Chlorhexidine gluconate bathing for Surgical Site Infection

N/A

Waitlist Available

Led By Joshua T Swan, Pharm.D.

Research Sponsored by Joshua Swan

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

Be older than 18 years old

Timeline

Screening 3 weeks

Treatment Varies

Follow Up up to 28 days

Awards & highlights

Approved for 5 Other Conditions

All Individual Drugs Already Approved

Summary

This prospective, randomized, controlled trial will compare the incidence of nosocomial infections (composite of primary bloodstream infections, catheter-associated urinary tract infections, ventilator-associated pneumonia, and surgical site infections) that occur in intensive care unit (ICU) patients bathed with 2% chlorhexidine solution versus patients who receive standard bathing (soap and water or non-medicated cloths).

Eligible Conditions

Ventilator-associated pneumonia
Surgical Site Infection
Catheter-associated urinary tract infection
Community-Acquired Infections
Cross Contamination

Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ up to 28 days

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~up to 28 days

This trial's timeline: 3 weeks for screening, Varies for treatment, and up to 28 days for reporting.

Treatment Details

Study Objectives

Study objectives can provide a clearer picture of what you can expect from a treatment.

Primary study objectives

Incidence of Nosocomial Infection

Secondary study objectives

ICU Length of Stay in Days

Incidence of Skin Irritation

Awards & Highlights

Approved for 5 Other Conditions

This treatment demonstrated efficacy for 5 other conditions.

All Individual Drugs Already Approved

Therapies where all constituent drugs have already been approved are likely to have better-understood side effect profiles.

Trial Design

2Treatment groups

Active Control

Placebo Group

Group I: Chlorhexidine gluconate bathingActive Control1 Intervention

Upon study enrollment, patients will be bathed with a 2% chlorhexidine gluconate solution on study day 1 and every 48 hours until study completion. The patient will be bathed using standard bathing (non-medicated cloths or soap and water) on study day 2 and every 48 hours after that.

Group II: Standard bathingPlacebo Group1 Intervention

Upon study enrollment, patients will be bathed using standard bathing (non-medicated cloths or soap and water) daily.

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