← Back to Search

Injectable Medication Platforms for Medical Treatments

N/A

Recruiting

Led By Gaurav Gupta, MD

Research Sponsored by Canadian Forces Health Services Centre Ottawa

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

Be older than 18 years old

Timeline

Screening 3 weeks

Treatment Varies

Follow Up immediately after intervention

Awards & highlights

No Placebo-Only Group

Summary

This trial is testing different types of autoinjectors to see which is the most efficient at delivering medication.

Who is the study for?

This trial is for adults over 18 who can consent and have not used medication injections in the past year. It's not for healthcare workers with recent injection experience or those with conditions affecting thinking or hand coordination, as well as anyone with recent substance use.

What is being tested?

The study compares different methods of injecting emergency medications: autoinjectors, standard injectors, and prefilled syringes. The goal is to find out which method delivers medicine most efficiently during emergencies like severe allergies or overdoses.

What are the potential side effects?

While the trial focuses on delivery methods rather than medications themselves, potential side effects may include pain at the injection site, bruising, allergic reactions to components of the injector device, or complications from incorrect usage.

Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ immediately after intervention

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~immediately after intervention

This trial's timeline: 3 weeks for screening, Varies for treatment, and immediately after intervention for reporting.

Treatment Details

Study Objectives

Study objectives can provide a clearer picture of what you can expect from a treatment.

Primary study objectives

Change in medication Injection/delivery time for each trial

Secondary study objectives

Number of injection failures and/or injuries associated with each trial

Perceived difficulty of injection based on type of system

Awards & Highlights

No Placebo-Only Group

All patients enrolled in this study will receive some form of active treatment.

Trial Design

1Treatment groups

Experimental Treatment

Group I: Injection ScenarioExperimental Treatment3 Interventions

For each scenario participants will be asked to administer/inject the "medication" (likely saline or air) using various methods: 1) standard protocol , 2) Autoinjector 3) Pre-filled syringes. For each scenario the appropriate medication administration type will have to be selected amongst groups of options: 1) autoinjectors equivalents (ie medication, needle and syringe attached) 2) prefilled syringes where a needle is attached prior to administration; and 3) standard protocol (i.e. drawing medication from the vial and injecting via syringe/22 gauge needle). Medications options will include 1) Naloxone (opioid overdose) 2) Epinephrine (anaphylaxis) 3) Tranexamic acid (bleeding).

Treatment

First Studied

Drug Approval Stage

How many patients have taken this drug

Autoinjector

2016

Completed Phase 3

~440

Do I qualify?Apply below to find out