Fluphenazine Hydrochloride

Chorea, Depression, Sedation + 4 more
Treatment
1 FDA approval
20 Active Studies for Fluphenazine Hydrochloride

What is Fluphenazine Hydrochloride

FluphenazineThe Generic name of this drug
Treatment SummaryTrifluoperazine is a medication used to treat mental disorders such as psychosis. It works in a similar way to chlorpromazine and is used to reduce symptoms like hallucinations, delusions, and agitation.
Fluphenazine Hydrochlorideis the brand name
image of different drug pills on a surface
Fluphenazine Hydrochloride Overview & Background
Brand Name
Generic Name
First FDA Approval
How many FDA approvals?
Fluphenazine Hydrochloride
Fluphenazine
1987
181

Approved as Treatment by the FDA

Fluphenazine, also known as Fluphenazine Hydrochloride, is approved by the FDA for 1 uses including Schizophrenia .
Schizophrenia
Helps manage Psychosis

Effectiveness

How Fluphenazine Hydrochloride Affects PatientsFluphenazine is a medication used to treat schizophrenia and other psychosis-related disorders. It is not known to be effective for managing the behavior of people with mental disabilities.
How Fluphenazine Hydrochloride works in the bodyFluphenazine works by blocking certain receptors in the brain related to dopamine. This affects processes like body temperature, wakefulness, and vomiting. It also reduces the release of hormones from the hypothalamus and pituitary gland.

