Exercise for Sarcopenia

Recruiting in Palo Alto (17 mi)

+1 other location

Age: 65+

Sex: Any

Travel: May be covered

Time Reimbursement: Varies

Trial Phase: Academic

Waitlist Available

Sponsor: Baltimore VA Medical Center

No Placebo Group

Trial Summary

What is the purpose of this trial?This trial aims to see if starting with aerobic exercise before strength training can help older adults with muscle loss due to aging. The idea is that better blood flow from aerobic exercise will make muscles respond better to strength training. Participants will start with either aerobic exercise or strength training, and their muscle size, strength, and function will be measured.

Eligibility Criteria

This trial is for older adults with a body mass index between 18-32.5 who have moderate sarcopenia, which means they've lost muscle mass as they've aged. They must be non-smokers and not currently exercise regularly. People with diabetes, cancer, lung or kidney diseases, or physical impairments that prevent exercising cannot participate.

Exclusion Criteria

I cannot exercise due to a physical impairment.

I have been diagnosed with diabetes, cancer, lung, or kidney disease.

Participant Groups

The study is testing if doing aerobic exercises can increase the number of small blood vessels in muscles and improve the benefits of strength training in older adults with sarcopenia to help them regain muscle mass and function.

2Treatment groups

Experimental Treatment

Active Control

Group I: Aerobic exercise training followed by resistance trainingExperimental Treatment2 Interventions

Participants in this arm will undergo 3 months of aerobic exercise training, followed by 3 months of strength training

Group II: Resistance training followed by aerobic exercise trainingActive Control2 Interventions

Participants in this arm will undergo 3 months of strength training, followed by 3 months of aerobic exercise training