~7 spots leftby Mar 2026

Exercise for Sarcopenia

Recruiting in Palo Alto (17 mi)
+1 other location
Age: 65+
Sex: Any
Travel: May be covered
Time Reimbursement: Varies
Trial Phase: Academic
Waitlist Available
Sponsor: Baltimore VA Medical Center
No Placebo Group

Trial Summary

What is the purpose of this trial?This trial aims to see if starting with aerobic exercise before strength training can help older adults with muscle loss due to aging. The idea is that better blood flow from aerobic exercise will make muscles respond better to strength training. Participants will start with either aerobic exercise or strength training, and their muscle size, strength, and function will be measured.

Eligibility Criteria

This trial is for older adults with a body mass index between 18-32.5 who have moderate sarcopenia, which means they've lost muscle mass as they've aged. They must be non-smokers and not currently exercise regularly. People with diabetes, cancer, lung or kidney diseases, or physical impairments that prevent exercising cannot participate.

Exclusion Criteria

I cannot exercise due to a physical impairment.
I have been diagnosed with diabetes, cancer, lung, or kidney disease.

Participant Groups

The study is testing if doing aerobic exercises can increase the number of small blood vessels in muscles and improve the benefits of strength training in older adults with sarcopenia to help them regain muscle mass and function.
2Treatment groups
Experimental Treatment
Active Control
Group I: Aerobic exercise training followed by resistance trainingExperimental Treatment2 Interventions
Participants in this arm will undergo 3 months of aerobic exercise training, followed by 3 months of strength training
Group II: Resistance training followed by aerobic exercise trainingActive Control2 Interventions
Participants in this arm will undergo 3 months of strength training, followed by 3 months of aerobic exercise training

Find A Clinic Near You

Research locations nearbySelect from list below to view details:
University of Maryland, Baltimore & Baltimore VA Medical CenterBaltimore, MD
University of MarylandCollege Park, MD
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Who is running the clinical trial?

Baltimore VA Medical CenterLead Sponsor
University of Maryland, BaltimoreCollaborator

References