When to interrupt dosage

The measure of Fluphenazine Hydrochloride is contingent upon the diagnosed complaint, including Schizophrenia, Gilles de la Tourette's Syndrome and Sedation therapy. The dosage amount varies, based on the mode of delivery (e.g. Tablet, film coated - Oral or Intramuscular) indicated in the table beneath.
Condition
Dosage
Administration
Sedation therapy
, 5.0 mg/mL, 0.5 mg/mL, 2.5 mg, 5.0 mg, 10.0 mg, 1.0 mg, 25.0 mg/mL, 2.5 mg/mL, 2.0 mg, 125.0 mg/mL, 100.0 mg/mL
, Oral, Solution, concentrate, Solution, concentrate - Oral, Elixir, Elixir - Oral, Tablet, film coated, Tablet, film coated - Oral, Intramuscular; Subcutaneous, Injection, solution, Injection, solution - Intramuscular; Subcutaneous, Tablet, Tablet - Oral, Intramuscular, Injection, solution - Intramuscular, Liquid, Liquid - Intramuscular; Subcutaneous, Liquid - Intramuscular, Solution, Solution - Intramuscular; Subcutaneous, Injection, Injection - Intramuscular; Subcutaneous
Schizophrenia
, 5.0 mg/mL, 0.5 mg/mL, 2.5 mg, 5.0 mg, 10.0 mg, 1.0 mg, 25.0 mg/mL, 2.5 mg/mL, 2.0 mg, 125.0 mg/mL, 100.0 mg/mL
, Oral, Solution, concentrate, Solution, concentrate - Oral, Elixir, Elixir - Oral, Tablet, film coated, Tablet, film coated - Oral, Intramuscular; Subcutaneous, Injection, solution, Injection, solution - Intramuscular; Subcutaneous, Tablet, Tablet - Oral, Intramuscular, Injection, solution - Intramuscular, Liquid, Liquid - Intramuscular; Subcutaneous, Liquid - Intramuscular, Solution, Solution - Intramuscular; Subcutaneous, Injection, Injection - Intramuscular; Subcutaneous
Depression
, 5.0 mg/mL, 0.5 mg/mL, 2.5 mg, 5.0 mg, 10.0 mg, 1.0 mg, 25.0 mg/mL, 2.5 mg/mL, 2.0 mg, 125.0 mg/mL, 100.0 mg/mL
, Oral, Solution, concentrate, Solution, concentrate - Oral, Elixir, Elixir - Oral, Tablet, film coated, Tablet, film coated - Oral, Intramuscular; Subcutaneous, Injection, solution, Injection, solution - Intramuscular; Subcutaneous, Tablet, Tablet - Oral, Intramuscular, Injection, solution - Intramuscular, Liquid, Liquid - Intramuscular; Subcutaneous, Liquid - Intramuscular, Solution, Solution - Intramuscular; Subcutaneous, Injection, Injection - Intramuscular; Subcutaneous
Tourette Syndrome
, 5.0 mg/mL, 0.5 mg/mL, 2.5 mg, 5.0 mg, 10.0 mg, 1.0 mg, 25.0 mg/mL, 2.5 mg/mL, 2.0 mg, 125.0 mg/mL, 100.0 mg/mL
, Oral, Solution, concentrate, Solution, concentrate - Oral, Elixir, Elixir - Oral, Tablet, film coated, Tablet, film coated - Oral, Intramuscular; Subcutaneous, Injection, solution, Injection, solution - Intramuscular; Subcutaneous, Tablet, Tablet - Oral, Intramuscular, Injection, solution - Intramuscular, Liquid, Liquid - Intramuscular; Subcutaneous, Liquid - Intramuscular, Solution, Solution - Intramuscular; Subcutaneous, Injection, Injection - Intramuscular; Subcutaneous
Chorea
, 5.0 mg/mL, 0.5 mg/mL, 2.5 mg, 5.0 mg, 10.0 mg, 1.0 mg, 25.0 mg/mL, 2.5 mg/mL, 2.0 mg, 125.0 mg/mL, 100.0 mg/mL
, Oral, Solution, concentrate, Solution, concentrate - Oral, Elixir, Elixir - Oral, Tablet, film coated, Tablet, film coated - Oral, Intramuscular; Subcutaneous, Injection, solution, Injection, solution - Intramuscular; Subcutaneous, Tablet, Tablet - Oral, Intramuscular, Injection, solution - Intramuscular, Liquid, Liquid - Intramuscular; Subcutaneous, Liquid - Intramuscular, Solution, Solution - Intramuscular; Subcutaneous, Injection, Injection - Intramuscular; Subcutaneous
Sedation
, 5.0 mg/mL, 0.5 mg/mL, 2.5 mg, 5.0 mg, 10.0 mg, 1.0 mg, 25.0 mg/mL, 2.5 mg/mL, 2.0 mg, 125.0 mg/mL, 100.0 mg/mL
, Oral, Solution, concentrate, Solution, concentrate - Oral, Elixir, Elixir - Oral, Tablet, film coated, Tablet, film coated - Oral, Intramuscular; Subcutaneous, Injection, solution, Injection, solution - Intramuscular; Subcutaneous, Tablet, Tablet - Oral, Intramuscular, Injection, solution - Intramuscular, Liquid, Liquid - Intramuscular; Subcutaneous, Liquid - Intramuscular, Solution, Solution - Intramuscular; Subcutaneous, Injection, Injection - Intramuscular; Subcutaneous
Huntington Disease
, 5.0 mg/mL, 0.5 mg/mL, 2.5 mg, 5.0 mg, 10.0 mg, 1.0 mg, 25.0 mg/mL, 2.5 mg/mL, 2.0 mg, 125.0 mg/mL, 100.0 mg/mL
, Oral, Solution, concentrate, Solution, concentrate - Oral, Elixir, Elixir - Oral, Tablet, film coated, Tablet, film coated - Oral, Intramuscular; Subcutaneous, Injection, solution, Injection, solution - Intramuscular; Subcutaneous, Tablet, Tablet - Oral, Intramuscular, Injection, solution - Intramuscular, Liquid, Liquid - Intramuscular; Subcutaneous, Liquid - Intramuscular, Solution, Solution - Intramuscular; Subcutaneous, Injection, Injection - Intramuscular; Subcutaneous

Warnings

Fluphenazine Hydrochloride Contraindications
Condition
Risk Level
Notes
Brain Injuries
Do Not Combine
Disease
Do Not Combine
Liver Damage
Do Not Combine
Mental Depression
Do Not Combine
Hypnotics
Do Not Combine
Brain Injuries
Do Not Combine
Comatose
Do Not Combine
There are 20 known major drug interactions with Fluphenazine Hydrochloride.
Common Fluphenazine Hydrochloride Drug Interactions
Drug Name
Risk Level
Description
Amisulpride
Major
Fluphenazine may increase the antipsychotic activities of Amisulpride.
Astemizole
Major
The metabolism of Astemizole can be decreased when combined with Fluphenazine.
Azelastine
Major
Fluphenazine may increase the central nervous system depressant (CNS depressant) activities of Azelastine.
Dacomitinib
Major
The metabolism of Dacomitinib can be decreased when combined with Fluphenazine.
Deutetrabenazine
Major
The risk or severity of adverse effects can be increased when Fluphenazine is combined with Deutetrabenazine.
image of a doctor in a lab doing drug, clinical research

Fluphenazine Hydrochloride Novel Uses: Which Conditions Have a Clinical Trial Featuring Fluphenazine Hydrochloride?

