Popular Trials
Device
Optilume™ BPH Catheter System for Enlarged Prostate
This trial is testing a special catheter designed to treat men with an enlarged prostate. The device helps to open up the urinary passage, making it easier to urinate. The goal is to see if this treatment is safe and effective for these patients.
Expander System
XFLO Expander System for Enlarged Prostate
This trial is testing a new device called the Mercury Expander system, which aims to help men who have trouble urinating because of an enlarged prostate. The device works by opening up the blocked area in the urinary tract, making it easier for urine to pass through. The Mercury Expander System is a novel implantable device designed to treat lower urinary tract symptoms due to benign prostatic hyperplasia.
Prostate Implant
Urocross Expander System for Enlarged Prostate
This trial is testing a new device called the Urocross Expander System/Retrieval Sheath. It is designed to help men with an enlarged prostate (BPH) who have trouble urinating. The device works by widening the urinary passage to make it easier to urinate.
Urethral Expander System
ProVee Urethral Expander System for Benign Prostatic Hyperplasia
This trial is testing a new device called the ProVee Urethral Expander System. It aims to help men who have trouble urinating because of an enlarged prostate. The device works by widening the urethra, making it easier for urine to pass through.
Popular Filters
Trials for Enlarged Prostate Patients
Laser Therapy
Thulium Fiber vs MOSES Holmium Laser for Enlarged Prostate
This trial compares two laser treatments for men with an enlarged prostate. These treatments aim to remove excess prostate tissue with less bleeding and faster recovery than traditional methods. One treatment uses a Thulium laser, while the other uses a Holmium laser.
Procedure
Traditional vs Top-Down HoLEP for Enlarged Prostate
This trial will compare the two most common types of surgery for treating an enlarged prostate. HoLEP is a newer, less invasive type of surgery that has a shorter hospital stay, but a longer learning curve for surgeons. The "Top-Down" HoLEP technique is a novel technique which offers potential benefits to the Traditional HoLEP procedure, including decreased complexity, a reduced learning curve.
Device
Zenflow Spring System for Enlarged Prostate
This trial aims to test the safety and effectiveness of the Zenflow Spring System, a device designed to help men with an enlarged prostate urinate more easily. The spring is placed in the urinary tract to keep it open, reducing symptoms with minimal side effects. The target group is men who suffer from urinary problems due to an enlarged prostate.
Trials for Lower Urinary Tract Symptoms Patients
Procedure
Traditional vs Top-Down HoLEP for Enlarged Prostate
This trial will compare the two most common types of surgery for treating an enlarged prostate. HoLEP is a newer, less invasive type of surgery that has a shorter hospital stay, but a longer learning curve for surgeons. The "Top-Down" HoLEP technique is a novel technique which offers potential benefits to the Traditional HoLEP procedure, including decreased complexity, a reduced learning curve.
Procedure
Aquablation Therapy for Enlarged Prostate
This trial will assess the use of the Aquablation therapy, a robotic system that combines cystoscopic visualization, ultrasound imaging and advanced planning software to treat LUTS due to BPH and compare the percentage of patients discharged the same day of surgery.
Procedure
Moses 2.0 Laser Treatment for Enlarged Prostate
This trial aims to see if using Moses 2.0 during prostate laser treatment can make the procedure more effective and safer by reducing tissue damage, improving visibility, and reducing bleeding. This trial tests
Behavioral Intervention
Exercise for Enlarged Prostate
This trial is studying the effects of a 12-week exercise program on older men with urinary problems caused by an enlarged prostate. The men will be randomly assigned to either the exercise program or a health education
Behavioral Intervention
Pelvic Floor Physical Therapy for Stress Urinary Incontinence
This trial is being conducted to see if starting pelvic floor physical therapy before prostate surgery can help manage or prevent urinary incontinence (leaking) after the surgery. Pelvic floor physical therapy involves exercises
Trials With No Placebo
Laser Therapy
Thulium Fiber vs MOSES Holmium Laser for Enlarged Prostate
This trial compares two laser treatments for men with an enlarged prostate. These treatments aim to remove excess prostate tissue with less bleeding and faster recovery than traditional methods. One treatment uses a Thulium laser, while the other uses a Holmium laser.
