Your session is about to expire
← Back to Search
Antiseptic
Trial of 2% Chlorhexidine Bathing on Nosocomial Infections in the Surgical Intensive Care Unit
N/A
Waitlist Available
Led By Joshua T Swan, Pharm.D.
Research Sponsored by Joshua Swan
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial Must have
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up up to 28 days
Awards & highlights
Approved for 5 Other Conditions
All Individual Drugs Already Approved
Summary
This prospective, randomized, controlled trial will compare the incidence of nosocomial infections (composite of primary bloodstream infections, catheter-associated urinary tract infections, ventilator-associated pneumonia, and surgical site infections) that occur in intensive care unit (ICU) patients bathed with 2% chlorhexidine solution versus patients who receive standard bathing (soap and water or non-medicated cloths).
Eligible Conditions
- Ventilator-associated pneumonia
- Surgical Site Infection
- Catheter-associated urinary tract infection
- Community-Acquired Infections
- Cross Contamination
Timeline
Screening ~ 3 weeks3 visits
Treatment ~ Varies
Follow Up ~ up to 28 days
Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~up to 28 days
Treatment Details
Study Objectives
Study objectives can provide a clearer picture of what you can expect from a treatment.Primary study objectives
Incidence of Nosocomial Infection
Secondary study objectives
ICU Length of Stay in Days
Incidence of Skin Irritation
Awards & Highlights
Approved for 5 Other Conditions
This treatment demonstrated efficacy for 5 other conditions.
All Individual Drugs Already Approved
Therapies where all constituent drugs have already been approved are likely to have better-understood side effect profiles.
Trial Design
2Treatment groups
Active Control
Placebo Group
Group I: Chlorhexidine gluconate bathingActive Control1 Intervention
Upon study enrollment, patients will be bathed with a 2% chlorhexidine gluconate solution on study day 1 and every 48 hours until study completion. The patient will be bathed using standard bathing (non-medicated cloths or soap and water) on study day 2 and every 48 hours after that.
Group II: Standard bathingPlacebo Group1 Intervention
Upon study enrollment, patients will be bathed using standard bathing (non-medicated cloths or soap and water) daily.
Find a Location
Who is running the clinical trial?
Texas Southern UniversityOTHER
Joshua SwanLead Sponsor
The Methodist Hospital Research InstituteOTHER
287 Previous Clinical Trials
81,430 Total Patients Enrolled
Joshua T Swan, Pharm.D.Principal InvestigatorThe Methodist Hospital, Texas Southern University