← Back to Search

Tyrosine Kinase Inhibitor

TPX-0131 for Non-Small Cell Lung Cancer

Phase 1
Waitlist Available
Research Sponsored by Turning Point Therapeutics, Inc.
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up approximately 34 months
Awards & highlights
No Placebo-Only Group

Summary

This trial is testing a new drug to treat patients with lung cancer that has progressed or spread, and who have a specific genetic change (ALK+). The trial will assess the safety and effectiveness of the drug.

Eligible Conditions
  • Non-Small Cell Lung Cancer
  • Solid Tumors
  • Metastatic Tumor
  • Gene Mutation

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~approximately 34 months
This trial's timeline: 3 weeks for screening, Varies for treatment, and approximately 34 months for reporting.

Treatment Details

Study Objectives

Study objectives can provide a clearer picture of what you can expect from a treatment.
Primary study objectives
Define the Recommended Phase 2 Dose
Incidence of first cycle dose-limiting toxicities (DLTs) of TPX-0131
Secondary study objectives
Adverse events (AEs)

Awards & Highlights

No Placebo-Only Group
All patients enrolled in this study will receive some form of active treatment.

Trial Design

1Treatment groups
Experimental Treatment
Group I: TPX-0131Experimental Treatment1 Intervention
The Phase 1 part of the study will determine the safety, tolerability, PK, MTD, and RP2D of TPX-0131.

Find a Location

Who is running the clinical trial?

Turning Point Therapeutics, Inc.Lead Sponsor
9 Previous Clinical Trials
866 Total Patients Enrolled
Bristol-Myers SquibbStudy DirectorBristol-Myers Squibb
1,568 Previous Clinical Trials
3,384,353 Total Patients Enrolled
Eric Park, M.D.Study DirectorTurning Point Therapeutics
1 Previous Clinical Trials
155 Total Patients Enrolled
~3 spots leftby Nov 2025
Unbiased ResultsWe believe in providing patients with all the options.
Your Data Stays Your DataWe only share your information with the clinical trials you're trying to access.
Verified Trials OnlyAll of our trials are run by licensed doctors, researchers, and healthcare companies.
Back to top