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What is Levalbuterol Hydrochloride
LevosalbutamolThe Generic name of this drug
Treatment SummaryLevosalbutamol, also known as levalbuterol, is a medication used to treat asthma and COPD. It is an advanced version of salbutamol that works by stimulating the β2 adrenergic receptors. Levosalbutamol is an enantiomerically pure form of salbutamol, meaning it only contains the active ingredient and no other chemicals, making it more effective and safer than the racemic mixture of salbutamol.
Xopenexis the brand name
Levalbuterol Hydrochloride Overview & Background
Brand Name
Generic Name
First FDA Approval
How many FDA approvals?
Xopenex
Levosalbutamol
1999
79
Approved as Treatment by the FDA
Levosalbutamol, commonly known as Xopenex, is approved by the FDA for 2 uses which include Bronchial Spasm and prophylaxis of Bronchospasm .Bronchial Spasm
prophylaxis of Bronchospasm
Effectiveness
How Levalbuterol Hydrochloride Affects PatientsThis drug works by making the muscles around the airways in the lungs relax, which allows more air to flow and relieves difficulty breathing.
How Levalbuterol Hydrochloride works in the bodyLevosalbutamol works by activating a receptor on the airway smooth muscle. This stimulates a cascade of reactions that ultimately relax the muscles and reduce the release of substances from mast cells. This helps reduce symptoms of asthma attacks.
When to interrupt dosage
The advocated dosage of Levalbuterol Hydrochloride is contingent upon the diagnosed state, including Chronic Obstructive Pulmonary Disease (COPD), Bronchospasm and prophylaxis of Bronchospasm. The dose fluctuates, per the technique of delivery (e.g. Respiratory (inhalation) or Oral) outlined in the following table.Condition
Dosage
Administration
Bronchial Spasm
, 0.045 mg, 12.5 mg/mL, 1.25 mg/mL, 0.63 mg/mL, 0.31 mg/mL
, Oral, Aerosol, metered, Aerosol, metered - Oral, Respiratory (inhalation), Solution, concentrate, Solution, concentrate - Respiratory (inhalation), Solution, Solution - Respiratory (inhalation)
prophylaxis of Bronchospasm
, 0.045 mg, 12.5 mg/mL, 1.25 mg/mL, 0.63 mg/mL, 0.31 mg/mL
, Oral, Aerosol, metered, Aerosol, metered - Oral, Respiratory (inhalation), Solution, concentrate, Solution, concentrate - Respiratory (inhalation), Solution, Solution - Respiratory (inhalation)
Chronic Obstructive Pulmonary Disease
, 0.045 mg, 12.5 mg/mL, 1.25 mg/mL, 0.63 mg/mL, 0.31 mg/mL
, Oral, Aerosol, metered, Aerosol, metered - Oral, Respiratory (inhalation), Solution, concentrate, Solution, concentrate - Respiratory (inhalation), Solution, Solution - Respiratory (inhalation)
Warnings
Levalbuterol Hydrochloride ContraindicationsCondition
Risk Level
Notes
Pulse Frequency
Do Not Combine
Common Levalbuterol Hydrochloride Drug Interactions
Drug Name
Risk Level
Description
2,5-Dimethoxy-4-ethylthioamphetamine
Minor
The risk or severity of hypertension can be increased when Levosalbutamol is combined with 2,5-Dimethoxy-4-ethylthioamphetamine.
5-methoxy-N,N-dimethyltryptamine
Minor
The risk or severity of hypertension can be increased when Levosalbutamol is combined with 5-methoxy-N,N-dimethyltryptamine.
Acemetacin
Minor
The risk or severity of hypertension can be increased when Levosalbutamol is combined with Acemetacin.
Albutrepenonacog alfa
Minor
Levosalbutamol may decrease the excretion rate of Albutrepenonacog alfa which could result in a higher serum level.
Alclofenac
Minor
The risk or severity of hypertension can be increased when Levosalbutamol is combined with Alclofenac.
Levalbuterol Hydrochloride Novel Uses: Which Conditions Have a Clinical Trial Featuring Levalbuterol Hydrochloride?
98 active clinical trials are currently being conducted to evaluate the potential of Levalbuterol Hydrochloride to provide prophylaxis for Bronchospasm, Chronic Obstructive Pulmonary Disease (COPD) and Bronchospasm.Condition
Clinical Trials
Trial Phases
prophylaxis of Bronchospasm
0 Actively Recruiting
Chronic Obstructive Pulmonary Disease
90 Actively Recruiting
Phase 3, Not Applicable, Phase 1, Phase 2, Early Phase 1, Phase 4
Bronchial Spasm
1 Actively Recruiting
Phase 2
Levalbuterol Hydrochloride Reviews: What are patients saying about Levalbuterol Hydrochloride?
4Patient Review
12/28/2012 I took this medication for acute bronchitis and found that it really helped me to breathe. The downside is that I experienced some mild side effects like headaches, tremors, and indigestion issues.
4Patient Review
10/23/2013 This treatment can cause dry mouth and trembling, but it's effective.
Patient Q&A Section about levalbuterol hydrochloride
These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.Is levalbuterol better than albuterol?
"There is no difference in effectiveness or side effects between albuterol and levalbuterol in children with moderate asthma exacerbations."
Answered by AI
What is levalbuterol hcl used for?
"Levalbuterol is used to prevent or treat bronchospasm by relaxing the muscles in the airways. This medicine is also used to treat other lung diseases. Levalbuterol belongs to the family of medicines known as adrenergic bronchodilators."
Answered by AI
Is levalbuterol the same as albuterol?
"Albuterol and levalbuterol are both drugs that are used to treat asthma. They are similar in that they are both bronchodilators. They are not exactly the same, though, as levalbuterol is composed of just R-albuterol, while albuterol is a racemic mixture of both R-albuterol and S-albuterol."
Answered by AI
How quickly does levalbuterol work?
"Steroids are used in asthma to lower inflammation in lungs and Xopenex is used to help you breathe better by opening up your airways. These two types of medications work well together, but they are not the same thing. Xopenex should start to work within minutes and you should start to see an improvement in your symptoms."
Answered by AI