640 active studies are currently in progress to assess the potential of Fluphenazine Hydrochloride to provide relief from Huntington Disease, Sedation therapy and Chorea.
Condition
Clinical Trials
Trial Phases
Sedation therapy
0 Actively Recruiting
Sedation
2 Actively Recruiting
Phase 3, Not Applicable
Tourette Syndrome
0 Actively Recruiting
Depression
333 Actively Recruiting
Phase 1, Phase 2, Early Phase 1, Not Applicable, Phase 4, Phase 3
Huntington Disease
10 Actively Recruiting
Phase 1, Phase 2, Phase 3, Not Applicable
Chorea
0 Actively Recruiting
Schizophrenia
37 Actively Recruiting
Early Phase 1, Not Applicable, Phase 4

Fluphenazine Hydrochloride Reviews: What are patients saying about Fluphenazine Hydrochloride?

5Patient Review
5/3/2014
Fluphenazine Hydrochloride for Schizophrenia
I've taken this drug twice now, 25mg each time by I.M., and I haven't had any issues. If anything, it's helped me feel more relaxed.
5Patient Review
8/29/2019
Fluphenazine Hydrochloride for Schizophrenia
Fluphenazine was a great replacement for thiothixene when it was discontinued. I experienced no side effects and found it to be just as effective, if not more so.
5Patient Review
5/22/2008
Fluphenazine Hydrochloride for Schizophrenia
4.7Patient Review
11/20/2013
Fluphenazine Hydrochloride for Mental Disorder with Loss of Normal Personality & Reality
I find that this medication is really effective when used in conjunction with lithium. It helps me sleep at night and keeps my mood stable. I haven't had any side effects during the 2+ years I've been on it, (2mg) but when my dr started reducing my dose I had 24 hrs of muscle spasms in my mouth going through withdrawal.
4.7Patient Review
7/9/2009
Fluphenazine Hydrochloride for Schizophrenia
Another person who reviewed this medication said they experienced muscle stiffness in their mouth, so my doctor recommended Bendryl. If you experience this side effect, talk to your doctor.
3.7Patient Review
3/20/2009
Fluphenazine Hydrochloride for Schizophrenia
I found that this medicine made me talk in my sleep, and I also experienced muscle stiffness in my mouth. It was a scary feeling - I thought I was going to die!
3.7Patient Review
12/16/2009
Fluphenazine Hydrochloride for Mental Disorder with Loss of Normal Personality & Reality
I started taking this medication and the first night I had some really bad nightmares. If anyone else has experienced this, please let me know in the comments below.
3.7Patient Review
10/28/2007
Fluphenazine Hydrochloride for Mental Disorder with Loss of Normal Personality & Reality
2.3Patient Review
6/21/2015
Fluphenazine Hydrochloride for Schizophrenia
Unfortunately, I had to stop taking this medicine because it caused me intense restlessness.
image of drug pills surrounding a glass of water symbolizing drug consumption

Patient Q&A Section about fluphenazine hydrochloride

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

What does fluphenazine do to the brain?

"This medication is used to treat symptoms of schizophrenia. Fluphenazine belongs to a class of medications called phenothiazines. It works by affecting the balance of natural chemicals in the brain."

Answered by AI

Does fluphenazine have side effects?

"The following effects may occur: drowsiness, lethargy, dizziness, lightheadedness, nausea, loss of appetite, sweating, dry mouth, blurred vision, headache, and constipation. If you experience any of these effects, contact your doctor or pharmacist."

Answered by AI

What is fluphenazine hydrochloride used for?

"Fluphenazine is an antipsychotic medication used to treat schizophrenia and psychotic symptoms such as hallucinations, delusions, and hostility. It can also be prescribed for other uses; so if you're curious, ask your doctor or pharmacist for more information."

Answered by AI

Is fluphenazine a sedative?

"Fluphenazine is a potent phenothiazine neuroleptic used to treat schizophrenia in humans. In horses, it is used off-label for its anxiolytic and long-acting sedative effects."

Answered by AI

Clinical Trials for Fluphenazine Hydrochloride

Have you considered Fluphenazine Hydrochloride clinical trials? We made a collection of clinical trials featuring Fluphenazine Hydrochloride, we think they might fit your search criteria.
Have you considered Fluphenazine Hydrochloride clinical trials? We made a collection of clinical trials featuring Fluphenazine Hydrochloride, we think they might fit your search criteria.
Have you considered Fluphenazine Hydrochloride clinical trials? We made a collection of clinical trials featuring Fluphenazine Hydrochloride, we think they might fit your search criteria.
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