Procedure
Traditional vs Top-Down HoLEP for Enlarged Prostate
This trial will compare the two most common types of surgery for treating an enlarged prostate. HoLEP is a newer, less invasive type of surgery that has a shorter hospital stay, but a longer learning curve for surgeons. The "Top-Down" HoLEP technique is a novel technique which offers potential benefits to the Traditional HoLEP procedure, including decreased complexity, a reduced learning curve.
Frequently Asked Questions
Introduction to benign prostatic hyperplasia
What are the top hospitals conducting benign prostatic hyperplasia research?
When it comes to cutting-edge clinical trials addressing benign prostatic hyperplasia (BPH), hospitals across the United States are making notable contributions. In Cleveland, Ohio, University Hospitals Cleveland Medical Center takes the lead with one active BPH trial and an equally impressive history of conducting a single trial for this condition thus far. This medical center has demonstrated its commitment to advancing research in BPH since recording its first trial in 2023. Similarly, UH Brainard Medical Bldg in Lyndhurst and UH Regional Hospitals - Richmond Campus in Richmond Heights have also embarked on their own respective active BPH trials and hold a record of one completed trial each—both initiated in 2023.
Moving northward to Thunder Bay Regional Health Sciences Centre situated in Thunder Bay, Canada, we find another medical facility dedicated to exploring solutions for individuals affected by BPH. With one ongoing clinical trial focused on this condition and having commenced their inaugural investigation back in 2022, this center is actively contributing to expanding our understanding of potential treatments for the condition.
Finally, located southwards all away down into Hialeah is Urology Specialist Group where they too are pioneering similar efforts towards finding resolutions tending only one current clinical experiment alongside having successfully conducted singular such investigations since way back as 2020.
These hospitals represent beacons of hope for those suffering from BPH while exemplifying dedication towards advancements within urological health care. Although there may appear few active trials presently underway across these institutions collectively, it's essential to acknowledge that every initiative contributes substantially toward enhanced patient outcomes and better quality of life moving forward
Which are the best cities for benign prostatic hyperplasia clinical trials?
For benign prostatic hyperplasia clinical trials, several cities have emerged as leaders in research and development. Thunder Bay, Ontario takes the lead with 2 active trials investigating treatments such as Thulium Fibre Laser and Top-Down HoLEP. Following closely behind is Cleveland, Ohio, along with its neighboring cities Lyndhurst and Richmond Heights, each hosting 1 active trial focused on Intravesical Botox injection among other interventions. Additionally, Hialeah, Florida joins the ranks with 1 ongoing trial exploring SoracteLite(TM) TPLA for BPH. These cities offer individuals affected by benign prostatic hyperplasia opportunities to participate in cutting-edge clinical trials that strive for improved treatment options and better quality of life.
Which are the top treatments for benign prostatic hyperplasia being explored in clinical trials?
Clinical trials exploring potential treatments for benign prostatic hyperplasia (BPH) have brought several promising options to the forefront. Prostate Artery Embolization, a procedure designed to shrink the prostate gland by blocking its blood supply, is currently being tested in two active trials and has been involved in five all-time BPH trials since its introduction in 2014. Intravesical Botox injection, a minimally invasive treatment that involves injecting botulinum toxin directly into the bladder wall, shows promise with one active trial and one all-time trial dedicated to BPH research since its first listing in 2023. Thulium Fibre Laser therapy and SoracteLite(TM) TPLA are also undergoing investigation through clinical trials for their efficacy against BPH, each with one active trial and one all-time study focused on this condition. As these studies progress, they provide hope for improved management of benign prostatic hyperplasia.
What are the most recent clinical trials for benign prostatic hyperplasia?
Recent clinical trials offer promising advancements in the treatment of benign prostatic hyperplasia (BPH). A Phase 4 trial explores a new treatment group specifically tailored for BPH, potentially providing improved outcomes for patients. Additionally, SoracteLite(TM) TPLA is being investigated in a Phase 1 study as a potential therapeutic option for BPH. These innovative trials aim to address the challenges associated with this condition and enhance patient care.
What benign prostatic hyperplasia clinical trials were recently completed?
Recently completed clinical trials for benign prostatic hyperplasia have provided valuable insights into potential treatment options. In September 2019, Urovant Sciences GmbH successfully concluded a trial investigating the efficacy of Vibegron in addressing this condition. Similarly, another trial sponsored by Urovant Sciences GmbH reached completion in March 2019 and also focused on evaluating the effects of Vibegron. These important studies shed light on the ongoing efforts to find innovative therapeutic approaches for individuals with benign prostatic hyperplasia.