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Resistance Exercise for Type 1 Diabetes

N/A

Recruiting

Research Sponsored by University of Alberta

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

Female with type 1 diabetes diagnosed for at least 1 year

At least 12 months since last menstrual period

Must not have

Individuals who are treated with medications (other than insulin) that affect glucose metabolism (e.g. atypical antipsychotics, corticosteroids)

A history of cardiovascular disease

Timeline

Screening 3 weeks

Treatment Varies

Follow Up from 0 minutes to 45 minutes, and from 45 minutes to 105 minutes

Awards & highlights

No Placebo-Only Group

Summary

This trial will help researchers understand how different types of exercise affect blood sugar levels in post-menopausal women with type 1 diabetes, in order to design better exercise programs for this population.

Who is the study for?

This trial is for post-menopausal women with Type 1 Diabetes living near Edmonton, Alberta. They should have been diagnosed at least a year ago and not had a menstrual period in the last 12 months. Participants must be able to do resistance exercise but can't join if they have high blood pressure, cardiovascular disease history, are on certain medications, or have conditions affecting exercise ability.

What is being tested?

The study tests how different resistance exercises affect blood sugar levels in participants. One group will do low resistance but high repetition weight lifting (3 sets of 15-20 reps), while another does moderate resistance and repetitions (3 sets of 8-10 reps). The goal is to see which method impacts blood glucose during and after exercise.

What are the potential side effects?

Potential side effects may include an increased risk of hypoglycemia (low blood sugar) during or after exercising. This could lead to symptoms like shakiness, sweating, confusion, heart palpitations or even fainting.

Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below

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I am a woman diagnosed with type 1 diabetes for over a year.

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It has been over a year since my last menstrual period.

Exclusion Criteria

You may be eligible for the trial if you check “No” for criteria below:

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I am taking medication that affects my blood sugar levels, excluding insulin.

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I have a history of heart disease.

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I have changed my insulin management in the last two months.

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I often have sudden low blood sugar levels.

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I have injuries that prevent me from doing strength training exercises.

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I have severe nerve pain or numbness in my hands or feet.

Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ 0 to 6 hours post exercise, overnight post exercise (midnight to 6 am) and 24 hours post exercise

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~0 to 6 hours post exercise, overnight post exercise (midnight to 6 am) and 24 hours post exercise

This trial's timeline: 3 weeks for screening, Varies for treatment, and 0 to 6 hours post exercise, overnight post exercise (midnight to 6 am) and 24 hours post exercise for reporting.

Treatment Details

Study Objectives

Study objectives can provide a clearer picture of what you can expect from a treatment.

Primary study objectives

Blood glucose

Secondary study objectives

Mean continuous glucose monitoring (CGM) glucose

carbohydrate supplementation

coefficient of variation (CV)

+6 more

Awards & Highlights

No Placebo-Only Group

All patients enrolled in this study will receive some form of active treatment.

Trial Design

1Treatment groups

Experimental Treatment

Group I: All participantsExperimental Treatment2 Interventions

All participants will be in a single arm that undergoes two separate interventions. These interventions will include a high repetition, low resistance protocol, and a moderate repetition, moderate intensity protocol.

0 / 8Eligibility criteria met