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N/A

Cardiometabolic Benefits of Potatoes Mediated Along the Gut-Vessel Axis in Adults With Metabolic Syndrome

N/A
Waitlist Available
Led By Richard Bruno, PhD, RD
Research Sponsored by Ohio State University
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be between 18 and 65 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up day 14 postprandial (0, 30, 60, 90, 120 minutes)

Summary

This study is focused on assessing potential health benefits of daily consumption of potatoes, specifically its resistant starch content (i.e. nondigestible carbohydrate), on blood vessel and gut health function in adults with metabolic syndrome. It is expected that the daily consumption of potatoes for two weeks, within a diet that follows the Dietary Guidelines for Americans, will improve blood vessel function in association with decreasing gut permeability ("leaky gut") that results in the absorption of bacterial toxins that reside in the intestine. Outcomes will therefore support dietary recommendations for potatoes to support vascular and gastrointestinal health.

Eligible Conditions
  • Endotoxemia
  • Cardiovascular Disease
  • Endothelial Dysfunction
  • Postprandial Hyperglycemia
  • Gut Health

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~day 14 postprandial (0, 30, 60, 90, 120 minutes)
This trial's timeline: 3 weeks for screening, Varies for treatment, and day 14 postprandial (0, 30, 60, 90, 120 minutes) for reporting.

Treatment Details

Study Objectives

Study objectives can provide a clearer picture of what you can expect from a treatment.
Primary study objectives
Endotoxin
Vascular endothelial function
Secondary study objectives
Day 0 diastolic blood pressure
Day 0 height
Day 0 systolic blood pressure
+38 more

Trial Design

2Treatment groups
Experimental Treatment
Placebo Group
Group I: Potato dietExperimental Treatment1 Intervention
Potato consumed daily for 2 weeks
Group II: Bagel dietPlacebo Group1 Intervention
Bagel consumed daily for 2 weeks

Find a Location

Who is running the clinical trial?

Ohio State UniversityLead Sponsor
871 Previous Clinical Trials
655,433 Total Patients Enrolled
4 Trials studying Endotoxemia
144 Patients Enrolled for Endotoxemia
Alliance for Potato Research and EducationOTHER
14 Previous Clinical Trials
615 Total Patients Enrolled
Richard Bruno, PhD, RDPrincipal Investigator - Ohio State University
Ohio State University
5 Previous Clinical Trials
136 Total Patients Enrolled
2 Trials studying Endotoxemia
80 Patients Enrolled for Endotoxemia
~4 spots leftby Dec 2025