials
Device
Vagus Nerve Stimulation for Rheumatoid Arthritis
Recruiting1 awardPhase 3
Covina, California
This trial will assess the safety and efficacy of a new device designed to treat rheumatoid arthritis by stimulating the vagus nerve. The study will enroll 250 subjects at 40 sites, who will either receive active or non-active stimulation. There will be a one-way crossover of control subjects to active stimulation after 12 weeks, and all subjects will receive active stimulation for the next 180 weeks to evaluate long-term safety.
Biological Response Modifier
DMARDs for Rheumatoid Arthritis
Recruiting2 awardsPhase 3
Omaha, Nebraska
This trial is testing whether a certain type of arthritis medication can help predict clinical responses to other types of arthritis medication. All patients will receive a starting dose of the medication being tested, which may be adjusted by the investigator as needed. If a subject becomes intolerant to the medication being tested, the subject will be withdrawn from the study. Data from the study will be collected at the end of the trial.
Janus Kinase (JAK) Inhibitor
Long-Term Safety of Filgotinib for Rheumatoid Arthritis
Recruiting2 awardsPhase 3
Huntsville, Alabama
This trial aims to check the ongoing safety and tolerability of filgotinib, a medication that helps reduce inflammation and pain. The study focuses on people with rheumatoid arthritis who have already used filgotinib in a previous study. Filgotinib works by blocking enzymes that cause inflammation, helping to reduce swelling and pain. Filgotinib has been approved for the treatment of rheumatoid arthritis in adults who respond inadequately to other treatments in Europe and Japan.
Trials With No Placebo
Behavioural Intervention
Family Physician Consultations for Rheumatoid Arthritis
Recruiting1 award1 criteria
Waterloo, Ontario
This trial aims to see if adding a family doctor to a team of rheumatologists can help improve the overall health of people with rheumatoid arthritis. The family doctor will focus on vaccinations, heart
Probiotic
Probiotic R-2487 for Rheumatoid Arthritis
Recruiting1 awardPhase 1
Lebanon, New Hampshire
This trial is testing a probiotic supplement taken by mouth to see if it is safe and well-tolerated in people with Rheumatoid Arthritis. The goal is to find out if improving gut health can help reduce inflammation and manage symptoms of the disease. Probiotics, including various Lactobacillus species, have been studied for their potential to alleviate symptoms of rheumatoid arthritis by normalizing gut microbiota and reducing inflammation.
Shared Decision Making Intervention for Rheumatoid Arthritis
Recruiting1 award
San Francisco, California
This trial will test whether a shared decision making intervention can help reduce disease activity, improve medication adherence, and increase patient knowledge about RA in Veterans Affairs (VA) patients with RA.
Procedure
Ulcer Healing Analysis for Inflammatory Bowel Disease
Recruiting1 award7 criteria
Lexington, Kentucky
This trial involves taking small pieces of tissue from the colon to study how ulcers heal. It includes patients with inflammatory bowel disease, arthritis, and healthy individuals to compare healing processes. Researchers will examine how genes work and how cells produce energy to understand healing.
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Frequently Asked Questions
Do I need insurance to participate in a trial?
Almost all clinical trials will cover the cost of the 'trial drug' — so no insurance is required for this. For trials where this trial drug is given alongside an already-approved medication, there may be a cost (which your insurance would normally cover).
Is there any support for travel costs?
Many of the teams running clinical trials will cover the cost of transportation to-and-from their care center.
Will I know what medication I am taking?
This depends on the specific study. If you're worried about receiving a placebo, you can actively filter out these trials using our search.
How long do clinical trials last?
Some trials will only require a single visit, while others will continue until your disease returns. It's fairly common for a trial to last somewhere between 1 and 6 months.
Do you verify all the trials on your website?
All of the trials listed on Power have been formally registered with the US Food and Drug Administration. Beyond this, some trials on Power have been formally 'verified' if the team behind the trial has completed an additional level of verification with our team.
How quickly will I hear back from a clinical trial?
Sadly, this response time can take anywhere from 6 hours to 2 weeks. We're working hard to speed up how quickly you hear back — in general, verified trials respond to patients within a few days.