SickKids for Intestinal Failure-associated Liver Disease

Children with intestinal failure (IF) depend on parenteral nutrition (PN). This is associated with frequent and various complications such as metabolic bone disease, micronutrient deficiencies and abnormal body composition. Due to advancements in care, many patients with IF are able to wean off PN; they are so called PN graduates. It is currently not well known how often complications do occur after weaning off PN, and which patients are at highest risk of developing these complications. We therefore propose a multicenter prospective study on pediatric patients with IF who weaned off PN.