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Animal-Based Protein

Plant-Based vs Beef Protein for Obesity

N/A

Recruiting

Led By Bryant Keirns

Research Sponsored by Ball State University

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

Not been diagnosed with a cardiometabolic conditions (e.g., type 2 diabetes)

Does not regularly take anti-inflammatory drugs (more than 2x week)

Must not have

Been diagnosed with a chronic inflammatory condition (e.g., rheumatoid arthritis, inflammatory bowel disease)

Postmenopausal status (females only)

Timeline

Screening 3 weeks

Treatment Varies

Follow Up through study completion, up to 1 year.

Awards & highlights

Summary

"This trial aims to compare the effects of a plant-based meat alternative (like Beyond Meat) with beef on factors like metabolism, digestion, and inflammation. The study will look at how these effects differ between

Who is the study for?

This trial is for individuals who are either of normal weight or have overweight/obesity. It aims to understand how a high-fat meal with plant-based protein (Beyond Meat) compares to one with animal protein (beef).

What is being tested?

The study tests the immediate effects on metabolism, digestion, and inflammation when participants consume a Western-style high-fat meal that includes either Beyond Meat or beef.

What are the potential side effects?

While not explicitly stated, potential side effects may include digestive discomfort or changes in metabolic markers due to the high-fat content of the meals being tested.

Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below

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I do not have type 2 diabetes or similar heart-related conditions.

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I do not regularly take anti-inflammatory drugs more than twice a week.

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I do not take medication to lower my cholesterol.

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I have not been diagnosed with any heart diseases.

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I am a woman and have not gone through menopause.

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I am between 18 and 50 years old.

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I do not take medication to lower my blood sugar.

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I do not have a chronic inflammatory condition like rheumatoid arthritis or IBD.

Exclusion Criteria

You may be eligible for the trial if you check “No” for criteria below:

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I have a chronic inflammatory condition like rheumatoid arthritis.

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I am a woman and have gone through menopause.

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I have been diagnosed with a heart condition.

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I regularly take anti-inflammatory drugs more than twice a week.

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I am taking medication to lower my cholesterol.

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I have been diagnosed with a condition like type 2 diabetes.

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I take medication to lower my blood sugar.

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I am younger than 18 or older than 50.

Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ through study completion, up to 1 year.

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~through study completion, up to 1 year.

This trial's timeline: 3 weeks for screening, Varies for treatment, and through study completion, up to 1 year. for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.

Primary outcome measures

Serum interleukin (IL)-6

Serum lipopolysaccharide

Serum lipopolysaccharide binding protein (LBP)

+2 more

Secondary outcome measures

Glucose

HDL-C

Triglycerides

Other outcome measures

Body composition

Systolic and diastolic pressure

Trial Design

2Treatment groups

Experimental Treatment

Active Control

Group I: Meal Consumption with Beyond MeatExperimental Treatment1 Intervention

During the Beyond Meat arm, participants will consume a high-fat meal containing Beyond Meat (rather than beef). Meals will be otherwise identical.

Group II: Meal Consumption with BeefActive Control1 Intervention

During the Beef arm, participants will consume a high-fat meal containing beef (rather than Beyond Meat). Meals will be otherwise identical.

0 / 16Eligibility criteria met

Find a Location

Who is running the clinical trial?

Ball State UniversityLead Sponsor

8 Previous Clinical Trials

612 Total Patients Enrolled

Bryant KeirnsPrincipal InvestigatorBall State University

1 Previous Clinical Trials

10 Total Patients Enrolled

~16 spots leftby Sep 2025

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