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Comparison of the Alpha-2 Agonists for Prevention of Intraocular Pressure Elevation After Selective Laser Trabeculoplasty

N/A
Waitlist Available
Led By Vladimir S Yakopson, MD
Research Sponsored by Walter Reed Army Medical Center
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up up to 5 years
Awards & highlights
Approved for 5 Other Conditions
All Individual Drugs Already Approved
No Placebo-Only Group

Summary

The purpose of the study is to compare the safety and efficacy of two drops used to lower eye pressure when given prior to a glaucoma laser procedure.

Eligible Conditions
  • Glaucoma
  • Ocular Hypertension

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~up to 5 years
This trial's timeline: 3 weeks for screening, Varies for treatment, and up to 5 years for reporting.

Treatment Details

Awards & Highlights

Approved for 5 Other Conditions
This treatment demonstrated efficacy for 5 other conditions.
All Individual Drugs Already Approved
Therapies where all constituent drugs have already been approved are likely to have better-understood side effect profiles.
No Placebo-Only Group
All patients enrolled in this study will receive some form of active treatment.

Trial Design

2Treatment groups
Active Control
Group I: AActive Control1 Intervention
Eyes receiving Brimonidine 0.1% (Alphagan) prior to SLT
Group II: IActive Control1 Intervention
Eyes receiving Apraclonidine 0.5% (Iopidine) prior to SLT

Find a Location

Who is running the clinical trial?

Walter Reed Army Medical CenterLead Sponsor
69 Previous Clinical Trials
20,896 Total Patients Enrolled
Vladimir S Yakopson, MDPrincipal InvestigatorWalter Reed AMC
~2 spots leftby Jan 2026