Your session is about to expire
← Back to Search
High Sodium Diet and External Abdominal Compression in POTS
Phase 1
Waitlist Available
Led By Italo Biaggioni, MD
Research Sponsored by Vanderbilt University
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial Must have
Be between 18 and 65 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up 2 hours post baseline
Awards & highlights
No Placebo-Only Group
Summary
The investigators will test to determine if an external Automated Abdominal Binder (non-commercial product) during high sodium diet improves orthostatic tolerance, compared to wearing the binder during a low sodium diet session.
Eligible Conditions
- Postural Tachycardia Syndrome
- Postural Orthostatic Tachycardia Syndrome
Timeline
Screening ~ 3 weeks3 visits
Treatment ~ Varies
Follow Up ~ 2 hours post baseline
Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~2 hours post baseline
Treatment Details
Study Objectives
Study objectives can provide a clearer picture of what you can expect from a treatment.Primary study objectives
Change from baseline in orthostatic tachycardia
Secondary study objectives
Change from baseline in orthostatic symptoms
Awards & Highlights
No Placebo-Only Group
All patients enrolled in this study will receive some form of active treatment.
Trial Design
2Treatment groups
Experimental Treatment
Group I: Low Sodium DietExperimental Treatment1 Intervention
participants will consume a diet (10 milliequivalent Na+/day)for 4-5 days prior to study day.
Group II: High sodium dietExperimental Treatment1 Intervention
Participants will consume a diet high in sodium (300 milliequivalent Na+/day) for 4-5 days prior to study intervention.
Find a Location
Who is running the clinical trial?
Vanderbilt UniversityLead Sponsor
710 Previous Clinical Trials
6,143,367 Total Patients Enrolled
Italo Biaggioni, MDPrincipal InvestigatorVanderbilt University
28 Previous Clinical Trials
1,441 Total Patients Enrolled